Clinical Trials

23 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00318890 2019-02-05

Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Head and Neck

48 enrolled

Head and Neck Neoplasms

NCT03702985 2019-01-23

Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer

160 enrolled

CNSGastrointestinalGenitourinaryGynecologicOther solid neoplasmSarcoma

Locally Advanced Rectal Cancer

NCT00003926 2017-11-29

Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors

Phase 1 Terminated

13 enrolled

Ovarian Germ Cell Cancer, Astrocytoma, Brain Neoplasms, Chordoma, Ependymoma, Glioma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Hepatoblastoma, Desmoplastic Small Round Cell Tumor

NCT00503776 2017-06-20

Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia

Phase 2 Terminated

41 enrolled 12 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Deglutition Disorders, Head and Neck Neoplasms, Radiation Injuries, Salivary Gland Neoplasms, Xerostomia, Mucositis

NCT00270790 2017-02-01

EVALUATION OF AMIFOSTINE FOR MUCOSAL AND HEMOPOETIC PROTECTION AND CARBOPLATIN, TAXOL, RADIOTHERAPY IN THE MANAGEMENT OF PATIENTS WITH HEAD AND NECK CANCER.(GCC 0202)

21 enrolled 6 charts

Head and Neck Neoplasms

NCT00571298 2017-01-23

Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

Other solid neoplasmThoracic

141 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT00003657 2017-01-20

High-dose ICE With Amifostine

CNSGenitourinaryGynecologicHead & NeckSarcomaThoracic

24 enrolled

AIDS-related Kaposi sarcoma, Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Chondrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Ovarian Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT00095927 2017-01-04

Randomized Amifostine For SCCHN

58 enrolled

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Xerostomia, Mucositis

NCT00003582 2016-12-15

Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer

36 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Unknown Primary

NCT00006012 2016-07-06

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

73 enrolled

Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00217438 2015-08-21

Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple Myeloma

130 enrolled 6 charts

Plasma cell

Multiple Myeloma

NCT00012012 2015-01-07

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

45 enrolled 7 charts

Uterine Cervical Neoplasms, Radiation Injuries

NCT00003313 2014-11-21

Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer

243 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00098683 2014-02-13

Amifostine in Treating Young Patients With Newly Diagnosed De Novo Myelodysplastic Syndromes

Classical hematologyMyeloid

10 enrolled

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Myeloproliferative Disorders, Myelodysplastic-Myeloproliferative Diseases

NCT00003251 2013-12-04

Amifostine Plus Chemotherapy and Radiation Therapy in Treating Patients With Advanced, Unresectable Head and Neck Cancer

Phase 1/2 Unknown

46 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Radiation Injuries, Salivary Gland Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00003583 2013-12-04

Amifostine to Prevent Side Effects in Patients Who Are Receiving Chemotherapy and Radiation Therapy for Limited-Stage Small Cell Lung Cancer

20 enrolled

Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00003827 2013-12-04

Combination Chemotherapy in Treating Patients With Myelodysplastic Syndrome

Classical hematologyMyeloidOther hematologic neoplasm

25 enrolled

Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes

NCT00004264 2013-12-04

Docetaxel, Cisplatin, and Amifostine in Treating Patients With Advanced Non-small Cell Lung Cancer

Phase 1/2 Unknown

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00006105 2013-09-05

Gemcitabine, Cisplatin, and Amifostine Following Surgery in Treating Patients With Locally Advanced Bladder Cancer

37 enrolled

Genitourinary

Urinary Bladder Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT01586117 2013-08-15

A Phase II Study of Amifostine for the Prevention of Acute Radiation-Induced Rectal Toxicity

40 enrolled

Rectal Neoplasms

NCT00003268 2013-08-02

Amifostine and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Other hematologic neoplasm

Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute, Drug-Related Side Effects and Adverse Reactions

NCT00003089 2013-07-10

Chemotherapy, Amifostine, and Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00058071 2013-07-09

Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer

100 enrolled

Hydatidiform Mole, Peripheral Nervous System Diseases, Neurotoxicity Syndromes, Gestational Trophoblastic Disease

NCT00004919 2013-07-02

Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

30 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00003555 2013-06-26

Paclitaxel Plus Chemoprotection With Amifostine in Treating Patients With Recurrent or Refractory Solid Tumors

20 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003994 2013-06-14

Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver Cancer

277 enrolled

Hepatoblastoma

NCT00004176 2013-05-16

Amifostine, Chemotherapy, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

34 enrolled

Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00217542 2013-05-03

Azacitidine and Recombinant Interferon Alfa-2b in Treating Patients With Stage III or Stage IV Melanoma or Stage IV Kidney Cancer That Cannot Be Removed By Surgery

DermatologicGenitourinary

42 enrolled

Carcinoma, Renal Cell, Melanoma

NCT00003425 2013-04-26

Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotect

BreastCNSGynecologicLymphoidOther hematologic neoplasmPlasma cellSarcoma

25 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Neuroectodermal Tumors, Primitive, Peripheral, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00003624 2013-04-11

Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer

Phase 2 Terminated

GynecologicSarcoma

Carcinoma, Ovarian Epithelial, Uterine Cervical Neoplasms, Fallopian Tube Neoplasms, Ovarian Neoplasms, Sarcoma, Endometrial Neoplasms, Neurotoxicity Syndromes

NCT00003252 2013-03-26

Amifostine in Treating Patients With Cancer Who Have Neurological Changes Caused by Chemotherapy

Phase 4 Completed

Drug-Related Side Effects and Adverse Reactions

NCT00003136 2013-02-11

Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Epithelial Ovarian Cancer or Primary Peritoneal Cancer

11 enrolled

Carcinoma, Ovarian Epithelial, Ovarian Neoplasms

NCT00002643 2013-02-01

Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

130 enrolled

Sarcoma

Neutropenia, Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00003415 2013-01-31

Amifostine Plus Topotecan in Treating Patients With Myelodysplastic Syndrome

Classical hematologyMyeloidOther hematologic neoplasm

26 enrolled

Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00137358 2013-01-24

Radiation With Chemotherapy and a Study Drug to the Para-Aortic Nodes in Cervical Cancer

Phase 1 Withdrawn

Uterine Cervical Neoplasms, Neoplasms

NCT00003211 2012-11-07

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor

94 enrolled

CNS

Central Nervous System Neoplasms

NCT00078845 2012-10-17

Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors

BreastGenitourinaryGynecologicThoracic

24 enrolled

Carcinoma, Ovarian Epithelial, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Neurotoxicity Syndromes, Small Cell Lung Carcinoma

NCT00003143 2012-10-04

Combination Chemotherapy With or Without Amifostine in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Disease Undergoing Stem Cell Transplantation

LymphoidOther hematologic neoplasm

20 enrolled

Burkitt Lymphoma, Hodgkin Disease, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00025298 2012-09-24

Chemotherapy Plus Radiation Therapy With or Without Amifostine in Treating Patients With Locally Advanced Cancer of the Nasopharynx

Phase 2 Terminated

5 enrolled