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NCT02159066 2024-03-05

LOGIC-2

Phase 2 Completed

158 enrolled 40 charts

Melanoma

NCT02340780 2023-08-22

Buparlisib in Patients With Relapsed and Refractory Chronic Lymphocytic Leukemia

Phase 2 Completed

14 enrolled 9 charts

LymphoidOther hematologic neoplasm

Leukemia, Lymphocytic, Chronic, B-Cell

NCT02000882 2022-02-07

STAR Cape+BKM120 MBC With Brain Met

Phase 2 Completed

10 enrolled 11 charts

Brain Neoplasms, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01695473 2021-01-13

Neoadjuvant BKM120 in High-risk Prostate Cancer

Phase 2 Terminated

11 enrolled 8 charts

Prostatic Neoplasms

NCT01629615 2020-10-28

A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast Cancer

Phase 2 Completed

50 enrolled 10 charts

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT01610284 2020-08-25

BELLE-2

Phase 3 Completed

1,147 enrolled 20 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01349660 2020-06-17

Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme

Phase 1/2 Completed

88 enrolled 13 charts

Glioblastoma

NCT01816594 2019-11-14

NeoPHOEBE

Phase 2 Completed

50 enrolled 23 charts

Breast Neoplasms

NCT01289041 2019-05-30

BKM120 as Second-line Therapy for Advanced Endometrial Cancer

Phase 2 Completed

70 enrolled 8 charts

Advanced Endometrial Cancer

NCT01339052 2019-03-19

Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma

Phase 2 Completed

65 enrolled 30 charts

Brain Neoplasms, Glioblastoma

NCT01487265 2019-03-06

Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to Erlotinib

Phase 2 Completed

37 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung

NCT01633060 2019-01-30

BELLE-3

Phase 3 Terminated

432 enrolled 20 charts

Breast Neoplasms, Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT02303041 2019-01-29

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Phase 2 Terminated

10 enrolled 11 charts

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell, Skin Neoplasms

NCT01790932 2019-01-23

BKM120 For Triple Negative Breast Cancer

Phase 2 Completed

50 enrolled 8 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01833169 2018-10-19

SIGNATURE

Phase 2 Completed

146 enrolled 17 charts

Other hematologic neoplasm

Neoplasms, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT01923168 2018-09-14

Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women

Phase 2 Completed

340 enrolled 39 charts

Breast Neoplasms

NCT01852292 2018-07-24

Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy

Phase 2 Terminated

157 enrolled 22 charts

Squamous Cell Carcinoma of Head and Neck, Neoplasm Metastasis, Recurrence

NCT01870726 2018-05-30

Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent Glioblastoma

Phase 1/2 Terminated

43 enrolled 22 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT02301364 2017-10-19

Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)

Phase 2 Completed

4 enrolled 11 charts

Lymphoma, Recurrence

NCT01385293 2017-05-19

BKM120 in Metastatic Castration-resistant Prostate Cancer

Phase 2 Terminated

30 enrolled 11 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT01572727 2017-03-09

BELLE-4

Phase 2/3 Completed

416 enrolled 11 charts

Breast Neoplasms, Neoplasm Metastasis, Hereditary Sensory and Autonomic Neuropathies

NCT01132664 2016-08-17

Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer

Phase 1/2 Terminated

72 enrolled 15 charts

Brain Neoplasms, Breast Neoplasms

NCT01297491 2016-03-11

BASALT-1

Phase 2 Completed

63 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung