NCT04551963 2024-10-26Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell MalignanciesBeiGenePhase 1 Completed26 enrolled 20 charts
NCT03028103 2023-06-26Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor PatientsIpsenPhase 1 Completed32 enrolled 30 charts
NCT02222922 2020-12-17A Study Of PF-06647020 For Adult Patients With Advanced Solid TumorsPfizerPhase 1 Completed138 enrolled 98 charts
NCT02122770 2019-01-07Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid TumorsTakedaPhase 1 Completed51 enrolled 30 charts
NCT02093390 2016-06-06A Phase 1 Study to Evaluate the Effects of Fluconazole and Atorvastatin on the Pharmacokinetics of TAK-385 in Healthy SubjectsMillennium Pharmaceuticals, Inc.Phase 1 Completed40 enrolled 23 charts