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Phase 2 2 Phase NA 1 Phase 3 1 Phase 1/2 1 Phase 1 1

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Completed 7 Terminated 3 Recruiting 3 Not yet recruiting 1 Active not recruiting 1

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Interventional 1

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Interventions

pembrolizumab 83 Cyclophosphamide 74 Nivolumab 53 fludarabine 46 Specimen Handling 39 Carboplatin 37 Magnetic Resonance Spectroscopy 36 Biopsy 32 fludarabine phosphate 29 Radiotherapy 26 Paclitaxel 26 Gemcitabine 25 Cisplatin 25 atezolizumab 24 venetoclax 22 Radiosurgery 21 Radiation 19 Ipilimumab 19 Dexamethasone 19 durvalumab 18 Bevacizumab 18 Rituximab 17 Lenalidomide 17 Temozolomide 16 Decitabine 16 Pemetrexed 15 Injections 15 Oxaliplatin 14 Fluorouracil 14 Docetaxel 14

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30 days 90 days 1 year All

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NCT04900792 2025-12-03

XACT-Fe-GBM-01

University of Iowa

Phase 1 Active not recruiting

Glioblastoma

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