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NCT06665724 2026-02-27

Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)

Phase 1 Completed

Astrocytoma, Glioblastoma, Oligodendroglioma

NCT05923060 2026-02-20

Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses

Phase 2 Completed

Keratosis, Actinic

NCT07053852 2026-01-02

Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage

Phase 1 Completed

Keratosis, Actinic

NCT04738162 2025-12-10

Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Brain Tumors

Phase 2 Completed

Brain Neoplasms

NCT06027619 2025-10-23

Short Contact Protocols to Reduce Pain During 10% ALA Gel Red-light Photodynamic Therapy of Actinic Keratoses

Phase 2 Completed

30 enrolled 13 charts

Keratosis, Actinic

NCT06159842 2025-02-12

Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (isSCC)

Phase 2 Completed

DermatologicGynecologic

Squamous Intraepithelial Lesions, Carcinoma, Squamous Cell, Skin Neoplasms

NCT03327831 2024-06-27

Study of Daylight Photodynamic Therapy With Aminolevulinic Acid for Actinic Keratoses

Phase 4 Completed

30 enrolled 7 charts

Keratosis, Actinic

NCT01128218 2023-11-30

A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors

Phase 1/2 Completed

33 enrolled 15 charts

Brain Neoplasms, Glioblastoma, Glioma

NCT01502280 2023-11-24

BALANCE

Phase 3 Completed

Glioma

NCT03109353 2023-01-13

Modification of Extracorporeal Photopheresis in Cutaneous T-cell Lymphoma or Chronic Graft-versus-host Disease

Phase 1/2 Completed

DermatologicLymphoid

Lymphoma, T-Cell, Cutaneous

NCT03281811 2023-01-05

Photodynamic Therapy in Treating Patients With Refractory Mycosis Fungoides

Phase EARLY_PHASE1 Completed

Mycosis Fungoides

NCT04055688 2022-05-31

Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas

Brain Neoplasms, Glioma

NCT03322293 2022-03-09

Daylight Photodynamic Therapy for Actinic Keratosis

Phase 1 Completed

24 enrolled 15 charts

Keratosis, Actinic

NCT02751151 2021-10-06

PDT

Phase NA Completed

Nonmelanoma Skin Cancers

NCT00752323 2021-09-17

Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01682811 2021-06-18

Phase I Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)

Phase 1 Completed

20 enrolled 11 charts

Neurofibromatoses

NCT01556009 2020-11-02

Vismodegib

Phase 2 Completed

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell

NCT02157623 2020-07-30

Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome

Phase NA Completed

3 enrolled 7 charts

Basal Cell Nevus Syndrome

NCT00870779 2019-06-14

FGR

Phase 1 Completed

Brain Neoplasms, Glioma, Meningioma, Pituitary Neoplasms, Skull Base Neoplasms

NCT00978081 2019-04-23

Photodynamic Therapy in Treating Patients With Premalignant or Early Stage Head and Neck Tumors

Phase 1 Completed

Head & NeckOther neoplasm

Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Precancerous Conditions

NCT00961090 2019-04-12

Safety Study of Aminolevulinic Acid (ALA) to Improve Visibility of Brain Tumors During Surgery

Phase 2 Completed

Brain Neoplasms, Glioblastoma, Glioma

NCT02685592 2018-05-30

LM PDT

Phase 4 Completed

Hutchinson's Melanotic Freckle

NCT01310868 2017-10-05

Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastoma

Phase 2 Completed

59 enrolled 8 charts

Glioblastoma, Gliosarcoma

NCT02622594 2017-07-19

Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy With Aminolevulinic Acid and Blue Light Versus Photodynamic Therapy With Aminolevulinic Acid and Blue Light Using Two Incubation Times

Phase 4 Completed

Keratosis, Actinic

NCT01812837 2017-06-15

The Use of Microneedles in Photodynamic Therapy

Phase NA Completed

51 enrolled 7 charts

Keratosis, Actinic

NCT02101931 2016-03-31

ALA

Phase 3 Completed

Urinary Bladder Neoplasms

NCT00571974 2015-03-24

Treatment of Oral Premalignant Lesions With 5-ALA PDT

Phase 1/2 Completed

29 enrolled 6 charts

Erythroplasia, Leukoplakia

NCT00002975 2013-10-10

Photodynamic Therapy in Treating Patients With Skin Cancer

Phase 2 Completed

180 enrolled 3 charts

DermatologicOther neoplasm

Carcinoma, Basal Cell, Precancerous Conditions, Keratosis, Actinic

NCT00002963 2013-01-31

Photodynamic Therapy in Treating Patients With Skin Cancer

Phase 2 Completed

Carcinoma, Basal Cell

NCT00054171 2013-01-31

Photodynamic Therapy in Treating Patients With Lymphoma or Chronic Lymphocytic Leukemia

Phase 2 Completed

DermatologicLymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, T-Cell, Cutaneous

NCT00671710 2011-01-14

Study of Aminolevulinic Acid to Enhance Visualization and Resection of Malignant Glial Tumors of the Brain

Phase 1 Completed

Brain Neoplasms