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Turcot syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Endometrial Hyperplasia, Endometrial Neoplasms, Microsatellite Instability

NCT03053466 2022-05-09

APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors

Phase 1 Completed

30 enrolled

Turcot syndrome, Neoplasms, Unknown Primary, Microsatellite Instability

NCT03652077 2021-11-15

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Phase 1 Completed

40 enrolled

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Turcot syndrome, Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Uterine Cervical Neoplasms, Esophageal Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04439214 2021-04-06

Testing Nivolumab as a Potential Targeted Treatment in Cancers With Mismatch Repair Deficiency (MATCH-Subprotocol Z1D)

Phase 2 Completed

47 enrolled 10 charts

LymphoidOther hematologic neoplasmPlasma cell

Turcot syndrome, Lymphoma, Multiple Myeloma, Hematologic Neoplasms

NCT04482608 2020-07-27

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival

Completed

671 enrolled

Turcot syndrome

Clinical Trials

Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome

APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Testing Nivolumab as a Potential Targeted Treatment in Cancers With Mismatch Repair Deficiency (MATCH-Subprotocol Z1D)

The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival