Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies
Phase 1/2 Terminated
19 enrolled 11 charts
A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)
Phase 1/2 Completed
341 enrolled 28 charts
MORPHEUS HR+BC
Phase 1/2 Completed
144 enrolled 25 charts
High-Risk Skin Cancers With Atezolizumab Plus NT-I7
Phase 1/2 Terminated
31 enrolled 12 charts
A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)
Phase 1/2 Completed
12 enrolled 18 charts
Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers
Phase 1/2 Terminated
112 enrolled 28 charts
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)
Phase 1/2 Completed
110 enrolled 27 charts
Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell Carcinoma
Phase 1/2 Terminated
31 enrolled 19 charts
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411
Phase 1/2 Terminated
54 enrolled 30 charts
MEKiAUTO
Phase 1/2 Terminated
27 enrolled 12 charts
Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead In
Phase 1/2 Completed
89 enrolled 16 charts
A Study of ASP2215 (Gilteritinib) Combined With Atezolizumab in Patients With Relapsed or Treatment Refractory FMS-like Tyrosine Kinase (FLT3) Mutated Acute Myeloid Leukemia (AML)
Phase 1/2 Completed
11 enrolled 18 charts
Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung Cancer
Phase 1/2 Terminated
3 enrolled 8 charts
A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma
Phase 1/2 Completed
24 enrolled 18 charts
Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab for Maintenance Treatment in Subjects With Acute Myeloid Leukemia (AML)
Phase 1/2 Terminated
1 enrolled 6 charts
Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult Patients
Phase 1/2 Terminated
9 enrolled 7 charts
ZUMA-6
Phase 1/2 Completed
37 enrolled 28 charts
Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast Cancer
Phase 1/2 Completed
28 enrolled 12 charts
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic Colorectal Cancer (Morpheus-CRC)
Phase 1/2 Terminated
96 enrolled 24 charts
FIDES-02
Phase 1/2 Completed
95 enrolled 25 charts
Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer
Phase 1/2 Terminated
1 enrolled 6 charts
Safety, Preliminary Efficacy and PK of Isatuximab (SAR650984) Alone or in Combination With Atezolizumab in Patients With Advanced Malignancies
Phase 1/2 Terminated
107 enrolled 30 charts
PROPEL
Phase 1/2 Terminated
162 enrolled 21 charts
A Study of Cobimetinib Administered as Single Agent and in Combination With Venetoclax, With or Without Atezolizumab, in Participants With Relapsed and Refractory Multiple Myeloma
Phase 1/2 Completed
49 enrolled 24 charts
A Study Evaluating the Safety and Efficacy of Atezolizumab in Combination With Obinutuzumab Plus Lenalidomide in Patients With Relapsed or Refractory Follicular Lymphoma
Phase 1/2 Completed
38 enrolled 20 charts
Safety and Pharmacology Study of Atezolizumab Alone and in Combination With Bacille Calmette-Guérin (BCG) in High-Risk Non-Muscle-Invasive Bladder Cancer (NMIBC) Participants
Phase 1/2 Terminated
24 enrolled 18 charts
AdORN
Phase 1/2 Completed
18 enrolled 15 charts
Atezolizumab and Cobimetinib or Idasanutlin in Participants With Stage IV or Unresectable Recurrent Estrogen Receptor Positive Breast Cancer
Phase 1/2 Terminated
12 enrolled 13 charts
A Study of Atezolizumab in Combination With Either Obinutuzumab Plus Bendamustine or Obinutuzumab Plus (+) Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Participants With Follicular Lymphoma (FL) or Rituximab + CHOP in Participants With Diffuse Large B-Cell Lymphoma (DLBCL)
Phase 1/2 Completed
91 enrolled 27 charts
A Study Evaluating Safety and Efficacy of Obinutuzumab, Polatuzumab Vedotin (Pola), and Atezolizumab (Atezo) in Participants With Relapsed or Refractory Follicular Lymphoma (FL) and Rituximab, Atezo, and Pola in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Phase 1/2 Completed
36 enrolled 22 charts
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) in Pediatric and Young Adult Participants With Solid Tumors
Phase 1/2 Terminated
87 enrolled 41 charts
DARZALEX
Phase 1/2 Completed
100 enrolled 24 charts
A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC
Phase 1/2 Terminated
3 enrolled 8 charts