Clinical Trials Browser

Interventional × Has results × Uveal Melanoma × Clear all

NCT01979523 2026-03-19

Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma

Phase 2 Active not recruiting

42 enrolled 13 charts

Uveal Melanoma

NCT03070392 2026-03-17

Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal Melanoma

Phase 2 Completed

378 enrolled 15 charts 1 FDA

Uveal Melanoma, Melanoma

NCT02858869 2026-03-09

Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases

Phase 1 Completed

25 enrolled 14 charts

CNSDermatologicThoracic

Uveal Melanoma, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma

NCT03417739 2026-02-25

A Phase II Study of BVD-523 in Metastatic Uveal Melanoma

Phase 2 Terminated

13 enrolled 9 charts

Uveal Melanoma

NCT04552223 2026-02-11

Nivolumab Plus Relatlimab in Patients With Metastatic Uveal Melanoma

Phase 2 Completed

27 enrolled 9 charts

Uveal Melanoma

NCT01473004 2025-11-14

SIR-Spheres® 90Y Microspheres Treatment of Uveal Melanoma Metastasized to Liver

Phase 2 Completed

48 enrolled 10 charts

Uveal Melanoma, Melanoma

NCT03712904 2025-09-24

Stereotactic Body Radiation Therapy and Aflibercept in Treating Patients With Uveal Melanoma

Phase 2 Terminated

3 enrolled 9 charts

Uveal Melanoma

NCT05308901 2025-07-25

Lenvatinib Plus Pembrolizumab In Patients With Immune Checkpoint Inhibitor Naïve Metastatic Uveal Melanoma

Phase 2 Active not recruiting

6 enrolled 11 charts

Uveal Melanoma, Melanoma

NCT04720417 2025-07-15

Defactinib and VS-6766 for the Treatment of Patients With Metastatic Uveal Melanoma

Phase 2 Terminated

13 enrolled 13 charts

Uveal Melanoma

NCT03472586 2025-04-24

Ipilimumab and Nivolumab With Immunoembolization in Treating Participants With Metastatic Uveal Melanoma in the Liver

Phase 2 Completed

14 enrolled 8 charts

Uveal Melanoma

NCT01585194 2024-07-09

Nivolumab and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma

Phase 2 Completed

67 enrolled 12 charts

Uveal Melanoma

NCT00445965 2024-04-04

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Phase 2 Completed

78 enrolled 11 charts

CNSDermatologicGynecologicOther solid neoplasmSarcomaThoracic

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Chondrosarcoma, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neoplasm Metastasis, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Rhabdoid Tumor, Optic Nerve Glioma, Small Cell Lung Carcinoma, Desmoplastic Small Round Cell Tumor

NCT03052127 2024-02-01

Study in Subjects With Small Primary Choroidal Melanoma

Phase 1/2 Completed

57 enrolled 26 charts

Uveal Melanoma, Eye Neoplasms

NCT02223819 2023-12-06

Crizotinib in High-Risk Uveal Melanoma Following Definitive Therapy

Phase 2 Completed

34 enrolled 9 charts

Uveal Melanoma

NCT04589832 2023-11-22

Study of PAC-1 and Entrectinib for Patients With Metastatic Uveal Melanoma

Phase 1/2 Terminated

6 enrolled 9 charts

Uveal Melanoma

NCT02743611 2023-10-05

Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanoma

Phase 1/2 Terminated

4 enrolled 9 charts

DermatologicMyeloidOther hematologic neoplasm

Uveal Melanoma, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT02831933 2023-09-21

ENSIGN

Phase 2 Terminated

11 enrolled 9 charts

DermatologicThoracic

Uveal Melanoma, Lung Neoplasms, Melanoma, Neoplasm Metastasis

NCT03207347 2023-09-15

A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)

Phase 2 Completed

37 enrolled 15 charts

DermatologicGastrointestinalGenitourinaryOther solid neoplasmThoracic

Uveal Melanoma, Carcinoma, Renal Cell, Mesothelioma, Cholangiocarcinoma

NCT02570308 2023-03-21

A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma

Phase 1/2 Completed

146 enrolled 26 charts

Uveal Melanoma, Melanoma

NCT01835145 2022-08-04

Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed by Surgery

Phase 2 Completed

47 enrolled 12 charts

Uveal Melanoma

NCT02315066 2022-04-21

Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566

Phase 1 Completed

174 enrolled 68 charts

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Uveal Melanoma, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Head and Neck Neoplasms, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Lung Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT00084656 2022-04-14

Monoclonal Antibody Therapy and Vaccine Therapy in Treating Patients With Resected Stage III or Stage IV Melanoma

Phase 2 Completed

77 enrolled 13 charts

Uveal Melanoma, Melanoma

NCT02129075 2021-11-16

A Vaccine (CDX-1401) With or Without a Biologic Drug (CDX-301) for the Treatment of Patients With Stage IIB-IV Melanoma

Phase 2 Completed

60 enrolled 13 charts

Uveal Melanoma, Melanoma

NCT02771340 2020-10-01

Study Evaluating Single and Repeated Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma

Phase 1 Completed

10 enrolled 10 charts

Uveal Melanoma, Choroid Neoplasms

NCT01801358 2020-09-16

A Phase Ib/II Study of AEB071 and MEK162 in Adult Patients With Metastatic Uveal Melanoma

