Clinical Trials Browser

OTHER × Interventional × Hydroxyurea × Clear all

NCT06930352 2026-03-13

Ziftomenib for the Treatment of Patients With NPM1 Mutated or KMT2A Rearranged Acute Myeloid Leukemia Not Eligible for Standard Therapy

Phase 2 Not yet recruiting

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT06955169 2026-02-17

MOMENTUM-1

Phase 2 Recruiting

Meningioma

NCT06871410 2026-01-26

Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Phase 1 Recruiting

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT06199557 2025-06-29

HUVAMER

Phase 1/2 Recruiting

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT06005324 2025-06-08

Personalized, Adaptive Treatment for Locally Advanced Head and Neck Cancer

Phase 1 Recruiting

HPV-Negative Squamous Cell Carcinoma

NCT03944915 2025-05-11

DEPEND

Phase 2 Completed

35 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT03107182 2025-05-06

OPTIMA-II

Phase 2 Completed

72 enrolled 14 charts

Squamous Cell Carcinoma of Head and Neck

NCT04116502 2024-11-18

MITHRIDATE

Phase 3 Recruiting

Polycythemia Vera

NCT02258659 2024-09-24

OPTIMA

Phase 2 Completed

62 enrolled 13 charts

Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections

NCT05005182 2024-09-19

Luspatercept With or Without Hydroxyurea for the Treatment of Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis or Unclassifiable With Ring Sideroblasts

Phase 2 Terminated

3 enrolled 12 charts

Myeloproliferative Disorders, Thrombocytosis

NCT01847326 2024-07-31

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer

Phase 1 Completed

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT02626715 2024-07-16

Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS

Phase 2 Completed

21 enrolled 24 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01693718 2024-01-29

A Multicenter Study of Intensive Concomitant Chemoradiotherapy With Filgrastim (GCSF) for Patients With Locoregionally Advanced Head and Neck Cancer

Phase 2 Completed

Laryngeal Diseases, Neoplasms

NCT02899169 2021-09-08

APL16

Phase 3 Unknown

Other hematologic neoplasm

Leukemia, Promyelocytic, Acute

NCT00006119 2021-02-21

Hydroxyurea in Treating Patients With Recurrent and/or Unresectable Meningioma

Phase 2 Completed

Brain Neoplasms, Meningioma, Central Nervous System Neoplasms

NCT03463733 2020-10-08

HUTMZ

Phase 1 Unknown

Glioblastoma, Glioma

NCT00468169 2019-10-09

EPIC

Phase 2 Completed

110 enrolled 14 charts

Carcinoma, Head and Neck Neoplasms, Neoplasms

NCT01964755 2019-09-23

Chemotherapy for Relapsed Epstein Barr Virus Associated Lymphoma

Phase 2 Terminated

6 enrolled 14 charts

Hodgkin Disease, Lymphoma, Non-Hodgkin, Epstein-Barr Virus Infections

NCT00019474 2018-09-14

Combination Chemotherapy Plus Interferon Alfa Followed by Filgrastim in Treating Patients With Gastrointestinal Tract Cancer

Phase 2 Completed

Gastrointestinal

Bile Duct Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms

NCT00055874 2018-05-03

Imatinib Mesylate With or Without Interferon Alfa or Cytarabine Compared With Interferon Alfa Followed by Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

Phase 3 Completed

MyeloidOther hematologic neoplasm

Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT00462735 2018-03-13

Fluorouracil, Hydroxyurea, Cetuximab and Twice-daily Intensity Radiation Therapy for Advanced Head and Neck Cancer

Phase 2 Completed

33 enrolled 15 charts

Head and Neck Neoplasms, Laryngeal Neoplasms, Nose Neoplasms, Paranasal Sinus Neoplasms, Pharyngeal Neoplasms

NCT00978146 2017-04-20

Effect of Hydroxyurea as Treatment for Primary Desmoid Tumors

Phase 2 Withdrawn

Fibroma, Desmoid Tumors

NCT00706810 2017-04-13

Combination of Hydroxyurea and Verapamil for Refractory Meningiomas

Phase 2 Completed

8 enrolled 5 charts

Brain Neoplasms, Meningioma, Neoplasms

NCT00004933 2016-07-04

Homoharringtonine Compared With Hydroxyurea for Chronic Myelogenous Leukemia That Has Not Responded to Interferon Alfa

Phase 3 Terminated

MyeloidOther hematologic neoplasm

Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Chronic-Phase

NCT00387933 2015-10-14

Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma

Phase 1 Completed

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT02480608 2015-06-24

CML2004

Phase 1/2 Completed

MyeloidOther hematologic neoplasm

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT00002951 2013-09-05

Chemotherapy Plus Radiation Therapy in Treating Patients With Head and Neck Cancer

Phase 2 Completed

GastrointestinalHead & Neck

Esophageal Neoplasms, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms

NCT00615927 2013-03-15

Phase II Imatinib + Hydroxyurea in Treatment of Patients With Recurrent/Progressive Grade II Low-Grade Glioma (LGG)

Phase 2 Completed

64 enrolled 9 charts

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00613132 2013-02-20

Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG

Phase 1 Completed

Brain Neoplasms, Glioblastoma, Gliosarcoma

NCT00613054 2012-12-05

Ph I Zactima + Imatinib Mesylate & Hydroxyurea for Pts w Recurrent Malignant Glioma

Phase 1 Completed

Brain Neoplasms, Glioblastoma, Glioma, Gliosarcoma

NCT00002940 2012-10-19

Hydroxyurea in Treating Patients With Epstein-Barr Virus-Associated Primary CNS Lymphoma and AIDS

Phase 2 Completed

Lymphoma

NCT01521299 2012-08-28

A Dose Escalation Study of Hydroxyurea in Combination With SCH900776 in Advanced Malignant Solid Tumors

Phase 1 Withdrawn

Other solid neoplasm

Advanced Solid Tumors

NCT01645124 2012-07-20

CYTO-PV

Phase 3 Terminated

Polycythemia, Polycythemia Vera, Thrombosis

NCT00004897 2012-06-12

Combination Chemotherapy and Interferon Alfa Followed by Surgery and/or Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer

Phase 2 Terminated

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Esophageal Neoplasms