NCT02601950 2025-06-22A Study of Tazemetostat in Adult Participants With Soft Tissue SarcomaIpsenPhase 2 Completed267 enrolled 25 charts 2 FDA
NCT04537715 2025-02-19Effects of Itraconazole and Rifampin on the Blood Tazemetostat LevelsIpsenPhase 1 Completed42 enrolled 39 charts
NCT02601937 2024-10-03EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial SarcomaIpsenPhase 1 Completed109 enrolled 25 charts
NCT01897571 2024-03-26Study of Tazemetostat as Single Agent in Solid Tumors or B-cell Lymphomas and in Combination With Prednisolone in DLBCLIpsenPhase 1/2 Completed400 enrolled 22 charts 2 FDA
NCT04762160 2024-03-25SYMPHONY-2, A Trial to Examine Combination of Tazemetostat With Rituximab in Subjects With Relapsed/Refractory Follicular LymphomaIpsenPhase 2 Terminated5 enrolled 7 charts
NCT03028103 2023-06-26Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor PatientsIpsenPhase 1 Completed32 enrolled 30 charts
NCT03456726 2022-12-16Study of Tazemetostat in Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma With EZH2 Gene MutationEisai Inc.Phase 2 Completed20 enrolled 17 charts
NCT03009344 2022-11-10A Study of Tazemetostat in Participants With Relapsed or Refractory B-cell Non-Hodgkin's LymphomaEisai Inc.Phase 1 Completed7 enrolled 31 charts
NCT02860286 2021-04-09Study of the EZH2 Inhibitor Tazemetostat in Malignant MesotheliomaEpizyme, Inc.Phase 2 Completed74 enrolled 23 charts