Clinical Trials Browser

Phase 2 × Interventional × Turcot syndrome × Clear all

NCT03607890 2026-03-16

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

Phase 2 Active not recruiting

Turcot syndrome, Microsatellite Instability

NCT04104893 2026-02-27

CHOMP

Phase 2 Active not recruiting

Turcot syndrome, Prostatic Neoplasms

NCT03767348 2026-02-13

IGNYTE

Phase 2 Active not recruiting

DermatologicThoracic

Turcot syndrome, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT07403877 2026-02-11

TORCH-OPTIMA

Phase 2 Not yet recruiting

Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT07369986 2026-01-27

IMMUNE-SAVE

Phase 2 Not yet recruiting

Turcot syndrome, Endometrial Neoplasms

NCT03228667 2026-01-14

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors

Phase 2 Active not recruiting

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Turcot syndrome, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Microsatellite Instability, Small Cell Lung Carcinoma

NCT07259473 2026-01-07

Pre-CATALIS

Phase 2 Not yet recruiting

Turcot syndrome

NCT03926338 2025-11-20

PICC

Phase 2 Recruiting

Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT03935893 2025-07-10

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Phase 2 Recruiting

DermatologicEndocrineGastrointestinalNETOther solid neoplasmSarcomaThoracic

Turcot syndrome, Mesothelioma, Pancreatic Neoplasms, Sarcoma, Stomach Neoplasms, Colorectal Neoplasms, Carcinoma, Merkel Cell, Neoplasms, Squamous Cell, Neuroendocrine Tumors, Microsatellite Instability

NCT05118724 2025-06-15

ANTONIO

Phase 2 Active not recruiting

Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT06646445 2025-06-13

PREMICES

Phase 2 Not yet recruiting

Gastrointestinal

Turcot syndrome, Colonic Neoplasms, Microsatellite Instability

NCT02983578 2025-05-06

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Phase 2 Active not recruiting

GastrointestinalThoracic

Turcot syndrome, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06278857 2024-12-03

SATELLITE

Phase 2 Recruiting

Turcot syndrome, Endometrial Neoplasms

NCT05913570 2023-06-22

MSI-H/dMMR

Phase 2 Unknown

Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT05371197 2022-05-12

Envafolimab as Neoadjuvant Immuntherapy in Resectable Local Advanced dMMR/MSI-H Colorectal Cancer

Phase 2 Unknown

Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT03050814 2021-12-20

Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004

Phase 2 Terminated

30 enrolled 15 charts

Gastrointestinal

Turcot syndrome, Colorectal Neoplasms

NCT04001101 2021-11-30

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Phase 2 Withdrawn

Gastrointestinal

Turcot syndrome, Neoplasm Metastasis, Colorectal Neoplasms

NCT04439214 2021-04-06

Testing Nivolumab as a Potential Targeted Treatment in Cancers With Mismatch Repair Deficiency (MATCH-Subprotocol Z1D)

Phase 2 Completed

47 enrolled 10 charts

LymphoidOther hematologic neoplasmPlasma cell

Turcot syndrome, Lymphoma, Multiple Myeloma, Hematologic Neoplasms