Clinical Trials

BreastCNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidOther hematologic neoplasmPlasma cellThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioblastoma, Carcinoma, Hepatocellular, Liver Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Melanoma, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Ovarian Neoplasms, Prostatic Neoplasms, Colorectal Neoplasms, Leukemia, Myeloid, Acute

NCT06158828 2026-02-13

ABCD-NK

Other hematologic neoplasm

68 enrolled

Leukemia, Myeloid, Acute

NCT06598371 2026-02-11

A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors

Phase 1/2 Active not recruiting

141 enrolled

Other solid neoplasm

Select Advanced Solid Tumors

NCT03474497 2026-01-29

UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade

18 enrolled 13 charts

DermatologicGenitourinaryHead & NeckThoracic

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma

NCT06961357 2025-12-03

Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma

36 enrolled

Uveal Melanoma, Melanoma

NCT05296564 2025-10-02

Anti-NY-ESO-1 TCR-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers

BreastCNSDermatologicGynecologicSarcomaThoracic

3 enrolled

Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasm Metastasis, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Sarcoma, Synovial, Triple Negative Breast Neoplasms

NCT06532799 2024-11-12

BAH250

75 enrolled

Gastrointestinal

Adenocarcinoma, Esophageal Neoplasms, Stomach Neoplasms

NCT06532812 2024-11-12

BAH249

Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

NCT06530303 2024-11-05

BAH248

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT06640582 2024-11-05

BAH2472

CNS

Brain Neoplasms, Glioblastoma, Glioma, Meningioma

NCT06538012 2024-10-15

BAH2472

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03658785 2024-08-13

Immunotherapy for the Treatment of Advanced Solid Tumor

40 enrolled

Neoplasm Metastasis, Recurrence

NCT03098355 2024-03-18

Interleukin-2 Following 4SCAR19/22 T Cells Targeting Refractory and/or Recurrent B Cell Malignancies

LymphoidOther hematologic neoplasm

Leukemia, B-Cell, Lymphoma, B-Cell

NCT01898793 2024-01-17

Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Phase 1/2 Terminated

89 enrolled 17 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT05981001 2023-08-08

Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer

170 enrolled

Breast

Breast Neoplasms

NCT05981014 2023-08-08

Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer

196 enrolled

Breast

Breast Neoplasms

NCT03287674 2023-03-01

TIL Therapy in Combination With Checkpoint Inhibitors for Metastatic Ovarian Cancer

7 enrolled 10 charts

Gynecologic

Ovarian Neoplasms

NCT00945269 2022-11-15

Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma

Phase 1/2 Terminated

3 enrolled

Melanoma

NCT03374839 2022-05-06

Nivo-TIL

11 enrolled

Melanoma

NCT02989714 2021-07-13

Phase Ib/II Trial of Interleukin-2 and PD-1 Checkpoint Inhibitor, Nivolumab In Metastatic Clear Cell Renal Cell Cancer

13 enrolled 11 charts

Carcinoma, Renal Cell

NCT01701479 2020-07-14

LTI

288 enrolled

CNS

Neuroblastoma

NCT02354690 2020-03-23

Vemurafenib and TIL Therapy for Metastatic Melanoma

13 enrolled 12 charts

Melanoma

NCT02379195 2020-01-22

Peginterferon and TIL Therapy for Metastatic Melanoma

12 enrolled 10 charts

Melanoma

NCT01550367 2020-01-02

Study of Hydroxychloroquine and Aldesleukin in Renal Cell Carcinoma Patients (RCC)

30 enrolled 20 charts

Carcinoma, Renal Cell

NCT03111901 2019-07-12

UVA-AM-002

DermatologicGenitourinary

Carcinoma, Renal Cell, Melanoma

NCT03297463 2018-08-01

Radiation Therapy With Combination Immunotherapy for Relapsed/Refractory Metastatic Melanoma

CNSDermatologic

Brain Neoplasms, Melanoma

NCT00303667 2017-12-28

Donor Natural Killer Cells and Aldesleukin in Treating Patients w/High Risk AML Undergoing Donor Stem Cell Transplant

Other hematologic neoplasm

50 enrolled 13 charts

Leukemia, Myeloid, Acute

NCT00625729 2017-12-28

Donor Natural Killer Cell Infusion, Rituximab, Aldesleukin, and Chemotherapy in Treating Patients With Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia

Phase 1/2 Terminated

6 enrolled 10 charts

LymphoidOther hematologic neoplasm

Burkitt Lymphoma, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell

NCT03171220 2017-06-06

NRT-01

40 enrolled

Other solid neoplasm

Advanced Malignant Solid Tumor

NCT03044743 2017-05-02

PD-1 Knockout EBV-CTLs for Advanced Stage Epstein-Barr Virus (EBV) Associated Malignancies

GastrointestinalHead & NeckLymphoid

20 enrolled

Nasopharyngeal Carcinoma, Hodgkin Disease, Stomach Neoplasms, Lymphoma, T-Cell, Lymphoma, Large B-Cell, Diffuse

NCT00871481 2017-04-19

Laboratory-Treated T Cells and Ipilimumab in Treating Patients With Metastatic Melanoma

10 enrolled

Melanoma

NCT00052520 2017-03-29

Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation

Classical hematologyLymphoidMyeloidOther hematologic neoplasm

37 enrolled

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02315118 2016-06-22

Pilot Study of Autologous T Lymphocytes With ADCC in Patients With CD20-Positive B-Cell Malignancies

LymphoidOther hematologic neoplasm

18 enrolled

Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell

NCT00937625 2015-08-18

T-cell Based Immunotherapy for of Melanoma

31 enrolled

Melanoma

NCT01743157 2013-08-29

BBI

24 enrolled

Melanoma

NCT01409187 2012-01-26

IPI-Biotherapy for Patients Previously Treated With Cytotoxic Drugs With Metastatic Melanoma

Melanoma

NCT00277017 2011-09-27

Combination Therapy With 5-Fluorouracil, Interferon-an Interleukin-2, & Thalidomide for Metastatic, Advanced or Recurrent Renal Cell Carcinoma

15 enrolled

Carcinoma, Renal Cell, Neoplasms

NCT00197912 2010-04-26

Dendritic Cell Based Therapy of Malignant Melanoma

25 enrolled

Melanoma

NCT00283829 2007-11-29

Immunotherapy After Chemotherapy for Patients With Hormone Refractory Metastatic Prostate Cancer

30 enrolled