Clinical Trials Browser

Phase 1 × 10-propargyl-10-deazaaminopterin × Clear all

Hematologic Neoplasms

NCT03240211 2025-08-26

Study of Pembrolizumab Combined With Decitabine and Pralatrexate in PTCL and CTCL

Phase 1 Active not recruiting

37 enrolled

Lymphoid

Lymphoma, T-Cell

NCT02594267 2021-07-27

A Dose-Finding Study of Folotyn® (Pralatrexate Injection) Plus CHOP With Peripheral T-Cell Lymphoma (PTCL)

Phase 1 Completed

48 enrolled

Lymphoid

Lymphoma, T-Cell, Peripheral

NCT01789723 2020-01-23

Phase 1 Study of Fusilev to Prevent or Reduce Mucositis in Patients With Non-Hodgkin's Lymphoma Receiving Folotyn

Phase 1 Withdrawn

Lymphoid

Lymphoma, Non-Hodgkin

NCT01820091 2020-01-23

Phase 1 Study of Fusilev® to Prevent or Reduce Mucositis in Patients With Non-Small Cell Lung Cancer Receiving Folotyn®

Phase 1 Withdrawn

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT00554827 2020-01-03

Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Phase 1 Completed

55 enrolled

DermatologicLymphoid

Lymphoma, Mycosis Fungoides, Recurrence, Sezary Syndrome, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous

NCT01134341 2019-12-18

Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Phase 1 Completed

34 enrolled

DermatologicLymphoid

Mycosis Fungoides, Recurrence, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous, Lymphoma, Primary Cutaneous Anaplastic Large Cell

NCT01114282 2016-07-06

Phase I Bortezomib (VELCADE) in Combo With Pralatrexate in Relapsed/Refractory MM

Phase 1 Completed

11 enrolled

Plasma cell

Multiple Myeloma

NCT01532011 2016-07-04

Erlotinib in Combination With Pralatrexate in Advanced Malignancies

Phase 1 Completed

72 enrolled

Other solid neoplasm

Advanced Cancers

NCT00024245 2013-06-26

10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors

Phase 1 Completed

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

Clinical Trials

SPI-FOL-102

Study of Pembrolizumab Combined With Decitabine and Pralatrexate in PTCL and CTCL

A Dose-Finding Study of Folotyn® (Pralatrexate Injection) Plus CHOP With Peripheral T-Cell Lymphoma (PTCL)

Phase 1 Study of Fusilev to Prevent or Reduce Mucositis in Patients With Non-Hodgkin's Lymphoma Receiving Folotyn

Phase 1 Study of Fusilev® to Prevent or Reduce Mucositis in Patients With Non-Small Cell Lung Cancer Receiving Folotyn®

Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Phase I Bortezomib (VELCADE) in Combo With Pralatrexate in Relapsed/Refractory MM

Erlotinib in Combination With Pralatrexate in Advanced Malignancies

10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors