Clinical Trials Browser

Completed × Interventional × Fluconazole × Clear all

NCT04551963 2024-10-26

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

Phase 1 Completed

26 enrolled 20 charts

B-cell Malignancies

NCT01503515 2024-10-16

Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant

Phase 3 Completed

292 enrolled 12 charts

Other hematologic neoplasm

Mycoses, Hematologic Neoplasms

NCT05602597 2024-03-06

HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI

Phase 1 Completed

Lymphoma, Recurrence

NCT03028103 2023-06-26

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Phase 1 Completed

32 enrolled 30 charts

Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT05661591 2023-04-04

Effect of Fluconazole on Pharmacokinetics of SHR2554 in Healthy Subjects

Phase 1 Completed

Neoplasms

NCT00075803 2023-01-04

BMT CTN 0101

Phase 3 Completed

600 enrolled 22 charts

LymphoidMyeloidOther hematologic neoplasm

Infections, Leukemia, Lymphoma, Myelodysplastic-Myeloproliferative Diseases

NCT02222922 2020-12-17

A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors

Phase 1 Completed

138 enrolled 98 charts

BreastGynecologicThoracic

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Triple Negative Breast Neoplasms

NCT03159845 2020-01-07

ZENITH

Phase 2 Completed

Stem Cell Transplant Complications

NCT04193319 2019-12-10

Effect of Fluconazole on PK of Fluzoparib in Healthy Male Subjects

Phase 1 Completed

Advanced Cancer

NCT02122770 2019-01-07

Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors

Phase 1 Completed

51 enrolled 30 charts

Other solid neoplasm

Advanced Solid Tumors

NCT00002533 2016-12-15

Fluconazole in Preventing Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Phase 2/3 Completed

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Infections, Esthesioneuroblastoma, Olfactory

NCT02093390 2016-06-06

A Phase 1 Study to Evaluate the Effects of Fluconazole and Atorvastatin on the Pharmacokinetics of TAK-385 in Healthy Subjects

Phase 1 Completed

40 enrolled 23 charts

Endometriosis, Prostatic Neoplasms

NCT00023530 2016-02-18

Blood and Marrow Transplant Clinical Research Network

Phase NA Completed

MyeloidOther hematologic neoplasmPlasma cell

Graft vs Host Disease, Hematologic Diseases, Leukemia, Multiple Myeloma, Myelodysplastic Syndromes

NCT02093728 2015-06-30

To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

Phase 1 Completed

Other solid neoplasm

Solid Tumours

NCT00003883 2010-04-02

Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation

Phase 3 Completed

BreastCNSDermatologicGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

Teratoma, Testicular, Carcinoma, Ovarian Epithelial, Blast Crisis, Breast Neoplasms, Burkitt Lymphoma, Hodgkin Disease, Infections, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Mycosis Fungoides, Neoplasms, Wilms Tumor, Neuroblastoma, Recurrence, Sezary Syndrome, Teratoma, Testicular Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Carcinoma, Embryonal, Seminoma, Endodermal Sinus Tumor, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis