Clinical Trials Browser

Phase 2 × Completed × Denosumab × Clear all

NCT02833610 2026-02-18

A Study of Denosumab in Multiple Myeloma Patients With Renal Insufficiency

Phase 2 Completed

Multiple Myeloma

NCT03839459 2026-01-28

Denosumab for Smoldering Multiple Myeloma

Phase 2 Completed

20 enrolled 8 charts

Smoldering Multiple Myeloma

NCT04907539 2025-04-16

A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC)

Phase 2 Completed

25 enrolled 22 charts

Gastrointestinal

Colorectal Neoplasms

NCT03792763 2025-02-11

DEFENCE

Phase 2 Completed

Smoldering Multiple Myeloma, Multiple Myeloma

NCT03620019 2024-08-12

Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma

Phase 2 Completed

25 enrolled 16 charts

Melanoma

NCT02470091 2024-01-22

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

Phase 2 Completed

56 enrolled 18 charts

Osteosarcoma

NCT03520231 2021-11-23

Study Comparing Denosumab With Standard Treatment in Urothelial Cancer Patients With Bone Metastases

Phase 2 Completed

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Kidney Neoplasms, Ureteral Neoplasms

NCT01951586 2021-10-25

Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer

Phase 2 Completed

226 enrolled 24 charts

Carcinoma, Non-Small-Cell Lung

NCT02366130 2021-10-07

Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer

Phase 2 Completed

45 enrolled 7 charts

Breast Neoplasms

NCT02682693 2021-02-02

GeparX

Phase 2 Completed

Carcinoma, Ductal, Breast, Inflammatory Breast Neoplasms

NCT00896454 2018-10-17

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

Phase 2 Completed

33 enrolled 22 charts

BreastGastrointestinalGenitourinaryHead & NeckLymphoidPlasma cellThoracic

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Hypercalcemia, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Parathyroid Neoplasms, Thyroid Neoplasms

NCT00091832 2014-01-28

Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer

Phase 2 Completed

255 enrolled 34 charts

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00104650 2011-01-24

Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates

Phase 2 Completed

111 enrolled 20 charts

Multiple Myeloma