NCT05044819 2026-03-17
Assessment of Potential for Chronic Liver Injury in Participants Treated With Epidiolex (Cannabidiol) Oral Solution
Jazz Pharmaceuticals
Phase 4 Active not recruiting
Clinical Trials
16 trialsNCT05864846 2026-03-12
EpiCom
Jazz Pharmaceuticals
Phase 4 Active not recruiting
NCT05485831 2026-02-17
EpiTALY
Jazz Pharmaceuticals
Recruiting
NCT07403266 2026-02-11
Spectrum
Oils4Cure
Phase 3 Recruiting
NCT02962414 2026-02-03
Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Novartis
Phase 3 Active not recruiting
NCT05252585 2026-02-03
A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)
Novartis
Phase 4 Active not recruiting
NCT07369505 2026-01-27
Sapu003 in Advanced mTOR-sensitive Solid Tumors
SAPU NANO (US) LLC
Phase 1 Recruiting
NCT07287202 2025-12-23
Safety, Tolerability, and Pharmacokinetics of SVG103 (Paxalisib) in Focal Cortical Dysplasia Type II (FCD-II), Tuberous Sclerosis Complex (TSC) or Hemimegalencephaly (HME)
Sovargen
Phase 1/2 Not yet recruiting
NCT05626634 2025-12-03
Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy
Longboard Pharmaceuticals
Phase 2 Completed
NCT03363763 2025-12-01
Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex
Aucta Pharmaceuticals, Inc
Phase 2 Terminated
NCT06965881 2025-11-21
Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults
GRIN Therapeutics, Inc.
Phase 1 Terminated
NCT06975605 2025-11-18
Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.
GRIN Therapeutics, Inc.
Phase 1 Completed
NCT05604170 2025-10-01
Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related Epilepsy
Marinus Pharmaceuticals
Phase 3 Terminated
NCT05323734 2025-07-11
Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy
Marinus Pharmaceuticals
Phase 3 Completed
NCT06392009 2025-07-03
Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II
GRIN Therapeutics, Inc.
Phase 1/2 Recruiting
NCT05059327 2025-06-04
Basimglurant (NOE-101) in Children, Adolescents, and Young Adults With TSC
Noema Pharma AG
Phase 2 Completed