Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma
Phase 2/3 Completed
159 enrolled 17 charts
ARETHUSA
Phase 2 Completed
107 enrolled 14 charts
A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma
Phase 1/2 Completed
47 enrolled 36 charts
STEAM
Phase 1 Completed
71 enrolled 18 charts
Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma
Phase 2 Completed
21 enrolled 12 charts
18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy
Phase 2 Completed
91 enrolled 14 charts
Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma
Phase 1 Completed
21 enrolled 12 charts
Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastoma
Phase 2 Completed
30 enrolled 12 charts
18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy
Phase 2 Completed
43 enrolled 19 charts
MIRAGE
Phase 3 Completed
749 enrolled 15 charts
Temozolomide Chronotherapy for High Grade Glioma
Phase 2 Completed
42 enrolled 19 charts
CheckMate548
Phase 3 Completed
716 enrolled 15 charts
BMX-HGG
Phase 1/2 Completed
177 enrolled 34 charts
Phase I Dose-Escalation Study Of Azacitidine In Combination With Temozolomide
Phase 1 Completed
27 enrolled 7 charts
Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma
Phase 1/2 Completed
35 enrolled 16 charts
ABT-888 and Temozolomide for Metastatic Breast Cancer and BRCA1/2 Breast Cancer
Phase 2 Completed
63 enrolled 11 charts
Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Phase 1 Completed
33 enrolled 15 charts
BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations
Phase 1/2 Completed
67 enrolled 18 charts
Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphoma
Phase 1 Completed
30 enrolled 19 charts
Temozolomide and Radiation Therapy in Treating Patients With Gliomas
Phase 2 Completed
136 enrolled 9 charts
Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed Glioblastoma
Phase 2 Completed
36 enrolled 11 charts
BrTK02
Phase 2 Completed
52 enrolled 10 charts
Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors
Phase 1/2 Completed
160 enrolled 21 charts
Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma
Phase 2/3 Completed
101 enrolled 15 charts
Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine Tumors
Phase 2 Completed
20 enrolled 15 charts
A Study of BBI608 in Combination With Temozolomide in Adult Patients With Recurrent or Progressed Glioblastoma
Phase 1/2 Completed
34 enrolled 18 charts
VIT-B
Phase 1 Completed
13 enrolled 6 charts
MPACT Study to Compare Effects of Targeted Drugs on Tumor Gene Variations
Phase 2 Completed
208 enrolled 27 charts
TMZ + Olaparib for MGMT Hypermethylated Colorectal Cancer
Phase 2 Completed
11 enrolled 13 charts
Medical Treatment of "High-Risk" Neurofibromas
Phase 2 Completed
9 enrolled 9 charts
Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Multiforme
Phase 3 Completed
562 enrolled 11 charts
Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy
Phase 3 Completed
35 enrolled 13 charts
Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors
Phase 1 Completed
26 enrolled 16 charts
Low Dose Radiation Therapy for Glioblastoma Multiforme
Phase 2 Completed
31 enrolled 11 charts
Temozolomide and Radiation Therapy in Treating Patients With Brain Metastasis Secondary to Non-Small Cell Lung Cancer
Phase 2 Completed
26 enrolled 8 charts
Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma
Phase 1/2 Completed
65 enrolled 21 charts
ELEVATE
Phase 2 Completed
64 enrolled 17 charts
Intellance1
Phase 3 Completed
691 enrolled 28 charts
CheckMate 498
Phase 3 Completed
560 enrolled 14 charts
RAD0102
Phase 2 Completed
25 enrolled 8 charts
Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas
Phase 2 Completed
118 enrolled 8 charts
A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma
Phase 2 Completed
22 enrolled 13 charts
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma
Phase 2 Completed
73 enrolled 12 charts
Vorinostat, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Phase 1/2 Completed
125 enrolled 12 charts
Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed by Surgery
Phase 2 Completed
47 enrolled 12 charts
Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma
Phase 2 Completed
261 enrolled 10 charts
Temozolomide and Sorafenib in Treating Patients With Metastatic or Unresectable Melanoma
Phase 2 Completed
169 enrolled 10 charts
Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma
Phase 2 Completed
80 enrolled 11 charts
O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain Stem Tumors
Phase 2 Completed
41 enrolled 9 charts
Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme
Phase 2 Completed
178 enrolled 23 charts