Clinical Trials Browser

Phase 3 × Has results × Lapatinib × Clear all

NCT03523585 2026-02-27

DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]

Phase 3 Completed

608 enrolled 17 charts

Breast

Breast Neoplasms

NCT00770809 2025-08-15

Paclitaxel and Trastuzumab With or Without Lapatinib in Treating Patients With Stage II or Stage III Breast Cancer That Can Be Removed by Surgery

Phase 3 Completed

305 enrolled 10 charts

Breast

Breast Neoplasms, Breast Neoplasms, Male

NCT00680901 2025-08-07

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

Phase 3 Completed

545 enrolled 24 charts

Gastrointestinal

Esophageal Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00490139 2025-03-21

ALTTO

Phase 3 Completed

8,381 enrolled 22 charts

Breast

Breast Neoplasms

NCT00667251 2025-03-21

Chemotherapy and Lapatinib or Trastuzumab in Treating Women With HER2/Neu-Positive Metastatic Breast Cancer

Phase 3 Completed

652 enrolled 50 charts

Breast

Breast Neoplasms

NCT01160211 2025-03-07

A Study to Compare the Safety and Efficacy of an Aromatase Inhibitor in Combination With Lapatinib, Trastuzumab or Both for the Treatment of Hormone Receptor Positive, HER2+ Metastatic Breast Cancer

Phase 3 Completed

369 enrolled 19 charts

Breast

Breast Neoplasms

NCT00272987 2023-04-28

ErbB2 Over-expressing Metastatic Breast Cancer Study Using Paclitaxel, Trastuzumab, and Lapatinib

Phase 3 Terminated

63 enrolled 22 charts

Breast

Breast Neoplasms

NCT00281658 2023-02-10

Study In Women And Men With Metastatic Breast Cancer That Have Overexpression Of ErbB2

Phase 3 Completed

444 enrolled 28 charts

Breast

Breast Neoplasms

NCT00508274 2021-09-21

Lapatinib +Capecitabine Treatment for Advanced Metastatic Breast Cancer in Women From China

Phase 3 Terminated

52 enrolled 12 charts

Breast

Breast Neoplasms

NCT00553358 2021-09-21

Neo ALTTO

Phase 3 Completed

455 enrolled 34 charts

Breast

Breast Neoplasms, Osteitis Deformans

NCT01808573 2021-06-11

NALA

Phase 3 Completed

621 enrolled 21 charts 2 FDA

Breast

HER2+ Metastatic Breast Cancer (MBC)

NCT00073528 2021-02-24

Study Comparing Lapatinib (GW572016) And Letrozole Versus Letrozole In Subjects With Advanced Or Metastatic Breast Cancer

Phase 3 Completed

1,286 enrolled 41 charts

Breast

Breast Neoplasms

NCT00390455 2019-12-20

Fulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-Positive

Phase 3 Completed

295 enrolled 18 charts

Breast

Breast Neoplasms

NCT00968968 2019-06-10

Continued HER2 Suppression With Lapatinib Plus Trastuzumab Versus Trastuzumab Alone

Phase 3 Terminated

37 enrolled 11 charts

Tumor-Agnostic

Carcinoma, Neoplasms

NCT00820222 2019-04-02

Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in ErbB2 (HER2) Positive Metastatic Breast Cancer

Phase 3 Completed

540 enrolled 18 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT00829166 2016-10-31

EMILIA

Phase 3 Completed

991 enrolled 26 charts

Breast

Breast Neoplasms

NCT00320385 2016-02-26

Lapatinib In Combination With Trastuzumab Versus Lapatinib Monotherapy In Subjects With HER2-positive Metastatic Breast Cancer

Phase 3 Completed

296 enrolled 13 charts

Breast

Breast Neoplasms

NCT00075270 2015-05-06

Paclitaxel With / Without GW572016 (Lapatinib) As First Line Therapy For Women With Advanced Or Metastatic Breast Cancer

Phase 3 Completed

580 enrolled 27 charts

Breast

Breast Neoplasms

NCT00374322 2014-08-18

Tykerb Evaluation After Chemotherapy (TEACH): Lapatinib Versus Placebo In Women With Early-Stage Breast Cancer

Phase 3 Completed

3,166 enrolled 18 charts

Breast

Breast Neoplasms

NCT00424255 2014-07-18

Study Of Adjuvant Lapatinib In High-Risk Head And Neck Cancer Subjects After Surgery

Phase 3 Completed

688 enrolled 19 charts

Head & Neck

Head and Neck Neoplasms

NCT00486954 2013-06-20

Lapatinib in Combination With Weekly Paclitaxel in Patients With ErbB2 Amplified Advanced Gastric Cancer

Phase 3 Completed

273 enrolled 53 charts

Gastrointestinal

Neoplasms, Stomach Neoplasms