Clinical Trials Browser

Phase 1 × Interventional × Hydroxyurea × Clear all

Bites and Stings

NCT06871410 2026-01-26

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Phase 1 Recruiting

26 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT07190833 2025-09-24

A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients (South Korea)

Phase 1 Not yet recruiting

27 enrolled

Other solid neoplasm

Treatment-Refractory Solid Tumors

NCT06005324 2025-06-08

Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer

Phase 1 Recruiting

36 enrolled

HPV-Negative Squamous Cell Carcinoma

NCT01847326 2024-07-31

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer

Phase 1 Completed

48 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT03463733 2020-10-08

HUTMZ

Phase 1 Unknown

54 enrolled

CNS

Glioblastoma, Glioma

NCT00387933 2015-10-14

Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma

Phase 1 Completed

37 enrolled

CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00019058 2015-04-29

Radiation Therapy in Treating Patients With Glioblastoma

Phase 1 Completed

34 enrolled

CNSSarcoma

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT00002887 2013-09-17

Hydroxyurea Plus Combination Chemotherapy in Patients With Non-small Cell Lung Cancer

Phase 1 Unknown

30 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00613132 2013-02-20

Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG

Phase 1 Completed

78 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00023959 2013-02-07

Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

Phase 1 Completed

39 enrolled

CNSHead & Neck

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Esthesioneuroblastoma, Olfactory

NCT00613054 2012-12-05

Ph I Zactima + Imatinib Mesylate & Hydroxyurea for Pts w Recurrent Malignant Glioma

Phase 1 Completed

27 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT01521299 2012-08-28

A Dose Escalation Study of Hydroxyurea in Combination With SCH900776 in Advanced Malignant Solid Tumors

Phase 1 Withdrawn

Other solid neoplasm

Advanced Solid Tumors

Clinical Trials

OASIS

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients (South Korea)

Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer

HUTMZ

Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma

Radiation Therapy in Treating Patients With Glioblastoma

Hydroxyurea Plus Combination Chemotherapy in Patients With Non-small Cell Lung Cancer

Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG

Bevacizumab, Fluorouracil, and Hydroxyurea Plus Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer

Ph I Zactima + Imatinib Mesylate & Hydroxyurea for Pts w Recurrent Malignant Glioma

A Dose Escalation Study of Hydroxyurea in Combination With SCH900776 in Advanced Malignant Solid Tumors