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NETWORK × Interventional × Dactinomycin × Clear all

NCT07466316 2026-03-12

A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

Phase 3 Not yet recruiting

342 enrolled

Sarcoma

Rhabdomyosarcoma

NCT05304585 2026-02-24

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Phase 3 Recruiting

205 enrolled

Sarcoma

Rhabdomyosarcoma, Embryonal

NCT06647953 2026-02-24

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Phase 3 Recruiting

110 enrolled

Pleuropulmonary blastoma

NCT00945009 2025-05-31

Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor

Phase 3 Active not recruiting

249 enrolled 14 charts

Genitourinary

Beckwith-Wiedemann Syndrome, Wilms Tumor

NCT00354835 2023-01-31

Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Phase 3 Completed

481 enrolled 21 charts

Sarcoma

Rhabdomyosarcoma, Sarcoma

NCT02063022 2022-09-19

EW-1

Phase 3 Completed

278 enrolled

Sarcoma

Sarcoma, Ewing

NCT00075582 2021-11-19

Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Low-Risk Rhabdomyosarcoma

Phase 3 Completed

390 enrolled 14 charts

Sarcoma

Rhabdomyosarcoma

NCT00354744 2020-01-29

High-Dose Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Metastatic Rhabdomyosarcoma or Ectomesenchymoma

Phase 3 Completed

109 enrolled 12 charts

Sarcoma

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00003702 2018-05-15

Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia

Phase 3 Completed

240 enrolled 9 charts

Hydatidiform Mole

NCT00335556 2017-07-21

Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors

Phase 2 Completed

291 enrolled 18 charts

Genitourinary

Carcinoma, Renal Cell, Wilms Tumor

NCT00072280 2014-09-30

Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood Fibrosarcoma

Phase 2 Terminated

7 enrolled 9 charts

Sarcoma

Fibrosarcoma, Sarcoma

NCT00002610 2014-07-25

Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors

Phase 3 Completed

203 enrolled

Genitourinary

Kidney Neoplasms, Wilms Tumor

NCT00002995 2014-02-14

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Phase 3 Completed

483 enrolled

Sarcoma

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00003955 2014-02-14

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma

Phase 2 Completed

77 enrolled

Sarcoma

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00003958 2013-06-17

Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma

Phase 3 Completed

702 enrolled

Sarcoma

Malignant mesenchymal tumor, Rhabdomyosarcoma, Sarcoma

NCT00003688 2013-06-10

Dactinomycin in Treating Patients With Persistent or Recurrent Gestational Trophoblastic Neoplasia

Phase 2 Completed

Gynecologic

Gestational Trophoblastic Disease