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1 trials

Recent Start date Enrollment

Phase 1/2 × Not yet recruiting × AZD 6244 × Clear all

Phase

Phase 2 4 Phase 1/2 1 Phase 1 1

Status

Terminated 3 Active not recruiting 3 Completed 2 Unknown 1 Recruiting 1 Not yet recruiting 1

Sponsor Class

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1 CNS 1

Conditions

Neurofibrosarcoma 1 Neurofibromatosis 1 1

Interventions

Bevacizumab 14 Injections 11 Drug Therapy 10 Gemcitabine 8 tislelizumab 6 irinotecan sucrosofate 6 Temozolomide 6 Paclitaxel 6 Oxaliplatin 6 Cyclophosphamide 6 Biopsy 6 pembrolizumab 5 Magnetic Resonance Spectroscopy 5 Leucovorin 5 Fluorouracil 5 Carboplatin 5 130-nm albumin-bound paclitaxel 5 venetoclax 4 toripalimab 4 lenvatinib 4 fludarabine 4 Specimen Handling 4 Radiotherapy 4 HMPL-013 4 Etoposide 4 Dexamethasone 4 Cisplatin 4 trametinib 3 sintilimab 3 enzalutamide 3

Date Range

30 days 90 days 1 year All

Options

Has results Has announcements

NCT06735820 2025-07-03

MEKMDM2

Children's National Research Institute

Phase 1/2 Not yet recruiting

Neurofibromatosis 1, Neurofibrosarcoma

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