Clinical Trials

31 enrolled

Advanced Malignancies

NCT03590574 2026-03-16

Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma

20 enrolled 34 charts

Lymphoid

Immunoblastic Lymphadenopathy, Lymphoma, T-Cell, Lymphoma, Large-Cell, Anaplastic

NCT06540066 2026-03-16

A Study of BGB-B3227 Alone and in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors

35 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT04729387 2026-03-13

Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected

358 enrolled

Gynecologic

Ovarian Neoplasms

NCT05935098 2026-03-13

BGB-A3055 Alone and in Combination With Tislelizumab in Participants With Solid Tumors

99 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT06038539 2026-03-13

Efficacy and Safety of the Proposed Biosimilar Pertuzumab (PERT-IJS) Versus EU-Perjeta® Along With Trastuzumab and Chemotherapy (Carboplatin and Docetaxel) as Neoadjuvant Treatment in Chemotherapy naïve Patients With Early Stage or Locally Advanced HR Negative and HER2 Positive Breast Cancer

55 enrolled

Breast

HR Negative HER2 Positive Early Breast Cancer or Locally Advanced Breast Cancer Patients

NCT06173505 2026-03-13

Study of Vudalimab or Pembrolizumab in Combination With Chemotherapy as First-line Treatment in Patients With Advanced NSCLC

28 enrolled

Carcinoma, Non-Small-Cell Lung

NCT06391918 2026-03-13

Phase 1 Study of GEN2 in Patients With Advanced Solid Tumors

37 enrolled

Solid Tumor, Adult

NCT04796324 2026-03-12

Anti-tumor Effect of Ixabepilone in Metastatic Breast Cancer (mBC) Selected by the Ixabepilone DRP.

13 enrolled 8 charts

Breast

Breast Neoplasms

NCT05994157 2026-03-12

Phase 1, Open-label, Dose-escalation Trial With CD38-SADA:177 Lu-DOTA Drug Complex in Subjects With Relapsed or Refractory Non-Hodgkin Lymphoma

1 enrolled

Lymphoid

Lymphoma, Non-Hodgkin

NCT04832854 2026-03-11

A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemotherapy, in Participants With Previously Untreated Locally Advanced Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer

50 enrolled 18 charts

Carcinoma, Non-Small-Cell Lung

NCT05537766 2026-03-10

ZUMA-25

19 enrolled 28 charts

Burkitt Lymphoma, Leukemia, Hairy Cell, Waldenstrom Macroglobulinemia, Recurrence

NCT05636267 2026-03-09

Study of AK119 and AK112 With or Without Chemotherapy for NSCLC Patients

59 enrolled

NSCLC

NCT05926960 2026-03-09

PORTSIDE

38 enrolled

Dermatologic

Melanoma, Skin Neoplasms

NCT05346484 2026-03-06

MAST

66 enrolled

Gastrointestinal

Bile Duct Neoplasms, Neoplasm Metastasis, Cholangiocarcinoma

NCT06063317 2026-03-06

OASIS

25 enrolled

Bites and Stings

NCT04222972 2026-03-05

AcceleRET-Lung

223 enrolled 18 charts

Head & NeckThoracic

Adenocarcinoma, Bronchial Diseases, Carcinoma, Carcinoma, Bronchogenic, Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Germ Cell and Embryonal, Neoplasms, Nerve Tissue, Respiratory Tract Diseases, Respiratory Tract Neoplasms, Thoracic Neoplasms

NCT06287463 2026-03-05

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

29 enrolled

DermatologicThoracic

Carcinoma, Non-Small-Cell Lung, Melanoma

NCT05721222 2026-03-04

Trial of PRO1160 (GEN1160) in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) (PRO1160-001)

GenitourinaryHead & NeckLymphoid

42 enrolled

Nasopharyngeal Carcinoma, Carcinoma, Renal Cell, Lymphoma, Non-Hodgkin

NCT04895748 2026-03-03

DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

CNSEndocrineGenitourinary

40 enrolled

Hereditary leiomyomatosis and renal cell cancer, Carcinoma, Renal Cell, von Hippel-Lindau Disease, Paraganglioma, Pheochromocytoma

NCT05714345 2026-03-02

EXPAND

2 enrolled 8 charts

Lymphoid

Lymphoma, Recurrence

NCT05522387 2026-02-27

An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease

11 enrolled

CNS

Alzheimer Disease, Mental Disorders, Brain Diseases, Central Nervous System Diseases, Dementia, Inflammation, Nervous System Diseases, Neurodegenerative Diseases, Neurocognitive Disorders, Tauopathies

