Clinical Trials Browser

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Head and Neck Neoplasms, Melanoma, Ovarian Neoplasms, Colorectal Neoplasms, Triple Negative Breast Neoplasms

NCT03792841 2025-10-16

Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC

Phase 1 Terminated

212 enrolled

Genitourinary

Bites and Stings, Prostatic Neoplasms

NCT04417465 2025-09-25

First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors

Phase 1 Completed

101 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Neoplasms

NCT06896422 2025-08-07

Randomized Trial of Glutathione With Anti-PD-1 and Chemotherapy in Advanced NSCLC

Phase 1 Recruiting

80 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT07034118 2025-06-24

Definitive Proton Radiotherapy Combined With Chemotherapy and Immunotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Phase I Clinical Study

Phase 1 Not yet recruiting

23 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT06063681 2025-06-08

A Study of SR-8541A (ENPPI Inhibitor) in Advanced/Metastatic Solid Tumors

Phase 1 Recruiting

25 enrolled

Neoplasm Metastasis, Recurrence

NCT05704985 2025-05-29

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

Phase 1 Active not recruiting

39 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms, Kidney Neoplasms, Neoplasms, Pancreatic Neoplasms, Skin Neoplasms, Colorectal Neoplasms

NCT06966583 2025-05-12

NMN

Phase 1 Not yet recruiting

20 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04625205 2025-04-06

A Clinical Study of the Safety and Activity of the Investigational Cell Therapy NEO-PTC-01 in Patients With Advanced Melanoma

Phase 1 Terminated

22 enrolled

Dermatologic

Melanoma

NCT06026254 2024-11-18

A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial

Phase 1 Active not recruiting

2 enrolled

Other solid neoplasm

Solid Tumor, Adult

NCT06431685 2024-05-28

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

Phase 1 Recruiting

10 enrolled

CNS

Meningeal Carcinomatosis

NCT05615142 2024-04-17

Safety and Tolerability of Low Dose Radiotherapy Concurrent SBRT and PD-1 Inhibitors in Advanced NSCLC.

Phase 1 Recruiting

9 enrolled

Thoracic

NSCLC

NCT05735028 2024-04-17

The Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Centipeda Minima (CM) in Lung Cancer

Phase 1 Recruiting

8 enrolled

Thoracic

Lung Neoplasms

NCT03790488 2023-07-03

Study of a PD-1 Inhibitor (JTX-4014) in Subjects With Solid Tumor Malignancies

Phase 1 Completed

18 enrolled

Tumor-Agnostic

Neoplasms

NCT04864379 2021-04-28

Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors

Phase 1 Unknown

30 enrolled

Other solid neoplasm

Advanced Malignant Solid Tumor

NCT03987867 2020-07-07

Study of Autologous CIK Cell Immunotherapy Combination With PD-1 Inhibitor and Chemotherapy in the Advanced NSCLC

Phase 1 Unknown

30 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT03991559 2019-08-28

A Safety Study of the Pan-immunotherapy in Patients With Unresectable/Metastatic Solid Tumors or Lymphomas

Phase 1 Unknown

20 enrolled

Lymphoid

Lymphoma, Neoplasm Metastasis

NCT02574533 2017-09-27

Pilot Study of Vigil™ + Pembrolizumab for Advanced Melanoma

Phase 1 Completed

2 enrolled

Dermatologic

Melanoma

Clinical Trials

CIML NK Cell in Head & Neck Cancer

iFOCUS

Exploratory Clinical Study of FAP mRNA Vaccine in Patients With Advanced Malignant Solid Tumors

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

Safety and Tolerability of LDRT Plus Concurrent Partial SBRT and Tislelizumab in Patients With Bulky Tumors

AT1019 Plus SBRT and PD-1 Inhibitor for Advanced Solid Tumors: An IIT Study

Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies

Safety, Tolerability, Pharmacokinetics, and Efficacy of Acapatamab in Subjects With mCRPC

First In Human Study With ABBV-CLS-579 When Given Alone and In Combination In Participants With Locally Advanced Or Metastatic Tumors

Randomized Trial of Glutathione With Anti-PD-1 and Chemotherapy in Advanced NSCLC

Definitive Proton Radiotherapy Combined With Chemotherapy and Immunotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Phase I Clinical Study

A Study of SR-8541A (ENPPI Inhibitor) in Advanced/Metastatic Solid Tumors

Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors

NMN

A Clinical Study of the Safety and Activity of the Investigational Cell Therapy NEO-PTC-01 in Patients With Advanced Melanoma

A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

Safety and Tolerability of Low Dose Radiotherapy Concurrent SBRT and PD-1 Inhibitors in Advanced NSCLC.

The Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Centipeda Minima (CM) in Lung Cancer

Study of a PD-1 Inhibitor (JTX-4014) in Subjects With Solid Tumor Malignancies

Clinical Study of a Personalized Neoantigen Cancer Vaccine Combined With Anti-PD-1 and RFA in Patients With Solid Tumors

Study of Autologous CIK Cell Immunotherapy Combination With PD-1 Inhibitor and Chemotherapy in the Advanced NSCLC

A Safety Study of the Pan-immunotherapy in Patients With Unresectable/Metastatic Solid Tumors or Lymphomas

Pilot Study of Vigil™ + Pembrolizumab for Advanced Melanoma