NCT02581137 2026-03-18
Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion
National Cancer Institute (NCI)
Phase 2 Active not recruiting
Clinical Trials
55 trialsNCT02946996 2026-03-05
Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
Medical University of South Carolina
Phase 2 Terminated
NCT04850846 2026-02-09
Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma
Dana-Farber Cancer Institute
Phase 2 Active not recruiting
NCT02365597 2026-01-30
An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer
Janssen Research & Development, LLC
Phase 2 Active not recruiting
NCT03109847 2025-12-11
Metformin to Mitigate Sequelae of Radioactive Iodine Treatment for Thyroid Cancers
Thomas Jefferson University
Phase 2 Terminated
NCT02186847 2025-10-09
Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer
NRG Oncology
Phase 2 Completed
NCT02500147 2025-07-02
Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)
Columbia University
Phase 4 Terminated
NCT03109873 2025-04-30
Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer
Thomas Jefferson University
Phase EARLY_PHASE1 Completed
NCT01905046 2025-04-13
Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer
Alliance for Clinical Trials in Oncology
Phase 3 Active not recruiting
NCT02035787 2024-12-18
Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients
UNC Lineberger Comprehensive Cancer Center
Phase 2 Completed
NCT03800602 2024-09-05
Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer
Emory University
Phase 2 Completed
NCT02431676 2024-08-28
SPIRIT
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 2 Completed
NCT00984490 2024-02-01
Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery
Vanderbilt-Ingram Cancer Center
Phase NA Terminated
NCT01101438 2023-09-13
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer
Canadian Cancer Trials Group
Phase 3 Completed
NCT02949700 2023-06-29
Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma
Baylor College of Medicine
Phase 1/2 Completed
NCT02028221 2023-06-27
Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk
University of Arizona
Phase 2 Completed
NCT00930579 2022-10-20
Pre-Surgical Study: Effect of Metformin on Breast Cancer Proliferation
Columbia University
Phase 2 Completed
NCT02176161 2022-10-18
Metformin Prostate Cancer Adjuvant Trial
NYU Langone Health
Phase 2 Completed
NCT02531308 2022-09-28
DLBCL
Rush University Medical Center
Phase 2 Terminated
NCT02614859 2022-03-29
BIMET-1
Fox Chase Cancer Center
Phase 2 Completed
NCT01482286 2022-03-15
PULSE
Pennington Biomedical Research Center
Phase 3 Terminated
NCT00038727 2021-12-28
DPPOS
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Phase 3 Unknown
NCT01666730 2021-08-10
Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer
Case Comprehensive Cancer Center
Phase 2 Completed
NCT01310231 2021-04-14
A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast Cancer
Ozmosis Research Inc.
Phase 2 Completed
NCT02635386 2021-01-29
EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)
Woman's
Phase 3 Completed
NCT02495103 2021-01-26
Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma
National Institutes of Health Clinical Center (CC)
Phase 1/2 Terminated
NCT03048500 2020-10-14
Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Northwestern University
Phase 2 Unknown
NCT01627067 2020-06-19
Exemestane-RAD001-Metformin
M.D. Anderson Cancer Center
Phase 2 Terminated
NCT02325401 2020-06-11
Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma
University of Cincinnati
Phase 1 Completed
NCT01302379 2020-06-05
Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors
University of California, San Diego
Phase NA Completed
NCT01717482 2020-03-10
Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer
Mayo Clinic
Phase 2 Terminated
NCT03117517 2020-03-02
Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome
Khyber Medical University Peshawar
Phase EARLY_PHASE1 Completed
NCT02285855 2020-01-06
Metformin in Non Small Cell Lung Cancer (NSCLC)
M.D. Anderson Cancer Center
Phase 2 Terminated
NCT01312467 2019-03-05
Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI
National Cancer Institute (NCI)
Phase 2 Completed
NCT01849276 2019-01-31
Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML
Northwestern University
Phase 1 Terminated
NCT01578551 2018-12-19
Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Phase 2 Terminated
NCT01579812 2018-05-25
Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients
University of Michigan Rogel Cancer Center
Phase 2 Completed
NCT01620593 2018-05-23
Castration Compared to Castration Plus Metformin as First Line Treatment for Patients With Advanced Prostate Cancer
The University of Texas Health Science Center at San Antonio
Phase 2 Completed
NCT02019979 2018-05-04
METRO
Beth Israel Medical Center
Phase 2 Terminated
NCT00151411 2018-03-21
Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)
Milton S. Hershey Medical Center
Phase 2 Completed
NCT01433913 2018-01-10
Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
National Cancer Institute (NCI)
Phase 2 Completed
NCT02376166 2017-12-22
M-RePoRT
Icahn School of Medicine at Mount Sinai
Phase NA Completed
NCT02815397 2017-11-17
DLBCL
Rush University Medical Center
Phase 2 Terminated
NCT02360059 2017-08-17
Metformin for Reduction of Paclitaxel-Related Neuropathy in Patients With Breast Cancer
M.D. Anderson Cancer Center
Phase 2 Terminated
NCT00703508 2017-06-14
Pharmacogenetics of Metformin Action in PCOS
Virginia Commonwealth University
Phase NA Completed
NCT01215032 2017-05-15
Metformin in Castration-Resistant Prostate Cancer
Massachusetts General Hospital
Phase 2 Terminated
NCT01632020 2016-07-11
Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth
University of Arkansas
Phase 2 Terminated
NCT02498522 2016-05-19
MIP
Ain Shams University
Phase EARLY_PHASE1 Completed
NCT00283816 2015-05-15
Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy
University of Rochester
Phase 3 Completed
NCT00714233 2015-05-15
Treatment of Adolescent Polycystic Ovary Syndrome (PCOS)
University of Rochester
Phase 3 Completed