Clinical Trials

Colorectal Neoplasms

NCT07152821 2026-03-10

BATTMAN

Phase 3 Recruiting

834 enrolled

Colorectal Neoplasms

NCT06279130 2026-03-05

NEOASIS

Phase 2/3 Recruiting

133 enrolled

Other solid neoplasm

Resectable MMR-deficient Solid Tumors

NCT06346197 2026-03-02

CIME

Phase 3 Recruiting

132 enrolled

Phase EARLY_PHASE1 Recruiting

Neoplasm Metastasis, Stomach Neoplasms

NCT07193862 2026-02-27

Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis

10 enrolled

Phase 1/2 Active not recruiting

Colorectal Cancer Metastatic

NCT05928806 2026-02-11

ARCITECT

Phase 2 Suspended

120 enrolled

Genitourinary

Advanced Renal Cell Carcinoma

NCT05672316 2026-01-28

Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy

28 enrolled

Colorectal Neoplasms

NCT04028063 2026-01-27

Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas

65 enrolled

Sarcoma

NCT06589440 2026-01-15

Phase 2 Study of SR-8541A in Combination With Botensilimab and Balstilimab in Subjects With Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)

70 enrolled

Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)

NCT05363709 2026-01-14

BALSTILIMAB on Viral Clearance in HPV+ Oropharyngeal Cancer Patients

Phase 1 Active not recruiting

Head & Neck

Oropharyngeal Neoplasms

NCT06076837 2026-01-12

The Seven Trial: Exploiting the Unfolded Protein Response

6 enrolled

Pancreatic Cancer Metastatic

NCT06411691 2025-12-18

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Phase 1 Recruiting

54 enrolled

Colonic Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT06782932 2025-12-03

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

Phase 1/2 Recruiting

38 enrolled

Adenocarcinoma, Carcinoma, Pancreatic Neoplasms

NCT06251973 2025-12-02

A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancer

37 enrolled

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Stomach Neoplasms

NCT06843434 2025-12-02

A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma

40 enrolled

Phase 1/2 Active not recruiting

Microsatellite Stable Rectal Carcinoma

NCT05627635 2025-11-10

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Phase 1/2 Active not recruiting

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT05205330 2025-10-29

Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers

107 enrolled

Stomach Neoplasms, Colorectal Neoplasms

NCT06843551 2025-08-14

EMPIRE

Pancreatic Neoplasms

NCT03104699 2025-07-30

A Study of AGEN2034 in Advanced Tumors and Cervical Cancer

Phase 1/2 Completed

211 enrolled 29 charts

Gynecologic

Uterine Cervical Neoplasms

NCT05571293 2025-07-30

NEST-1

Phase 2 Suspended

36 enrolled

Diabetes Mellitus, Insulin-Dependent, 12, Colorectal Neoplasms

NCT06780787 2025-06-26

FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

26 enrolled

Rectal Neoplasms

NCT05891821 2025-05-08

Assessment of the Safety and Efficacy of Balstilimab for the Treatment of Relapsed/Refractory Lymphomas (IMMONC0001)

Lymphoid

Lymphoma

NCT06322108 2025-05-08

Assessment of the Safety and Efficacy of Balstilimab in Combination With Botensilimab for the Treatment of Non-Small Cell Lung Cancer (IMMONC0008)

45 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT05377528 2025-04-30

Study of AGEN1571 in Participants With Advanced Solid Tumors

Phase 1 Completed

22 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT06300463 2025-04-06

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

24 enrolled