NCT01772472 2025-07-22A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)Hoffmann-La RochePhase 3 Completed1,486 enrolled 37 charts 1 FDA
NCT01120184 2024-03-04A Study of Trastuzumab Emtansine (T-DM1) Plus Pertuzumab/Pertuzumab Placebo Versus Trastuzumab [Herceptin] Plus a Taxane in Participants With Metastatic Breast Cancer (MARIANNE)Hoffmann-La RochePhase 3 Completed1,095 enrolled 46 charts
NCT03084939 2023-05-06Efficacy and Safety of Trastuzumab Emtansine in Chinese Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Locally Advanced or Metastatic Breast CancerHoffmann-La RochePhase 3 Completed351 enrolled
NCT01702571 2022-04-04A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer Who Have Received Prior Anti-HER2 And Chemotherapy-based TreatmentHoffmann-La RochePhase 3 Completed2,185 enrolled 20 charts