NCT02336048 2021-04-08A Study Evaluating the Safety of Tocilizumab in Addition to Standard of Care Premedication Given Before Obinutuzumab + Chlorambucil in Participants With Untreated B-Cell Chronic Lymphocytic Leukemia (B-CLL) and ComorbiditiesHoffmann-La RochePhase 1 Terminated38 enrolled
NCT01283386 2019-03-14A Study to Compare Mabthera (Rituximab), Fludarabine and Cyclophosphamide to Mabthera and Chlorambucil in Participants With Chronic Lymphocytic Leukemia and Unfavorable Somatic StatusHoffmann-La RochePhase 4 Terminated26 enrolled 13 charts
NCT01980875 2018-11-19Efficacy and Safety of Idelalisib in Combination With Obinutuzumab Compared to Chlorambucil in Combination With Obinutuzumab for Previously Untreated Chronic Lymphocytic LeukemiaGilead SciencesPhase 3 Terminated57 enrolled 12 charts
NCT00151736 2012-06-11Safety and Efficacy of SDX-101 (R-Etodolac) in Combination With Chlorambucil, and That of Chlorambucil Alone, in Patients With Chronic Lymphocytic Leukemia (CLL)Teva Branded Pharmaceutical Products R&D, Inc.Phase 2 Terminated88 enrolled