Clinical Trials

15 enrolled 18 charts

Breast Neoplasms

NCT02813135 2026-01-16

ESMART

Phase 1/2 Recruiting

472 enrolled

Tumor-Agnostic

Neoplasms

NCT00081874 2025-04-27

RAD001 in Relapsed or Refractory AML, ALL, CML in Blastic-Phase, Agnogenic Myeloid Metaplasia, CLL, T-Cell Leukemia, or Mantle Cell Lymphoma

LymphoidMyeloidOther hematologic neoplasm

29 enrolled

Leukemia, Recurrence, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, T-Cell, Leukemia, Myeloid, Acute, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Primary Myelofibrosis

NCT04339062 2025-04-23

CONTRAC

12 enrolled 13 charts

Dermatologic

Cutaneous Squamous Cell Carcinoma

NCT02991807 2025-02-17

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

46 enrolled 15 charts

Autistic Disorder, Hamartoma Syndrome, Multiple, Intellectual Disability

NCT00934895 2023-09-18

Phase I/II Study of Weekly Abraxane and RAD001 in Women With Locally Adv. or Metastatic Breast Ca

27 enrolled 12 charts

Breast Neoplasms

NCT02871791 2022-08-29

Palbociclib With Everolimus + Exemestane In BC

41 enrolled 12 charts

Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

NCT02205515 2022-08-19

EBRT

17 enrolled

Endocrine

Carcinoma, Neuroendocrine

NCT01582009 2022-08-15

Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate

26 enrolled 11 charts

Carcinoma, Renal Cell

NCT03805399 2022-08-10

FUTURE

Phase 1/2 Unknown

140 enrolled

Triple Negative Breast Neoplasms

NCT01034631 2022-07-11

BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma

154 enrolled 22 charts

Carcinoma, Renal Cell, Kidney Neoplasms

NCT00392821 2022-06-06

Dosing and Effectiveness Study of Sorafenib and RAD001 in the Treatment of Patients With Advanced Kidney Cancer

78 enrolled 11 charts

Kidney Neoplasms

NCT01784861 2021-07-08

VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Everolimus for Treating Patients With Pancreatic Neuroendocrine Tumors

23 enrolled 17 charts

Adenocarcinoma, Pancreatic Neoplasms

NCT01125293 2021-04-23

Everolimus, Bortezomib and/or Rituximab in Patients With Relapsed/Refractory Waldenstrom's Macroglobulinemia

46 enrolled 29 charts

Lymphoid

Waldenstrom Macroglobulinemia

NCT01077986 2021-04-21

Everolimus, Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancer

35 enrolled

Pancreatic Neoplasms

NCT01075321 2020-10-22

Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

LymphoidOther hematologic neoplasm

58 enrolled 12 charts

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Follicular, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell

NCT02061397 2020-08-25

SOS

10 enrolled 6 charts

Tuberous Sclerosis, Lymphangioleiomyomatosis

NCT00576680 2020-07-09

RAD001 and Temozolomide in Patients With Advanced Pancreatic Neuroendocrine Tumors

43 enrolled 8 charts

Adenoma, Islet Cell

NCT00918333 2020-03-10

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

DermatologicLymphoidOther hematologic neoplasmPlasma cell

124 enrolled 10 charts

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Follicular, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell

NCT00553150 2020-02-13

Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

122 enrolled 11 charts

CNSSarcoma

Astrocytoma, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01783756 2019-11-12

Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis

9 enrolled

Breast Neoplasms, Breast Neoplasms, Male

NCT01453504 2019-11-08

HD-R3i

73 enrolled

Lymphoid

Hodgkin Disease

NCT00474929 2019-08-20

Sorafenib and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

DermatologicLymphoidOther hematologic neoplasmPlasma cell

103 enrolled 12 charts

Burkitt Lymphoma, Hodgkin Disease, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell

NCT01514110 2019-04-02

Gastric Cancer RAD001 Study

35 enrolled

Stomach Neoplasms

NCT00968253 2019-02-27

RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemia

LymphoidOther hematologic neoplasm

24 enrolled 9 charts

Leukemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01031446 2018-08-31

Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer

55 enrolled 12 charts

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT03629847 2018-08-14

Treatment of Neuroendocrine Tumors (NETs) With Combination of Everolimus and Radiolabeled Somatostatin Analogue

