Clinical Trials

19 enrolled 11 charts

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Lung Neoplasms

NCT03747419 2025-10-31

Avelumab and Radiation in Muscle-Invasive Bladder Cancer

14 enrolled 14 charts

Urinary Bladder Neoplasms

NCT04887831 2025-09-08

PRESERVE3

92 enrolled 24 charts

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT03747484 2025-03-06

Gene-Modified Immune Cells (FH-MCVA2TCR) in Treating Patients With Metastatic or Unresectable Merkel Cell Cancer

7 enrolled 15 charts

Dermatologic

Neoplasm Metastasis, Carcinoma, Merkel Cell

NCT04322643 2025-02-25

Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial Carcinoma

4 enrolled 10 charts

Carcinoma, Transitional Cell

NCT03636503 2025-02-06

Rituximab + Immunotherapy in Follicular Lymphoma

24 enrolled 25 charts

Lymphoid

Lymphoma, Lymphoma, Follicular

NCT04871529 2024-12-30

Testing the Addition of an Anti-Cancer Immunotherapy Drug, Avelumab, to Gemcitabine and Carboplatin Chemotherapy Prior to Surgery in Muscle Invasive Urinary Tract Cancer vs. Surgery Alone in Patients Who Are Not Able to Receive Cisplatin Therapy (SWOG GAP TRIAL)

6 enrolled 12 charts

Urinary Bladder Neoplasms

NCT03329248 2024-12-12

QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

6 enrolled 15 charts

Pancreatic Neoplasms

NCT03563157 2024-12-11

QUILT 3.071: NANT Colorectal Cancer (CRC) Vaccine

2 enrolled 13 charts

Colorectal Neoplasms

NCT02994953 2024-09-20

COMBO

52 enrolled 34 charts

Other solid neoplasm

Advanced Solid Tumors

NCT02875613 2024-08-28

Avelumab for Recurrent/Metastatic Nasopharyngeal Cancer

6 enrolled 8 charts

Head & Neck

Nasopharyngeal Neoplasms, Epstein-Barr Virus Infections

NCT03586869 2024-08-27

QUILT-3.080: NANT Pancreatic Cancer Vaccine

3 enrolled 13 charts

Pancreatic Neoplasms

NCT03050554 2024-08-09

SBRT Combined With Avelumab (Anti-PD-L1) for Management of Early Stage Non-Small Cell Lung Cancer (NSCLC)

2 enrolled 6 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT03387085 2024-08-09

QUILT-3.067: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With TNBC Who Have Progressed on or After Standard-of-care Therapy.

9 enrolled 18 charts

Breast

Triple Negative Breast Neoplasms

NCT03853317 2024-08-09

QUILT-3.063: A Study of N-803, haNK and Avelumab in Patients With Merkel Cell Carcinoma That Has Progressed After Checkpoint Therapy

9 enrolled 13 charts

Dermatologic

Carcinoma, Merkel Cell

NCT03387111 2024-08-05

QUILT-3.090: NANT Squamous Cell Carcinoma (SCC) Vaccine: Subjects With SCC Who Have Progressed

4 enrolled 14 charts

Tumor-Agnostic

Carcinoma, Squamous Cell

NCT03770455 2024-07-09

Avelumab Plus 2nd-generation ADT in African American Subjects With mCRPC

8 enrolled 7 charts

Metastatic Castration-resistant Prostate Cancer

NCT03451825 2024-06-24

Phase I/II Study of Avelumab in Pediatric Cancer Participants

21 enrolled 21 charts

CNSLymphoid

Lymphoma, Central Nervous System Neoplasms

NCT03136406 2024-06-11

QUILT-3.039: NANT Pancreatic Cancer Vaccine: Combination Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

3 enrolled 9 charts

Pancreatic Neoplasms

NCT03387098 2024-05-22

QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

4 enrolled 9 charts

Pancreatic Neoplasms

NCT03472560 2024-04-09

A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF)

61 enrolled 26 charts

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasms

NCT03386929 2023-12-18

SPRING

15 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung

NCT03330405 2023-10-13

Javelin Parp Medley: Avelumab Plus Talazoparib In Locally Advanced Or Metastatic Solid Tumors

BreastGynecologicThoracic

223 enrolled 50 charts

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Recurrence

NCT03565991 2023-09-25

Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid Tumors

202 enrolled 31 charts

Hereditary Sensory and Autonomic Neuropathies

NCT03317496 2023-08-29

Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignancies

67 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT02584634 2023-07-07

Javelin Lung 101

43 enrolled 40 charts

Carcinoma, Non-Small-Cell Lung

NCT05249569 2023-05-03

Study of Bavituximab, Axitinib, and Avelumab in Advanced Hepatocellular Carcinoma

1 enrolled 4 charts

Carcinoma, Hepatocellular

NCT03502681 2022-07-01

A Study Combining Eribulin Mesylate With Avelumab in Cisplatin Ineligible Metastatic Urothelial Cell Cancer Patients

6 enrolled 12 charts

Metastatic Urothelial Cell Cancer

NCT04150562 2022-05-17

Avelumab (Bavencio) With IL-15 in Subjects With Clear-Cell Renal Carcinoma

2 enrolled 13 charts

Carcinoma, Renal Cell

NCT03074318 2022-04-29

Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery

35 enrolled 21 charts

Sarcoma

Leiomyosarcoma, Liposarcoma

NCT03000179 2022-04-14

Safety and Efficacy of Avelumab in Small Intestinal Adenocarcinoma

8 enrolled 12 charts

Tumor-Agnostic

Adenocarcinoma

NCT02584829 2022-03-22

Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma

8 enrolled 16 charts

Dermatologic

Carcinoma, Merkel Cell

NCT03050814 2021-12-20

Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004

30 enrolled 15 charts

Turcot syndrome, Colorectal Neoplasms

NCT04052204 2021-10-14

Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors

3 enrolled 12 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT02952586 2021-09-22

Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100)

Phase 3 Terminated

697 enrolled 26 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT02349633 2021-06-10

Study For Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)

65 enrolled 61 charts

Carcinoma, Non-Small-Cell Lung

NCT03910439 2021-05-12

Avelumab in Combination With Hypofractionated Radiotherapy in Patients With Relapsed Refractory Multiple Myeloma

4 enrolled 12 charts

Plasma cell

Multiple Myeloma

NCT02951156 2020-12-17

Javelin DLBCL

Phase 3 Terminated

29 enrolled 24 charts

Lymphoid

Lymphoma, Large B-Cell, Diffuse

NCT03312114 2020-11-12

Anti-PD-L1 and SAbR for Ovarian Cancer

5 enrolled 4 charts

Gynecologic

Fallopian Tube Neoplasms

NCT02953561 2020-10-22

Avelumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia

Other hematologic neoplasm

19 enrolled 11 charts

Leukemia, Myeloid, Acute

NCT03498196 2020-08-24

A Window of Opportunity Trial: Avelumab in Non-metastatic Muscle Invasive Bladder Cancer

1 enrolled 10 charts

Non-Muscle Invasive Bladder Neoplasms, Urinary Bladder Neoplasms

NCT02718417 2020-07-14

JAVELIN OVARIAN 100

Phase 3 Terminated

998 enrolled 39 charts

Gynecologic

Ovarian Neoplasms

NCT03344172 2020-05-14

17-134

32 enrolled 14 charts