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Thrombocythemia, Essential × imetelstat × Clear all

Phase

Status

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Conditions

Recurrence 5 Myelodysplastic Syndromes 3 Primary Myelofibrosis 2 Oligodendroglioma 2 Neuroblastoma 2 Neoplasms, Plasma Cell 2 Myeloproliferative Disorders 2 Multiple Myeloma 2 Lymphoma 2 Leukemia, Myeloid, Acute 2 Glioblastoma 2 Astrocytoma 2 Thrombocytosis 1 Thrombocythemia, Essential 1 Sezary Syndrome 1 Rhabdomyosarcoma 1 Polycythemia Vera 1 Polycythemia 1 Osteosarcoma 1 Optic Nerve Glioma 1 Neuroectodermal Tumors, Primitive, Peripheral 1 Neoplasms, Neuroepithelial 1 Mycosis Fungoides 1 Lymphoproliferative Disorders 1 Lymphoma, T-Cell, Peripheral 1 Lymphoma, T-Cell, Cutaneous 1 Lymphoma, Large-Cell, Anaplastic 1 Lymphoma, Large B-Cell, Diffuse 1 Lymphoma, Extranodal NK-T-Cell 1 Lung Neoplasms 1

Interventions

fludarabine phosphate 23 Cyclophosphamide 21 Peripheral Blood Stem Cell Transplantation 19 Busulfan 14 ruxolitinib 12 Cyclosporine 12 Whole-Body Irradiation 11 Tacrolimus 11 Mycophenolic Acid 11 Methotrexate 10 Antilymphocyte Serum 10 Filgrastim 7 Decitabine 7 fludarabine 6 Etoposide 6 11-(2-pyrrolidin-1-ylethoxy)-14,19-dioxa-5,7,26-triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene 6 Radiotherapy 5 Methylprednisolone 5 Cytarabine 5 peginterferon alfa-2a 4 Prednisone 4 Melphalan 4 Biopsy 4 givinostat hydrochloride 3 givinostat 3 bomedemstat 3 anagrelide 3 Watchful Waiting 3 Thiotepa 3 Stem Cell Transplantation 3

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT01243073 2016-01-26

ET/PV

Geron Corporation

Phase 2 Completed

Polycythemia Vera, Thrombocythemia, Essential

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