Clinical Trials

Extensive Stage Small Cell Lung Cancer

NCT07155174 2026-03-17

SEZanne

180 enrolled

Phase 3 Not yet recruiting

Small Cell Lung Carcinoma

NCT07472517 2026-03-16

DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy

670 enrolled

Phase 1/2 Not yet recruiting

Small Cell Lung Carcinoma

NCT07472647 2026-03-16

SYS6090 Combination Therapy in Advanced Lung Cancer

596 enrolled

Carcinoma, Non-Small-Cell Lung, Small Cell Lung Carcinoma

NCT03591510 2026-03-13

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

22 enrolled

Leukemia, Myeloid, Acute

NCT06449209 2026-03-12

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

110 enrolled

Small Cell Lung Carcinoma

NCT05091567 2026-03-10

IMforte

660 enrolled 23 charts 1 FDA

Small Cell Lung Carcinoma

NCT05533775 2026-03-06

iMATRIX GLO

65 enrolled

Recurrence

NCT06646276 2026-03-04

A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

530 enrolled

Small Cell Lung Carcinoma

NCT05361395 2026-03-03

First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC)

184 enrolled

Bites and Stings, Lung Neoplasms

NCT05815160 2026-02-27

Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

34 enrolled

Recurrence, Small Cell Lung Carcinoma

NCT07005128 2026-02-27

DeLLphi-312

330 enrolled

Small Cell Lung Carcinoma

NCT07227597 2026-02-20

MK-6070-003

170 enrolled

Small Cell Lung Cancer Extensive Stage

NCT03407144 2026-02-19

MK-3475-667

340 enrolled

Lymphoid

Hodgkin Disease

NCT02861573 2026-02-17

KEYNOTE-365

1,200 enrolled

Genitourinary

Metastatic Castration-Resistant Prostate Cancer

NCT04665856 2026-02-13

SKYSCRAPER-02C

123 enrolled 26 charts

Small Cell Lung Carcinoma

NCT06712355 2026-02-13

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

621 enrolled

Lung Neoplasms, Small Cell Lung Carcinoma

NCT03182244 2026-02-06

A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation

276 enrolled 41 charts

Leukemia, Myeloid, Acute

NCT06230224 2026-02-06

OLYMPIA-4

Phase 1/2 Active not recruiting

216 enrolled

Lymphoid

Lymphoma, Non-Hodgkin, Lymphoma, B-Cell

NCT06771622 2026-02-04

Safety and Efficacy of HCB101 in Combination With Multiple Agents in Patients With Advanced Solid Tumors

500 enrolled

Solid Cancer

NCT04256421 2026-01-28

SKYSCRAPER-02

490 enrolled 31 charts

Small Cell Lung Carcinoma

NCT06564844 2026-01-27

TROPION-Lung12

24 enrolled

Adenocarcinoma, Carcinoma, Non-Small-Cell Lung

NCT03926624 2026-01-22

Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage

Phase 3 Terminated

167 enrolled

Phase 2/3 Active not recruiting

Leukemia, Myeloid, Acute

NCT06105619 2026-01-20

A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).

84 enrolled

CNS

Glioblastoma

NCT07268040 2026-01-12

A Trial of SHR-7787 Injection Combined With Other Anti-tumor Drugs in Patients With Malignant Solid Tumors

400 enrolled

Malignant Solid Tumors

NCT06741644 2026-01-09

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

660 enrolled

Advanced Solid Tumors

NCT06077500 2026-01-06

DAREONᵀᴹ-8

45 enrolled

Small Cell Lung Carcinoma

NCT06132113 2025-12-17

DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers

Phase 1 Recruiting

55 enrolled

Endocrine

Neuroendocrine Neoplasms

NCT04063163 2025-12-09

A Phase III Study to Investigate Efficacy and Safety of HLX10 + Chemotherapy in Patients With ES-SCLC

585 enrolled 14 charts

Small Cell Lung Carcinoma

NCT02421939 2025-12-04

A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation

371 enrolled 36 charts 2 FDA

Leukemia, Myeloid, Acute

NCT07245446 2025-11-24

A Study of Ivonescimab in First-Line ES-SCLC

180 enrolled

Small Cell Lung Carcinoma

NCT03043872 2025-10-21

CASPIAN

987 enrolled 42 charts 2 FDA

Small Cell Lung Carcinoma

NCT02964013 2025-10-14

KEYVIBE-001

Phase 1 Completed

474 enrolled 39 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Neoplasms

NCT04702880 2025-10-08

A Study of BMS-986012 in Combination With Carboplatin, Etoposide, and Nivolumab as First-line Therapy in Extensive-stage Small Cell Lung Cancer

120 enrolled

Small Cell Lung Carcinoma

NCT03041311 2025-09-25

Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLC

Phase 2 Completed

107 enrolled 42 charts

LymphoidOther hematologic neoplasm

Small Cell Lung Carcinoma

NCT03860844 2025-09-09

ISAKIDS

Phase 2 Terminated

67 enrolled 25 charts

Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04047862 2025-08-22

Study of Ociperlimab (BGB-A1217) in Combination With Tislelizumab in Advanced Solid Tumors

Phase 1 Completed

446 enrolled 49 charts

Locally Advanced and Metastatic Solid Tumors

NCT05595460 2025-08-12

Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC

Phase 1 Recruiting

49 enrolled

SCLC,Extensive Stage

NCT05298423 2025-08-01

KEYVIBE-006

611 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT04924101 2025-07-23

KEYNOTE-B99

Phase 2 Completed

126 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Small Cell Lung Carcinoma

NCT07009457 2025-07-04

Phase I Clinical Study of SHR-1316 (SC) Combined With Carboplatin and Etoposide as First-line Treatment for Extensive Stage Small Cell Lung Cancer

Phase 1 Recruiting

48 enrolled

Widespread Small Cell Lung Cancer

NCT04624204 2025-07-02

MK 7339-013

672 enrolled

Parkinson Disease 4, Autosomal Dominant Lewy Body, Small Cell Lung Carcinoma

NCT06719973 2025-06-17

Phase 1 Study of M9466 Combined With Carboplatin and Platinum-based Anticancer Therapy (DDRiver 521)

Phase 1 Withdrawn

Advanced Solid Tumors

NCT04774380 2025-05-23

LUMINANCE

152 enrolled 17 charts

Small Cell Lung Carcinoma

NCT06030258 2025-04-30

IN10018 Combination Therapy in Treatment-naïve ES-SCLC

120 enrolled

Small Cell Lung Cancer Extensive Stage

NCT02632708 2025-04-11

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

153 enrolled

Leukemia, Myeloid, Acute

NCT06897579 2025-04-11

Carboplatin/Cisplatin + Etoposide + Benmelstobart Sequential Benmelstobart Combined With Anlotinib Versus Carboplatin/Cisplatin + Etoposide + Tislelizumab Sequential Tislelizumab in the Treatment of Extensive Stage Small Cell Lung Cancer

134 enrolled

Extensive Stage Small Cell Lung Cancer

NCT04778410 2025-03-20

Study of Magrolimab Combinations in Participants With Myeloid Malignancies

Phase 2 Terminated

54 enrolled 26 charts

Myeloid Malignancies

NCT04101357 2025-03-18

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411

Phase 1/2 Terminated

54 enrolled 30 charts