Phase 1/2 Unknown

30 enrolled

EndocrineNET

Metatropic dwarfism, Neuroendocrine Tumors

NCT01009346 2018-07-17

RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic SCCHN

9 enrolled 9 charts

Head & Neck

Head and Neck Neoplasms

NCT01259063 2018-03-13

RAD001 and Intravesical Gemcitabine in BCG-Refractory Primary or Secondary Carcinoma In Situ of the Bladder

33 enrolled 11 charts

Urinary Bladder Neoplasms

NCT01139138 2017-11-06

PIE

49 enrolled

Colorectal Neoplasms

NCT00935792 2017-09-26

Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Other hematologic neoplasm

28 enrolled 13 charts

Leukemia, Lymphoid, Hematologic Neoplasms

NCT01462214 2017-05-10

Study of Everolimus and Low-dose Cyclophosphamide in Patients With Metastatic Renal Cell Cancer

96 enrolled

Carcinoma, Renal Cell

NCT01058655 2017-04-13

RAD001 and AV-951 in Patients With Refractory, Metastatic Colorectal Cancer

56 enrolled 15 charts

Gastrointestinal Neoplasms, Colorectal Neoplasms

NCT00574769 2017-04-11

Safety Study & Effectiveness of Docetaxel With RAD001 and Bevacizumab in Men With Advanced Prostate Cancer

27 enrolled

Neoplasm Metastasis, Prostatic Neoplasms

NCT01047293 2017-04-04

RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma

47 enrolled 6 charts

Colorectal Neoplasms

NCT01070316 2017-03-13

Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)

20 enrolled 8 charts

Epilepsy, Hereditary Sensory and Autonomic Neuropathies, Tuberous Sclerosis

NCT00516165 2017-02-07

RAD001 in Advanced Hepatocellular Carcinoma

28 enrolled 11 charts

Carcinoma, Hepatocellular, Liver Neoplasms

NCT00458237 2016-10-20

Dose Escalation Followed by Study of RAD001 in Combination With Trastuzumab in HER2-Positive Metastatic Breast Cancer

11 enrolled 8 charts

Breast Neoplasms

NCT00459186 2016-05-16

The Use of RAD001 With Docetaxel in the Treatment of Metastatic, Androgen Independent Prostate Cancer

19 enrolled 6 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT00448149 2016-03-17

Phase I/II Trial of RAD001 Plus Nexavar in Patients With Kidney Cancer

55 enrolled

Carcinoma, Renal Cell, Kidney Neoplasms

NCT01333085 2016-02-10

CAPRA

49 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Tongue Neoplasms

NCT00085566 2016-01-20

Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer

61 enrolled 8 charts

CNSGenitourinarySarcoma

Brain Neoplasms, Glioblastoma, Prostatic Neoplasms, Central Nervous System Neoplasms, Gliosarcoma

NCT01099527 2015-12-29

A Trial of RAD001/Capecitabine in Refractory Gastric Cancer

59 enrolled

Neoplasm Metastasis, Stomach Neoplasms

NCT01042028 2015-10-20

A Randomised Trial With Irinotecan, Cetuximab and Everolimus (ICE)Compared to Capecitabine and Oxaliplatin (CapOx) for Patients With Gemcitabin Resistant Pancreatic Cancer

39 enrolled

Pancreatic Neoplasms

NCT01009801 2015-07-07

Transarterial Chemoembolization With Doxorubicin With or Without Everolimus in Treating Patients With Liver Cancer

27 enrolled

Carcinoma, Hepatocellular, Liver Neoplasms

NCT00522665 2015-05-15

Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer

41 enrolled

MyeloidOther hematologic neoplasm

Colorectal Neoplasms

NCT01188889 2015-05-15

RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w/ Molecular Disease.

Phase 1/2 Withdrawn

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT01198665 2015-03-03

RADCHOP

46 enrolled

DermatologicLymphoid

Immunoblastic Lymphadenopathy, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic

NCT00967044 2015-02-26

Panobinostat (LBH589) Plus Everolimus (RAD001) in Patients With Relapsed and Refractory Lymphoma