Clinical Trials

50 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Laryngeal Diseases, Mouth Neoplasms, Neoplasms, Tongue Neoplasms

NCT07203911 2025-10-02

SURGIO

200 enrolled

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms, Tongue Neoplasms

NCT00765440 2025-09-30

Study of Nutrition Regimens in Treating Patients With Cancer of the Upper Aerodigestive Tract

Phase 3 Completed

311 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Infections, Tongue Neoplasms, Malnutrition

NCT00875849 2025-09-30

AACER

53 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT07124520 2025-08-15

A Study of Tongue Strength and Endurance Using the Iowa Oral Performance Instrument (IOPI) Tongue Strength Trainer in People With Oral Tongue Cance

60 enrolled

Tongue Neoplasms

NCT00665392 2025-08-01

ECHO-07

42 enrolled 24 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT04738786 2025-05-18

Clinical Study Evaluating the Proper Surgical Safety Margin for Early Stage Oral Tongue Cancers

Phase NA Terminated

125 enrolled

Margins of Excision, Carcinoma, Squamous Cell, Tongue Neoplasms

NCT02584270 2025-05-16

PGSRT

40 enrolled

Mouth Neoplasms, Tongue Neoplasms

NCT03181035 2024-08-12

FAITH

Phase 1/2 Suspended

10 enrolled

Tongue Neoplasms

NCT01847326 2024-07-31

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer

48 enrolled

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT06169605 2024-05-29

Assessment of the Effect of Tumor Thickness and Site on Level IV Cervical Lymph Nodes in Squamous Cell Carcinoma of the Tongue and Floor of the Mouth: A Case Series Study

20 enrolled

Tongue Neoplasms

NCT04337853 2023-11-03

Radiotherapy of Tongue Cancer Using an Intraoral Stent

13 enrolled

Head and Neck Neoplasms, Tongue Neoplasms

NCT01332279 2023-04-04

Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy

Phase 1 Withdrawn

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT05740774 2023-02-23

Surgical Margin Assessment by 3D Ultrasound

Phase NA Unknown

7 enrolled

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Tongue Neoplasms

NCT02295540 2022-09-28

Hypofractionated Radiation Therapy Followed by Surgery in Treating Patients With Advanced Squamous Cell Carcinoma of the Oral Cavity

Phase NA Withdrawn

Tongue Neoplasms

NCT04059861 2021-12-27

Ultrasound in Tongue Cancer- a Help to Decide Depth of Invasion and to Improve the Surgical Margin

42 enrolled

Margins of Excision, Tongue Neoplasms

NCT00293462 2021-07-30

GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Phase 3 Completed

91 enrolled 16 charts

CNSHead & Neck

Head and Neck Neoplasms, Radiation Injuries, Stomatitis, Tongue Neoplasms, Esthesioneuroblastoma, Olfactory

NCT02177838 2021-04-21

Cetuximab and Radiation Therapy in Treating Patients With Stage III-IV Head and Neck Cancer

Phase NA Terminated

8 enrolled 9 charts

Squamous Cell Carcinoma of Head and Neck, Tongue Neoplasms

NCT00833261 2020-08-21

Nab-Paclitaxel, Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer

37 enrolled 6 charts

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Tongue Neoplasms, Carcinoma, Verrucous

NCT00851877 2020-08-21

Nab-Paclitaxel, Cisplatin, and Cetuximab With Concurrent Radiation Therapy for Locally Advanced Head and Neck Cancer

37 enrolled 9 charts

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT01469429 2020-02-20

Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer.

70 enrolled

Squamous Cell Carcinoma of Head and Neck, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Paranasal Sinus Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms

NCT01504932 2020-02-20

Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors

42 enrolled

Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms, Tongue Neoplasms

NCT01816841 2020-01-30

Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care

68 enrolled

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Mouth Neoplasms, Tongue Neoplasms

NCT04126226 2019-10-15

Quality of Life in Patients Treated for Tongue and/or Jaw Neoplasia Before and After Speech Therapy

30 enrolled

Communication Disorders, Deglutition Disorders, Jaw Neoplasms, Mouth Neoplasms, Speech Intelligibility, Tongue Neoplasms

NCT01806675 2019-10-03

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

BreastCNSGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

25 enrolled 14 charts

Brain Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Colonic Neoplasms, Glioblastoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Salivary Gland Neoplasms, Tongue Neoplasms, Esthesioneuroblastoma, Olfactory, Gliosarcoma, Breast Neoplasms, Male

NCT02849379 2019-09-12

Combination of Cryosurgey and NK Immunotherapy for Recurrent Tongue Cancer

30 enrolled

Tongue Neoplasms

NCT02123511 2019-04-30

Acetylcysteine Rinse in Reducing Saliva Thickness and Mucositis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

Phase EARLY_PHASE1 Terminated

34 enrolled 16 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms, Mucositis

NCT00499733 2019-01-18

Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer

19 enrolled

BreastCNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Chondrosarcoma, Colonic Neoplasms, Carcinoma, Hepatocellular, Melanoma, Neoplasms, Neoplasms, Unknown Primary, Pancreatic Neoplasms, Prostatic Neoplasms, Salivary Gland Neoplasms, Sarcoma, Osteosarcoma, Tongue Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Breast Neoplasms, Male, Small Cell Lung Carcinoma, Intraocular Lymphoma

NCT02035527 2018-05-24

Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

3 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell, Salivary Gland Neoplasms, Tongue Neoplasms

NCT01316757 2018-02-26

Carboplatin, Paclitaxel, Cetuximab, and Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Head and Neck Squamous Cell Cancer

24 enrolled

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT02068157 2017-10-11

Interstitial Photodynamic Therapy in Treating Patients With Recurrent Head and Neck Cancer

Phase 2 Terminated

3 enrolled 8 charts

Lymphoid Interstitial Pneumonia, Squamous Cell Carcinoma of Head and Neck, Tongue Neoplasms

NCT00423930 2017-08-18

Cisplatin, Bevacizumab, and Intensity-Modulated Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer

44 enrolled 9 charts

GastrointestinalGenitourinaryGynecologicHead & NeckOther hematologic neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT00365508 2016-03-29

Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking

Phase 4 Completed

642 enrolled 8 charts

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Hypopharyngeal Neoplasms, Kidney Neoplasms, Laryngeal Neoplasms, Leukemia, Liver Neoplasms, Lung Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Tobacco Use Disorder, Tongue Neoplasms, Leukemia, Myeloid, Acute, Small Cell Lung Carcinoma

NCT01333085 2016-02-10

CAPRA

49 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT01334177 2015-03-05

TLR8 Agonist VTX-2337 and Cetuximab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Squamous Cell Cancer of Head and Neck

13 enrolled

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT01718223 2014-09-03

Photodynamic Therapy Using Temoporfin Before Surgery in Treating Patients With Recurrent Oral Cavity or Oropharyngeal Cancer

Phase NA Withdrawn

Squamous Cell Carcinoma of Head and Neck, Tongue Neoplasms

NCT00594724 2014-06-12

Improving Therapeutic Outcomes in the Tongue Carcinoma Patient: Assessment of Adaptation Using Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging

99 enrolled

Carcinoma, Neoplasms, Tongue Neoplasms

NCT01728480 2013-12-11

Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy

Phase 1 Withdrawn

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Tongue Neoplasms, Mucositis

NCT00101335 2013-07-11

Celecoxib in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

Head & NeckOther neoplasm

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Leukoplakia, Oral, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions, Tongue Neoplasms

NCT01854021 2013-05-17

Effects of Different General Anesthesia Methods on Immune Responses in Patients Undergoing Surgery for Tongue Cancer

Phase NA Unknown

60 enrolled

Tongue Neoplasms

NCT01674374 2013-05-15

Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have Undergone Chemoradiation Therapy

Phase 2 Withdrawn

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Tongue Neoplasms, Mucositis

NCT01313390 2011-12-12

DORA

Phase 1/2 Terminated

4 enrolled