Clinical Trials

19 enrolled 11 charts

GenitourinaryThoracic

Urinary Bladder Neoplasms, Carcinoma, Renal Cell, Lung Neoplasms

NCT03590574 2026-03-16

Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma

20 enrolled 34 charts

Immunoblastic Lymphadenopathy, Lymphoma, T-Cell, Lymphoma, Large-Cell, Anaplastic

NCT02942264 2026-02-23

Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma

53 enrolled 22 charts

CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Recurrence, Gliosarcoma

NCT05269160 2026-02-17

Topical Dermaprazole for Radiation Dermatitis in Breast Cancer Patients (TOPAZ)

3 enrolled 8 charts

Breast Neoplasms, Radiodermatitis

NCT03101748 2026-02-12

Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer

34 enrolled 15 charts

Breast Neoplasms, Inflammatory Breast Neoplasms

NCT03559049 2026-02-12

Rucaparib and Pembrolizumab for Maintenance Therapy in Stage IV Non-Squamous Non-Small Cell Lung Cancer

25 enrolled 11 charts

Carcinoma, Non-Small-Cell Lung

NCT04809467 2026-02-04

topMIND

LymphoidOther hematologic neoplasm

54 enrolled 23 charts

Leukemia, Lymphoma, Non-Hodgkin, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell

NCT04913220 2026-02-04

A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201)

46 enrolled 22 charts

Melanoma

NCT04187404 2026-01-30

Spencer

70 enrolled 20 charts

CNSEndocrine

Paraganglioma, Pheochromocytoma, Adrenocortical Carcinoma

NCT03215030 2026-01-29

iinnovate-1

272 enrolled 67 charts

Plasma cell

Multiple Myeloma

NCT03553602 2026-01-29

BEACON

3 enrolled 7 charts

Genitourinary

Prostatic Neoplasms

NCT04157517 2026-01-29

A Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors

45 enrolled 44 charts

Melanoma, Neoplasms

NCT04856189 2026-01-29

Selinexor and Pembrolizumab for the Treatment of Cisplatin-Ineligible or Cisplatin-Refractory Locally Advanced or Metastatic Urothelial Carcinoma

4 enrolled 8 charts

Genitourinary

Carcinoma, Transitional Cell

NCT05070247 2026-01-22

A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors

BreastGastrointestinalGenitourinaryHead & NeckOther solid neoplasmThoracic

61 enrolled 29 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Kidney Neoplasms, Liver Neoplasms, Mesothelioma, Nasopharyngeal Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT04379518 2026-01-13

Rintatolimod and IFN Alpha-2b for the Treatment of COVID-19 in Cancer Patients

Other hematologic neoplasm

4 enrolled 30 charts

Hematologic Neoplasms

NCT04585815 2026-01-09

Study of Immunotherapy (Sasanlimab) in Combination With Targeted Therapies in People With Advanced Non-small Cell Lung Cancer (NSCLC) (Landscape 1011 Study)

34 enrolled 44 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT04240002 2026-01-05

A Study of Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Other hematologic neoplasm

9 enrolled 21 charts

Leukemia, Myeloid, Acute

NCT04203160 2025-12-31

Gemcitabine and Cisplatin With or Without CPI-613 as First Line Therapy for Patients With Advanced Unresectable Biliary Tract Cancer (BilT-04)

75 enrolled 17 charts

Gastrointestinal

Biliary Tract Neoplasms, Gallbladder Neoplasms, Cholangiocarcinoma

NCT05313009 2025-12-16

Tarlox and Sotorasib in Patients With KRAS G12C Mutations

5 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung

NCT05918055 2025-12-02

Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes

MyeloidOther hematologic neoplasm

3 enrolled 9 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03284957 2025-11-24

AMEERA-1

136 enrolled 60 charts

Breast Neoplasms

NCT02706353 2025-11-21

APX005M in Combination With Systemic Pembrolizumab in Patients With Metastatic Melanoma

34 enrolled 18 charts

Melanoma

NCT05525286 2025-11-17

CLAUDIO-01

31 enrolled 34 charts

Gastrointestinal

Neoplasm Metastasis, Pancreatic Neoplasms

NCT03519178 2025-11-14

A Study of PF-06873600 in People With Cancer

155 enrolled 44 charts

BreastGynecologic

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Breast Neoplasms, Male, Triple Negative Breast Neoplasms

NCT05194735 2025-11-10

Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors

GastrointestinalGynecologicThoracic

8 enrolled 12 charts

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Cholangiocarcinoma

NCT05617040 2025-11-10

Prime-boost Immunotherapeutic Trial in Men With Biochemical Recurrence After Definitive Local Therapy for Prostate Cancer