NCT01068782 2026-02-25

Multiple Doses and Regimens of Cabozantinib in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

19 enrolled 10 charts

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma

NCT06171789 2026-02-25

PRO1107 in Patients With Advanced Solid Tumors

BreastGenitourinaryGynecologicThoracic

33 enrolled

Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell, Ovarian Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT04059484 2026-02-24

AMEERA-3

367 enrolled 30 charts

Breast

Breast Cancer Metastatic

NCT06587451 2026-02-24

Integrated Pharmacokinetics (PK)/Efficacy, Safety, and Immunogenicity Study to Demonstrate Similarity of JPB898, a Proposed Biosimilar to Nivolumab, to Opdivo® in Combination With Yervoy®

52 enrolled

Dermatologic

Melanoma

NCT06625515 2026-02-24

First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients With Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers

GastrointestinalGynecologic

17 enrolled

Colonic Neoplasms, Rectal Neoplasms, Endometrial Neoplasms, Microsatellite Instability

NCT05171049 2026-02-23

ASTER

1,150 enrolled

Classical hematology

Pulmonary Embolism, Venous Thrombosis, Venous Thromboembolism

NCT06005974 2026-02-23

A Study of REC-4881 in Participants With Cancers Which Have an AXIN1 or APC Mutation

18 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT06546553 2026-02-23

A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

DermatologicGastrointestinalGenitourinaryGynecologicHead & NeckThoracic

10 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Kidney Neoplasms, Melanoma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Rectal Diseases, Colorectal Neoplasms

NCT04876651 2026-02-20

The Present Study Aims to Compare Patients Who Receive the Investigational Product (177Lu-DOTA-rosopatamab) Plus Standard of Care, in Comparison to Standard of Care Only

16 enrolled

Genitourinary

Prostatic Neoplasms

NCT05381909 2026-02-20

A Study of BGB-24714 as Monotherapy and With Combination Therapies in Participants With Solid Tumors

157 enrolled

Solid Tumor, Adult

NCT05233436 2026-02-19

PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors

GastrointestinalHead & NeckThoracic

21 enrolled

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Stomach Neoplasms

NCT05386550 2026-02-19

Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION)

166 enrolled 15 charts

Head & Neck

Head and Neck Neoplasms, Laryngeal Diseases

NCT05578092 2026-02-19

A Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK Pathway

64 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Colorectal Neoplasms

NCT03779113 2026-02-18

An Open-label, Dose Escalation Trial to Evaluate the Safety and Pharmacokinetics of HMPL-523 in Patients With Lymphoma

69 enrolled 47 charts

Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell

NCT04817761 2026-02-18

SPARK-ALL: Calaspargase Pegol in Adults With ALL

Phase 2/3 Terminated

42 enrolled

Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT05462873 2026-02-17

A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors

GastrointestinalGenitourinaryHead & NeckThoracic

30 enrolled

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell

NCT05638334 2026-02-17

Immuno-positron Emission Tomography Study of 89Zr-S095012 in Patients With Advanced Solid Tumours

3 enrolled

Advanced Solid Tumor

NCT06026332 2026-02-17

ABLE-41

Terminated

202 enrolled

Genitourinary

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT06965309 2026-02-12

Efficacy and Safety of HN2301 in Refractory Myasthenia Gravis(MG)

Phase NA Terminated

9 enrolled

Myasthenia Gravis

NCT05551117 2026-02-09

Tamarack

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

192 enrolled 20 charts

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Carcinoma, Small Cell, Small Cell Lung Carcinoma, Prostatic Neoplasms, Castration-Resistant

NCT06331559 2026-02-09

Study of SIM0501 Alone and in Combination in Patients With Advanced Solid Tumors

13 enrolled

Advanced Solid Tumors

NCT06716853 2026-02-09

TEM-GU

10 enrolled

Genitourinary

Carcinoma, Renal Cell

NCT04809467 2026-02-04

topMIND

54 enrolled 23 charts

Leukemia, Lymphoma, Non-Hodgkin, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell

NCT04889989 2026-02-04

Microwave Ablation in Chinese Patients With Lung Tumors

Phase NA Terminated

13 enrolled 11 charts