AZD2014 and Fulvestrant in Patients With ER+ Advanced Metastatic Breast Cancer
Phase 1 Completed
99 enrolled 61 charts
B-PRECISE-01
Phase 1 Completed
62 enrolled 18 charts
This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer
Phase 1 Completed
133 enrolled 26 charts
T-VEC With Chemotherapy or Endocrine Therapy in Treating Participants With HER2- Negative Breast Cancer
Phase 1 Completed
20 enrolled
WI231696: Bosutinib, Palbocicilib and Fulvestrant for HR+HER2- Advanced Breast Cancer Refractory to a CDK4/6 Inhibitor
Phase 1 Completed
19 enrolled
Fulvestrant, Palbociclib and Erdafitinib in ER+/HER2-/FGFR-amplified Metastatic Breast Cancer
Phase 1 Completed
35 enrolled 19 charts
A Phase 1 Study of LY2835219 In Participants With Advanced Cancer
Phase 1 Completed
225 enrolled 31 charts
PASTOR
Phase 1 Completed
54 enrolled
Open Label, Sequential Dosing , Single Ascending Dose and Multiple Dose Safety Tolerability and Pharmacokinetic Study
Phase 1 Completed
48 enrolled
A Phase Ib Dose Escalation Study of the Combination of LEE011 With Letrozole and Dose Expansion of LEE011 With Hormonal Therapy for the Treatment of Pre-(With Goserelin) and Postmenopausal Women With Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer
Phase 1 Completed
88 enrolled
AZD5363 in Patients With Advanced Solid Tumors Harboring AKT Mutations
Phase 1 Completed
12 enrolled
A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With Palbociclib/Letrozole Or Palbociclib/Fulvestrant In Women With Metastatic Breast Cancer
Phase 1 Completed
141 enrolled
A Study of LY3023414 in Participants With Advanced Cancer
Phase 1 Completed
156 enrolled
Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alobresib (Formerly GS-5829) in Adults With Advanced Solid Tumors and Lymphomas and in Combination With Exemestane or Fulvestrant in Adults With Estrogen Receptor Positive Breast Cancer
Phase 1 Completed
33 enrolled 23 charts
Study of LEE011 With Fulvestrant and BYL719 or BKM120 in Advanced Breast Cancer
Phase 1 Completed
70 enrolled
A Study of BYL719 in Adult Patients With Advanced Solid Malignancies, Whose Tumors Have an Alteration of the PIK3CA Gene
Phase 1 Completed
221 enrolled
D6090C00002
Phase 1 Completed
49 enrolled
Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer
Phase 1 Completed
101 enrolled 33 charts
14C
Phase 1 Completed
4 enrolled 34 charts
MK2206 in Combination With Anastrozole, Fulvestrant, or Anastrozole and Fulvestrant in Treating Postmenopausal Women With Metastatic Breast Cancer
Phase 1 Completed
31 enrolled
BKM120 and Fulvestrant for Treating Postmenopausal Patients With Estrogen Receptor-Positive Stage IV Breast Cancer
Phase 1 Completed
31 enrolled
Phase I, Dose Study to Look at the Safety and Pharmacokinetics of AZD8835 in Patients With Advanced Solid Tumours
Phase 1 Completed
20 enrolled
Faslodex 500mg Multiple Dose Tolerability Study in BC Patients
Phase 1 Completed
20 enrolled