22 enrolled 11 charts

Genitourinary

Prostatic Neoplasms

NCT03837509 2025-11-04

INCB001158 Combined With Subcutaneous (SC) Daratumumab, Compared to Daratumumab SC, in Relapsed or Refractory Multiple Myeloma

15 enrolled 15 charts

Plasma cell

Multiple Myeloma, Recurrence

NCT04874194 2025-11-03

Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1

MyeloidOther hematologic neoplasm

24 enrolled 15 charts

Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Hematologic Neoplasms

NCT06069778 2025-10-31

Safety, Tolerability, and Efficacy of mFOLFIRINOX ± BNT321 as Adjuvant Therapy Following Curative Resection in Patients With Pancreatic Adenocarcinoma

1 enrolled 3 charts

Gastrointestinal

Pancreatic Neoplasms

NCT04972110 2025-10-30

ATTACC

156 enrolled 19 charts

Other solid neoplasm

Advanced Solid Tumor, Adult

NCT05469178 2025-10-29

A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 Gene

26 enrolled 13 charts

Carcinoma, Non-Small-Cell Lung

NCT04035434 2025-10-24

A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refractory B-Cell Malignancies (CARBON)

LymphoidOther hematologic neoplasm

93 enrolled 27 charts

Burkitt Lymphoma, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Lymphoma, B-Cell

NCT03901573 2025-10-22

High-Risk Skin Cancers With Atezolizumab Plus NT-I7

31 enrolled 12 charts

Melanoma, Carcinoma, Merkel Cell

NCT04582539 2025-10-22

LIMBER

Classical hematologyMyeloidPlasma cell

22 enrolled 28 charts

Anemia, Multiple Myeloma, Myelodysplastic Syndromes

NCT02711137 2025-10-21

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

BreastCNSGastrointestinalGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellThoracic

137 enrolled 31 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Ovarian Neoplasms, Pancreatic Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Lymphoma, Large B-Cell, Diffuse, Primary Myelofibrosis

NCT02959437 2025-10-21

Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)

70 enrolled 14 charts

Tumor-Agnostic

Neoplasm Metastasis

NCT04541017 2025-10-16

Testing the Addition of an Anti-cancer Drug, Hu5F9-G4 (Magrolimab), to the Usual Chemotherapy Treatment (Mogamulizumab) in T-Cell (a Type of Immune Cell) Lymphoma That Has Returned After Treatment or Does Not Respond to Treatment

8 enrolled 8 charts

Mycosis Fungoides, Sezary Syndrome

NCT04623216 2025-10-16

Sabatolimab as a Treatment for Patients With Acute Myeloid Leukemia and Presence of Measurable Residual Disease After Allogeneic Stem Cell Transplantation.

Other hematologic neoplasm

24 enrolled 16 charts

Leukemia, Myeloid, Acute, Neoplasm, Residual

NCT05198843 2025-10-03

Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body

1 enrolled 5 charts

Anatomic Stage IV Breast Cancer AJCC v8

NCT06018129 2025-09-25

A First-in-human Trial of GEN3017 in Hodgkin Lymphoma and Non-Hodgkin Lymphoma

9 enrolled 20 charts

Lymphoma, Non-Hodgkin

NCT03769181 2025-09-23

A Study of Isatuximab-based Therapy in Participants With Lymphoma

58 enrolled 37 charts

Lymphoma

NCT03446040 2025-09-18

An Investigational Immunotherapy Study of BMS-986258 Alone and in Combination With Nivolumab in Participants With Solid Cancers That Are Advanced or Have Spread

92 enrolled 31 charts

Advanced Cancer

NCT03838367 2025-09-09

Leronlimab (PRO 140) Combined With Carboplatin in Patients With Cytokine Chemokine Receptor 5 Positive (CCR5+) mTNBC

10 enrolled 15 charts

Triple Negative Breast Neoplasms

NCT02423902 2025-08-28

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Breast Cancer

9 enrolled 21 charts

Breast Neoplasms

NCT05109442 2025-08-20

Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers

112 enrolled 28 charts

Other solid neoplasm

Advanced Solid Tumor

NCT03330197 2025-08-12

A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

6 enrolled 14 charts

CNS

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma

NCT04611126 2025-08-12

T-cell Therapy in Combination With Nivolumab, Relatlimab and Ipilimumab for Patients With Metastatic Ovarian Cancer

6 enrolled 11 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT05032183 2025-08-11

Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

LymphoidOther hematologic neoplasm

4 enrolled 8 charts

Burkitt Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT02681302 2025-07-25

CPIT001