Clinical Trials Browser

Bronchial Neoplasms, Carcinoma, Carcinoma, Non-Small-Cell Lung, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Site, Hereditary Sensory and Autonomic Neuropathies, Respiratory Tract Diseases, Respiratory Tract Neoplasms

NCT04185883 2025-10-22

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

Phase 1 Active not recruiting

610 enrolled

Other solid neoplasmSarcoma

Advanced Solid Tumors

NCT04303780 2025-10-14

Study to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200).

Phase 3 Active not recruiting

345 enrolled 11 charts

Thoracic

KRAS p, G12c Mutated /Advanced Metastatic NSCLC

NCT04892017 2025-10-10

A Phase 1/2 Study of Inlexisertib (DCC-3116) in Patients With RAS/MAPK Pathway Mutant Solid Tumors

Phase 1/2 Active not recruiting

144 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT07143513 2025-09-12

Real World Evaluation of Sotorasib Among Chinese Non-Small Cell Lung Cancer Patients

Recruiting

115 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04380753 2025-07-23

AMG 510 Ethnic Sensitivity Study (CodeBreaK 105).

Phase 1 Active not recruiting

12 enrolled 12 charts

Other solid neoplasm

Advanced/Metastatic Solid Tumors With KRAS p.G12C Mutation

NCT05374538 2025-05-01

VIC-1911 Monotherapy in Combination With Sotorasib for the Treatment of KRAS G12C-Mutant Non-Small Cell Lung Cancer

Phase 1 Terminated

3 enrolled 13 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04720976 2025-04-11

JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors

Phase 1/2 Completed

58 enrolled

Other solid neoplasmThoracic

Solid Tumor