Phase 1/2 Terminated

38 enrolled 31 charts

Uveal Melanoma, Melanoma

NCT02363283 2020-08-21

Glembatumumab Vedotin in Treating Patients With Metastatic or Locally Recurrent Uveal Melanoma

Phase 2 Completed

37 enrolled 12 charts

Uveal Melanoma

NCT02336763 2020-07-24

Radiation Therapy in Preventing Liver Metastases in Patients With Uveal Melanoma Who HaveMonosomy 3 or DecisionDx Class 2 Disease and Are More Likely to Develop Liver Metastases

Phase NA Terminated

2 enrolled 3 charts

Uveal Melanoma

NCT01989572 2020-07-07

Sargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By Surgery

Phase 3 Completed

815 enrolled 10 charts

Uveal Melanoma, Melanoma

NCT01413191 2020-02-19

Cixutumumab in Treating Patients With Metastatic Melanoma of the Eye

Phase 2 Completed

18 enrolled 9 charts

Uveal Melanoma

NCT02158520 2020-01-21

Nab-Paclitaxel and Bevacizumab or Ipilimumab as First-Line Therapy in Treating Patients With Stage IV Melanoma That Cannot Be Removed by Surgery

Phase 2 Completed

24 enrolled 10 charts

Uveal Melanoma, Melanoma

NCT00254397 2019-10-16

Melanoma Vaccine With Peptides and Leuprolide

Phase 2 Completed

98 enrolled 11 charts

Uveal Melanoma, Eye Neoplasms, Melanoma, Skin Neoplasms

NCT02359851 2019-09-18

Pembrolizumab in Treating Patients With Advanced Uveal Melanoma

Phase 2 Terminated

5 enrolled 13 charts

Uveal Melanoma

NCT01471054 2019-09-03

Dexamethasone Intravitreal Implant for Treatment of Macular Edema After Plaque Radiotherapy of Uveal Melanoma

Phase 2 Terminated

6 enrolled 10 charts

Uveal Melanoma, Macular Edema

NCT01100528 2019-02-26

Dacarbazine and Recombinant Interferon Alfa-2b in Treating Patients With Primary Uveal Melanoma With Genetic Imbalance

Phase 2 Completed

38 enrolled 10 charts

Uveal Melanoma

NCT00121225 2019-01-29

Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma

Phase 2 Completed

32 enrolled 11 charts

Uveal Melanoma, Melanoma

NCT01200238 2018-10-18

STA-9090(Ganetespib) in Metastatic Ocular Melanoma

Phase 2 Completed

17 enrolled 12 charts

Uveal Melanoma

NCT01814046 2018-10-11

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma

Phase 2 Terminated

24 enrolled 13 charts

Uveal Melanoma, Neoplasm Metastasis

NCT00243061 2018-08-27

AZD2171 in Treating Patients With Recurrent or Stage IV Melanoma

Phase 2 Completed

24 enrolled 12 charts

Uveal Melanoma, Melanoma

NCT01961115 2018-06-08

Epacadostat and Vaccine Therapy in Treating Patients With Stage III-IV Melanoma

Phase 2 Completed

11 enrolled 12 charts

Uveal Melanoma, Melanoma

NCT00450255 2018-05-24

VEGF Trap in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

Phase 2 Completed

41 enrolled 7 charts

Uveal Melanoma, Melanoma

NCT01533948 2018-05-09

Axitinib in Treating Patients With Melanoma That is Metastatic or Cannot Be Removed by Surgery

Phase 2 Terminated

25 enrolled 11 charts

Uveal Melanoma, Melanoma

NCT01252251 2017-08-01

RAD001 (Everolimus) and Pasireotide (SOM230) LAR in Patients With Advanced Uveal Melanoma

Phase 2 Completed

14 enrolled 12 charts

Uveal Melanoma

NCT01143402 2017-07-26

Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye

Phase 2 Completed

120 enrolled 8 charts

Uveal Melanoma

NCT00680225 2017-04-12

Lucentis as an Adjuvant Therapy With TTT-ICG Based in Choroidal Melanoma

Phase 3 Completed

10 enrolled 4 charts

Uveal Melanoma

NCT00482911 2017-03-27

Lenalidomide, Sunitinib, and Cyclophosphamide in Treating Patients With Stage IV Eye Melanoma

Phase 2 Terminated

12 enrolled 10 charts

Uveal Melanoma

NCT00398073 2017-03-16

Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma

Phase 1 Completed

35 enrolled 9 charts

Uveal Melanoma, Melanoma

NCT00109005 2017-01-02

Lenalidomide (Revlimid) to Treat Advanced Ocular Melanoma

Phase 2 Completed

17 enrolled 11 charts

Uveal Melanoma, Melanoma

NCT01251978 2016-10-19

Ranibizumab as Adjuvant Therapy for the Treatment of Choroidal Melanoma (Cohort 2)

Phase 2 Completed

10 enrolled 7 charts

Uveal Melanoma

NCT00738361 2016-02-12

Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed By Surgery

Phase 2 Completed

4 enrolled 7 charts

Uveal Melanoma

NCT01200342 2016-02-11

Genasense, Carboplatin, Paclitaxel (GCP) Combination in Uveal Melanoma

Phase 2 Terminated

7 enrolled 3 charts

Uveal Melanoma, Melanoma