Clinical Trials Browser

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT05027386 2026-02-05

Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastoma: A Single-arm, Phase I/II，Multi-center, Clinical Study.

Phase 1/2 Recruiting

125 enrolled

CNS

Neuroblastoma

NCT07391215 2026-02-05

5G-PEARL

Phase 1/2 Recruiting

64 enrolled

CNS

Glioblastoma

NCT05331521 2026-02-03

ImproveCodel

Phase 3 Recruiting

406 enrolled

CNS

Oligodendroglioma

NCT06388733 2026-02-03

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Phase 3 Recruiting

450 enrolled

CNS

Brain Neoplasms, Glioblastoma

NCT05629702 2026-01-30

ARISTOCRAT

Phase 2 Recruiting

120 enrolled

CNS

Brain Neoplasms, Marijuana Abuse, Glioblastoma, Recurrence

NCT07375563 2026-01-29

NB-NK-2026

Phase 3 Recruiting

5 enrolled

CNS

Neuroblastoma, Ganglioneuroblastoma

NCT06208657 2026-01-28

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Phase 1/2 Recruiting

90 enrolled

CNSLymphoid

Lymphoma, Neoplasms, Recurrence, Central Nervous System Neoplasms

NCT07025226 2026-01-26

Senolytics

Phase EARLY_PHASE1 Recruiting

10 enrolled

CNS

Glioma

NCT06630260 2026-01-21

5G-RUBY

Phase 1/2 Recruiting

182 enrolled

CNS

Glioblastoma

NCT02813135 2026-01-16

ESMART

Phase 1/2 Recruiting

472 enrolled

Tumor-Agnostic

Neoplasms

NCT04623931 2026-01-14

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Phase 2 Recruiting

40 enrolled

CNS

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT05588453 2026-01-12

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

Phase 1/2 Recruiting

30 enrolled

CNSDermatologic

Brain Neoplasms, Melanoma

NCT05083754 2026-01-09

Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma

Phase 1 Recruiting

50 enrolled

CNS

Glioblastoma

NCT05106296 2026-01-09

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Phase 1 Recruiting

37 enrolled

CNS

Brain Neoplasms, Ependymoma, Glioblastoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT06861244 2026-01-07

PNOC031

Phase 2 Recruiting

70 enrolled

Neuroectodermal Tumors, Primitive, Pyloric Stenosis, Hypertrophic

NCT05400603 2025-12-26

Aflac-NBL-2002

Phase 1 Recruiting

24 enrolled

CNSSarcoma

Neuroblastoma, Osteosarcoma

Clinical Trials

MetroWilms

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

METTSEO

EF-41

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

CERTIS1

A Clinical Trial Testing the Safety of the Investigational Drug Pumitamig (BNT327) and How Well it Works in Patients With Recurrent Glioblastoma

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Relapsed SCLC

A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma

Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

A Study of Repotrectinib in Combination With Chemotherapy in Children and Young Adults With Solid Tumor Cancer

Surgical Pembro +/- Olaparib w TMZ for rGBM

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

BRIDGES

A Phase II Trial of LM103 in Advanced Melanoma

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

MEMMAT

DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM)

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

Phase 1/2 Trial to Evaluate the Safety and Efficacy of PEEL-224 in Combination With Vincristine and Temozolomide in Adolescents and Young Adults With Relapsed or Refractory Sarcomas

Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastoma: A Single-arm, Phase I/II，Multi-center, Clinical Study.

5G-PEARL

ImproveCodel

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

ARISTOCRAT

NB-NK-2026

Optimal Precision TherapIes to CustoMISE Care in Childhood and Adolescent Cancer

Senolytics

5G-RUBY

ESMART

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma

Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

PNOC031

Aflac-NBL-2002