Clinical Trials Browser

INDUSTRY × Has results × Temozolomide × Clear all

NCT05440786 2026-03-12

CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Phase 2 Active not recruiting

46 enrolled 19 charts

Neoplasm Metastasis, Sarcoma, Ewing

NCT04238819 2026-03-02

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Phase 1/2 Completed

47 enrolled 36 charts

Diffuse Intrinsic Pontine Glioma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Rhabdoid Tumor

NCT02667587 2025-06-18

CheckMate548

Phase 3 Completed

716 enrolled 15 charts

Brain Neoplasms

NCT02655601 2025-06-08

BMX-HGG

Phase 1/2 Completed

177 enrolled 34 charts

Astrocytoma, Glioblastoma, Glioma

NCT04421378 2024-12-16

A Study of Selinexor in Combination With Standard of Care Therapy for Newly Diagnosed or Recurrent Glioblastoma

Phase 1/2 Terminated

74 enrolled 23 charts

Glioblastoma

NCT01127178 2024-10-10

Study of Poly (ADP-Ribose) Polymerase (PARP) Inhibitor E7016 in Combination With Temozolomide in Subjects With Advanced Solid Tumors

Phase 1 Terminated

12 enrolled 13 charts

Other solid neoplasm

Solid Tumors

NCT00589875 2024-04-03

BrTK02

Phase 2 Completed

52 enrolled 10 charts

Astrocytoma, Glioblastoma, Glioma

NCT02052648 2024-03-27

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

Phase 1/2 Completed

160 enrolled 21 charts

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT02315534 2023-11-15

A Study of BBI608 in Combination With Temozolomide in Adult Patients With Recurrent or Progressed Glioblastoma

Phase 1/2 Completed

34 enrolled 18 charts

Glioblastoma, Glioma

NCT02573324 2023-05-11

Intellance1

Phase 3 Completed

691 enrolled 28 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT03495921 2023-04-26

VITA

Phase 3 Terminated

32 enrolled 13 charts

Neoplasms, Neoplasms by Histologic Type, Neoplasms, Connective Tissue, Sarcoma, Sarcoma, Ewing, Neoplasms, Connective and Soft Tissue, Neoplasms, Bone Tissue, Neuroectodermal Tumors, Primitive, Peripheral, Rare Diseases

NCT02617589 2023-03-28

CheckMate 498

Phase 3 Completed

560 enrolled 14 charts

Brain Neoplasms

NCT02511132 2022-12-22

A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma

Phase 2 Completed

22 enrolled 13 charts

Sarcoma, Sarcoma, Ewing

NCT02288897 2022-01-19

PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma

Phase 3 Terminated

20 enrolled 13 charts

Melanoma, Recurrence

NCT03034135 2021-09-13

Safety, Tolerability and Efficacy of Disulfiram and Copper Gluconate in Recurrent Glioblastoma

Phase 2 Completed

23 enrolled 11 charts

Glioblastoma

NCT03419403 2021-04-14

UNITE Study: Understanding New Interventions With GBM ThErapy

Phase 3 Terminated

40 enrolled 16 charts

Glioblastoma, Neoplasms

NCT02340156 2021-03-03

Phase II Study of Combined Temozolomide and SGT-53 for Treatment of Recurrent Glioblastoma

Phase 2 Terminated

1 enrolled 8 charts

Glioblastoma

NCT02698410 2020-10-01

ATLANT

Phase 2 Completed

40 enrolled 17 charts

Neuroendocrine Tumors

NCT00402116 2020-08-06

Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patients

Phase 1/2 Completed

72 enrolled 19 charts

Glioblastoma, Gliosarcoma

NCT01390948 2020-08-06

A Study of Bevacizumab (Avastin) in Combination With Temozolomide (TMZ) and Radiotherapy in Paediatric and Adolescent Participants With High-Grade Glioma

Phase 2 Completed

124 enrolled 23 charts

Glioma

NCT01790503 2020-06-30

A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma

Phase 1/2 Completed

65 enrolled 26 charts

Glioblastoma

NCT02343406 2020-05-22

INTELLANCE-2

Phase 2 Completed

266 enrolled 23 charts

Brain Neoplasms, Glioblastoma

NCT01704287 2020-05-18

KEYNOTE 002

Phase 2 Completed

540 enrolled 20 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Melanoma

NCT02231762 2019-05-06

SONNET

Phase 2 Completed

57 enrolled 20 charts

EndocrineGastrointestinalNET

Gastroenteropancreatic Neuroendocrine Tumors

NCT00977431 2019-02-18

Open Label Trial to Explore Safety of Combining Afatinib (BIBW 2992) and Radiotherapy With or Without Temozolomide in Newly Diagnosed Glioblastoma Multiform

