Clinical Trials Browser

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT05806385 2025-09-09

LOGIC

Phase 1/2 Not yet recruiting

36 enrolled

Breast

Triple Negative Breast Neoplasms

NCT05949099 2025-09-08

Study of Cryoablation and Nirogacestat for Desmoid Tumor

Phase 2 Recruiting

28 enrolled

Sarcoma

Desmoid Tumors

NCT06127303 2025-09-05

Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC

Phase 2 Recruiting

54 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT07070700 2025-08-12

CASTLE-ZS-02

Phase 2 Recruiting

56 enrolled

Gastrointestinal

Cirrhosis, Familial, with Pulmonary Hypertension, Cholangiocarcinoma

NCT06839001 2025-06-26

CRYSTAL - SIX

Phase 3 Recruiting

750 enrolled

Breast

Breast Neoplasms

NCT03325101 2025-06-12

Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma

Phase 1/2 Terminated

7 enrolled 11 charts

Dermatologic

Melanoma

NCT06246968 2025-05-21

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

Phase 1 Recruiting

30 enrolled

Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03035331 2025-05-16

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

Phase 1/2 Completed

11 enrolled 12 charts

LymphoidOther hematologic neoplasm

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, T-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT05972343 2025-05-06

COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients

Recruiting

100 enrolled

Breast

Breast Neoplasms

NCT04522570 2025-04-30

Thermal Ablation of Cervical Metastases From Thyroid Carcinoma

Phase NA Active not recruiting

84 enrolled

Head & Neck

Lymphatic Metastasis, Thyroid Neoplasms, Carcinoma, Medullary

NCT04797039 2025-04-23

MRI-Guided Cryoablation for Focal Native Prostate Cancer

Recruiting

100 enrolled

Disease

Clinical Trials

LUBRECA

SEED-CRYO: Sequential 125I Seed Implantation Followed by Cryoablation vs Single-Modality Local Therapy in Unresectable Solid Tumors

Lesion-Allocated Therapy for Multiple Metastases and Tumor-Zoned Treatment for Bulky Tumors: A Phase II Study of Iodine-125 Seed Implantation Combined With Cryoablation in High-Burden Metastatic Disease

Stereotactic Guided Biopsy and Cryoablation

NAP-C/R

Cryoablation for the Treatment of Metastatic Cancer

CRYO-1

Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

CRYOMUNE

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

Safety and Efficacy Evaluation of Cryoablation in the Treatment of Ground-Glass Nodules

Cryoablation+Ipilimumab+Nivolumab in Melanoma

PRECICE

Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

TA-P-OLIM

Evaluation of Efficacy of Minimally Invasive Local Therapy for Lung Tumors and Its Impact on Breathing Function

CRYODESMO-02

Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

LOGIC

Study of Cryoablation and Nirogacestat for Desmoid Tumor

Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC

CASTLE-ZS-02

CRYSTAL - SIX

Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients

Thermal Ablation of Cervical Metastases From Thyroid Carcinoma

MRI-Guided Cryoablation for Focal Native Prostate Cancer