NCT02962414 2026-02-03Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued TreatmentNovartisPhase 3 Active not recruiting206 enrolled
NCT05604170 2025-10-01Open-label Study of Adjunctive GNX Treatment in Children and Adults With TSC-related EpilepsyMarinus PharmaceuticalsPhase 3 Terminated117 enrolled 11 charts
NCT05323734 2025-07-11Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related EpilepsyMarinus PharmaceuticalsPhase 3 Completed129 enrolled 13 charts
NCT05495425 2024-11-22Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSCNobelpharmaPhase 3 Completed43 enrolled
NCT01906866 2024-04-23Efficacy and Safety of CircadinĀ® in the Treatment of Sleep Disturbances in Children With Neurodevelopment DisabilitiesNeurim Pharmaceuticals Ltd.Phase 3 Completed125 enrolled 22 charts
NCT02544750 2022-07-14An Open-label Extension Trial of Cannabidiol (GWP42003-P, CBD) for Seizures in Tuberous Sclerosis Complex (GWPCARE6)Jazz PharmaceuticalsPhase 3 Completed199 enrolled 14 charts
NCT02634931 2019-02-20Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis ComplexNobelpharmaPhase 3 Completed94 enrolled
NCT02635789 2017-02-02Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)NobelpharmaPhase 3 Completed62 enrolled