NCT04414540 2025-12-19Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer PatientsUniversity of CincinnatiPhase 2 Active not recruiting20 enrolled
NCT03618654 2025-05-15Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell CarcinomaThomas Jefferson UniversityPhase EARLY_PHASE1 Completed38 enrolled