NCT03915951 2025-11-17An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung CancerPfizerPhase 2 Completed98 enrolled 18 charts 1 FDA
NCT03898908 2025-05-21EBRAIN-MELGrupo Español Multidisciplinar de MelanomaPhase 2 Completed48 enrolled 24 charts
NCT03864042 2024-09-27Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid TumorsPfizerPhase 1 Completed56 enrolled 158 charts
NCT01894672 2024-07-16BRAF Inhibitor, LGX818, Utilizing a Pulsatile Schedule in Patients With Stage IV or Unresectable Stage III Melanoma Characterized by a BRAFV600 MutationMemorial Sloan Kettering Cancer CenterPhase 2 Completed7 enrolled 9 charts
NCT01543698 2024-03-13A Phase Ib/II Study of LGX818 in Combination With MEK162 in Adult Patients With BRAF Dependent Advanced Solid TumorsPfizerPhase 1/2 Completed189 enrolled 44 charts