Phase 1 Completed

36 enrolled 16 charts

Glioblastoma

NCT01284335 2019-01-10

A Safety Study in Participants With Advanced Solid Tumors

Phase 1 Terminated

234 enrolled 23 charts

Neoplasm Metastasis

NCT00960063 2018-08-27

A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006)

Phase 1 Terminated

4 enrolled 8 charts

CNSGenitourinarySarcoma

Bone Neoplasms, Carcinoma, Renal Cell, Neoplasms, Neuroblastoma

NCT00804908 2018-06-06

A Study Evaluating Efficacy of ABT-888 in Combination With Temozolomide in Metastatic Melanoma

Phase 2 Completed

346 enrolled 15 charts

Melanoma, Skin Neoplasms

NCT00943826 2017-09-25

A Study of Bevacizumab (Avastin®) in Combination With Temozolomide and Radiotherapy in Participants With Newly Diagnosed Glioblastoma

Phase 3 Completed

921 enrolled 14 charts

Glioblastoma

NCT00638963 2017-06-14

STOP

Phase 2 Terminated

6 enrolled 9 charts

Brain Neoplasms, Breast Neoplasms, Neoplasms, Second Primary

NCT00686725 2017-06-14

Standard Temodal (Temozolomide) Regimen Versus Standard Regimen Plus Early Postsurgery Temodal for Newly Diagnosed Glioblastoma Multiforme (Study P05572)

Phase 4 Completed

99 enrolled 15 charts

Glioblastoma

NCT00266812 2017-06-08

Safety and Tolerability of Low-Dose Temozolomide During Whole Brain Radiation in Patients With Cerebral Metastases From Non-Small-Cell Lung Cancer (Study P04071)(TERMINATED)

Phase 2 Terminated

35 enrolled 7 charts

Carcinoma, Non-Small-Cell Lung

NCT00392171 2017-06-07

The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601)

Phase 2 Completed

120 enrolled 6 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT00632203 2017-06-07

Study of Maintenance Temozolomide Versus Observation in Stable or Responding Stage III/IV Non-Small Cell Lung Cancer Patients (Study P05146)

Phase 2 Terminated

53 enrolled 10 charts

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Carcinoma, Squamous Cell, Carcinoma, Large Cell

NCT00684567 2017-06-07

Temozolomide Phase II Clinical Study in Patients With Newly Diagnosed Glioblastoma Multiforme (Study P04661)(COMPLETED)

Phase 2 Completed

30 enrolled 12 charts

Glioblastoma

NCT00687323 2017-06-07

TALL

Phase 2 Completed

47 enrolled 12 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT00091572 2017-06-06

Temozolomide Versus Dacarbazine in Stage IV Metastatic Melanoma (Study P03267)

Phase 3 Completed

859 enrolled 11 charts

Melanoma

NCT00813943 2017-01-30

CORE

Phase 2 Completed

265 enrolled 20 charts

Glioblastoma

NCT00967330 2015-11-20

A Study of Avastin (Bevacizumab) and Irinotecan Versus Temozolomide Radiochemistry in Patients With Glioblastoma

Phase 2 Completed

182 enrolled 18 charts

Glioblastoma

NCT00704808 2015-09-09

Post Marketing Surveillance: Newly Diagnosed Glioblastoma Multiforme Treated With Radiotherapy/Temozolomide and Adjuvant Temozolomide (Study P04739)

180 enrolled 6 charts

Glioblastoma

NCT00725010 2015-09-09

Temozolomide in Concomitant Radiochemotherapy Followed by Sequential Temozolomide Chemotherapy - Observational Program (Study P04816)

64 enrolled 7 charts

Glioblastoma

NCT02343081 2015-04-02

Bioequivalence Study of Temozolomide in Patients With Primary Tumors of the Central Nervous System

Phase 4 Completed

24 enrolled 13 charts

Brain Neoplasms

NCT00723827 2015-01-30

Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)

682 enrolled 10 charts

Astrocytoma, Glioblastoma, Glioma

NCT01115491 2014-12-08

A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme

Phase 2 Completed

32 enrolled 11 charts

Glioblastoma

NCT00761280 2014-11-14

SAPPHIRE

Phase 3 Terminated

27 enrolled 28 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Neoplasms

NCT00404495 2012-04-18

Combination of Irinotecan and Temozolomide in Children With Brain Tumors.

Phase 2 Completed

83 enrolled 12 charts

Glioma, Medulloblastoma