Clinical Trials Browser

Colonic Neoplasms, Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT04141995 2025-08-07

FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer

Phase 2 Terminated

11 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT05330429 2025-07-01

ELEVATE CRC

Phase 2 Terminated

77 enrolled 22 charts

Gastrointestinal

Colorectal Neoplasms

NCT05461794 2025-06-13

Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma

Phase 2 Terminated

96 enrolled 17 charts

Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT03387592 2025-03-10

SENECA

Phase 2 Terminated

53 enrolled

Endocrine

Carcinoma, Neuroendocrine

NCT03822936 2025-02-13

PIOPPO

Phase 2 Terminated

30 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT02485834 2025-01-20

FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer

Phase 2 Terminated

5 enrolled 11 charts

Gastrointestinal

Stomach Neoplasms

NCT05546411 2024-12-17

A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer

Phase 2 Terminated

8 enrolled 11 charts

Gastrointestinal

Pancreatic Neoplasms

NCT05039944 2024-07-18

SI-B001 as a Single Agent or in Combination With Chemotherapy in the Treatment of Digestive System Malignancies

Phase 2 Terminated

7 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT02842580 2024-07-10

HIGH-LIGHT

Phase 2 Terminated

21 enrolled 12 charts

Gastrointestinal

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT05148195 2024-03-13

A Phase II Study of Envofolimab and BD0801 With/Without Chemotherapy in Patients With Advanced Solid Tumors

Phase 2 Terminated

86 enrolled

Other solid neoplasm

Advanced Solid Tumor

NCT01897454 2023-12-05

Gemcitabine Hydrochloride, and Radiation Therapy in Patients With Borderline Resectable Pancreatic Cancer

Phase 2 Terminated

23 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms

NCT03251417 2023-02-01

Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell Carcinoma

Phase 2 Terminated

11 enrolled

Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT03099265 2022-10-27

Neoadjuvant Modified FOLFIRINOX and Stereotactic Body Radiation Therapy in Borderline Resectable Pancreatic Adenocarcinoma

Phase 2 Terminated

9 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms

NCT00314353 2021-10-06

Study of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the Colon

Phase 2 Terminated

7 enrolled 5 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT03368859 2021-02-09

A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab

Phase 2 Terminated

70 enrolled 12 charts

Gastrointestinal

Intestinal Neoplasms, Neoplasms, Colorectal Neoplasms

NCT02405585 2020-05-28

Immunotherapy and SBRT Study in Borderline Resectable Pancreatic Cancer

Phase 2 Terminated

10 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT01609231 2020-05-04

MK-0646-025

Phase 2 Terminated

11 enrolled 8 charts

Gastrointestinal

Rectal Neoplasms

NCT02275806 2019-08-21

Cisplatin/Irinotecan With Concurrent Radiation for Inoperable NSCLC

Phase 2 Terminated

4 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01479465 2019-04-17

Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma

Phase 2 Terminated

266 enrolled 15 charts

Gastrointestinal

Neoplasms, Colorectal Neoplasms

NCT01760252 2019-03-15

Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Pancreatic Adenocarcinoma Protocol

Phase 2 Terminated

17 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT00465907 2019-02-11

Study of Weekly Paclitaxel, Carboplatin and Irinotecan to Treat Lung Cancer

Phase 2 Terminated

7 enrolled

Thoracic

Lung Neoplasms

NCT01925274 2019-01-08

A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal Cancer

Phase 2 Terminated

19 enrolled 32 charts

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT00100828 2018-12-06

Irinotecan in Treating Patients With Metastatic or Inoperable Thyroid Cancer

Phase 2 Terminated

6 enrolled 4 charts

Head & Neck

Head and Neck Neoplasms, Thyroid Neoplasms, Carcinoma, Medullary

NCT00276744 2018-10-24

Individualized Drug Treatment for Treating Patients With Pancreatic Cancer

Phase 2 Terminated

249 enrolled 4 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02508077 2018-08-16

FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer

Phase 2 Terminated

1 enrolled 4 charts

Gastrointestinal

Colorectal Neoplasms

NCT01608464 2018-08-10

Pre-op Chemo-RT w/CDDP/5FU vs Chemo w/ Docetaxel/Irinotecan in PET Non Responder Resectable Esophagus Cancer

Phase 2 Terminated

170 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT01935947 2018-07-27

Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

Phase 2 Terminated

17 enrolled 10 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02241551 2018-07-26

Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer

Phase 2 Terminated

2 enrolled 7 charts

Tumor-Agnostic

Neoplasms

NCT00089102 2018-07-16

Gemcitabine and Irinotecan in Treating Patients With Locally Advanced Unresectable or Metastatic Kidney Cancer

Phase 2 Terminated

9 enrolled 8 charts

Genitourinary

Carcinoma, Renal Cell, Kidney Neoplasms

NCT02345460 2018-07-13

Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study

Phase 2 Terminated

1 enrolled 5 charts

Gastrointestinal

Pancreatic Neoplasms

NCT00089128 2018-07-12

Gemcitabine and Irinotecan in Treating Patients With Locally Advanced or Metastatic Bladder Cancer

Phase 2 Terminated

16 enrolled 4 charts

Genitourinary

Urinary Bladder Neoplasms

NCT00642603 2018-03-29

A Study of Xeloda (Capecitabine) in Combination With Avastin + Short Course Chemotherapy in Patients With Metastatic Colorectal Cancer

Phase 2 Terminated

41 enrolled 6 charts

Gastrointestinal

Colorectal Neoplasms

NCT01359007 2018-03-09

FOLFIRINOX in Patients With Inoperable Pancreatic Cancer

Phase 2 Terminated

5 enrolled 7 charts

Gastrointestinal

Adenocarcinoma of Pancreas

NCT00848783 2018-01-08

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Phase 2 Terminated

8 enrolled 9 charts

Gastrointestinal

Esophageal Neoplasms, Stomach Neoplasms

NCT01313884 2017-11-24

Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma

Phase 2 Terminated

3 enrolled 7 charts

Sarcoma

Bone Neoplasms, Sarcoma, Ewing

NCT01688336 2017-10-06

FOLFIRINOX for Unresectable Locally Advanced and Borderline Resectable Pancreatic Cancer

Phase 2 Terminated

9 enrolled 14 charts

Gastrointestinal

Pancreatic Neoplasms

NCT01765582 2017-09-18

STEAM

Phase 2 Terminated

280 enrolled 15 charts

Gastrointestinal

Colorectal Neoplasms

NCT02316496 2017-08-01

REGAIN

Phase 2 Terminated

2 enrolled

Tumor-Agnostic

Neoplasm Metastasis, Neoplasms

NCT00808899 2017-05-30

Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma

Phase 2 Terminated

4 enrolled 5 charts

CNS

Neuroblastoma

NCT00449163 2017-05-11

Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

Phase 2 Terminated

25 enrolled 10 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00588900 2017-04-05

Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab

Phase 2 Terminated

5 enrolled 5 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00127036 2017-03-23

Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)

Phase 2 Terminated

65 enrolled 8 charts

Gastrointestinal

Adenocarcinoma, Colonic Neoplasms, Rectal Neoplasms

NCT00360828 2017-03-23

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

Phase 2 Terminated

10 enrolled 6 charts

CNS

Astrocytoma, Brain Neoplasms, Glioma, Neurologic Manifestations, Oligodendroglioma

NCT00040391 2016-12-01

A Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal Cancer

Phase 2 Terminated

Gastrointestinal

Diarrhea, Colorectal Neoplasms

NCT01060423 2016-10-26

DEBIRITUX

Phase 2 Terminated

8 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT01322815 2016-08-15

A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLFOX or FOLFIRI

Phase 2 Terminated

11 enrolled 8 charts

Gastrointestinal

Colonic Neoplasms, Neoplasm Metastasis

NCT01320683 2016-07-19

Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Phase 2 Terminated

1 enrolled 2 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms

NCT00216086 2016-06-06

Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer

Phase 2 Terminated

22 enrolled 10 charts

Gastrointestinal

Rectal Neoplasms

NCT02060955 2016-06-06

Randomized Phase 2 Study to Investigate Efficacy of ALECSAT in Patients With GBM Measured Compared to Avastin/Irinotecan

Phase 2 Terminated

25 enrolled

CNS

Glioblastoma, Recurrence

Clinical Trials

A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer

FOLFIRINOX With Digoxin in Patients With Resectable Pancreatic Cancer

ELEVATE CRC

Study To Investigate the Efficacy and Safety of Sitravatinib in Combination With Tislelizumab in Participants With Esophageal Squamous Cell Carcinoma

SENECA

PIOPPO

FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer

A Trial of NIS793 With FOLFIRINOX in Pancreatic Cancer

SI-B001 as a Single Agent or in Combination With Chemotherapy in the Treatment of Digestive System Malignancies

HIGH-LIGHT

A Phase II Study of Envofolimab and BD0801 With/Without Chemotherapy in Patients With Advanced Solid Tumors

Gemcitabine Hydrochloride, and Radiation Therapy in Patients With Borderline Resectable Pancreatic Cancer

Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell Carcinoma

Neoadjuvant Modified FOLFIRINOX and Stereotactic Body Radiation Therapy in Borderline Resectable Pancreatic Adenocarcinoma

Study of Bevacizumab Combined With Capecitabine and Either Oxaliplatin or Irinotecan as First Course of Treatment for Patients With Colorectal Cancer That Has Spread Beyond the Colon

A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab

Immunotherapy and SBRT Study in Borderline Resectable Pancreatic Cancer

MK-0646-025

Cisplatin/Irinotecan With Concurrent Radiation for Inoperable NSCLC

Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma

Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Pancreatic Adenocarcinoma Protocol

Study of Weekly Paclitaxel, Carboplatin and Irinotecan to Treat Lung Cancer

A Study Of PF-05212384 Plus Irinotecan Vs Cetuximab Plus Irinotecan In Patients With KRAS And NRAS Wild Type Metastatic Colorectal Cancer

Irinotecan in Treating Patients With Metastatic or Inoperable Thyroid Cancer

Individualized Drug Treatment for Treating Patients With Pancreatic Cancer

FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer

Pre-op Chemo-RT w/CDDP/5FU vs Chemo w/ Docetaxel/Irinotecan in PET Non Responder Resectable Esophagus Cancer

Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancer

Phase II Neoadjuvant Chemotheraphy (Gemcitabine and Nab-Paclitaxel vs. mFOLFIRINOX) and Sterotatic Body Radiation Therapy for Borderline Resectable Pancreatic Cancer

Gemcitabine and Irinotecan in Treating Patients With Locally Advanced Unresectable or Metastatic Kidney Cancer

Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study

Gemcitabine and Irinotecan in Treating Patients With Locally Advanced or Metastatic Bladder Cancer

A Study of Xeloda (Capecitabine) in Combination With Avastin + Short Course Chemotherapy in Patients With Metastatic Colorectal Cancer

FOLFIRINOX in Patients With Inoperable Pancreatic Cancer

Irinotecan/Cisplatin, Potentially Curative Surgery With or Without Floxuridine, Followed by Capecitabine for Stomach and Gastro-esophageal Junction (GEJ) Cancers

Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma

FOLFIRINOX for Unresectable Locally Advanced and Borderline Resectable Pancreatic Cancer

STEAM

REGAIN

Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma

Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab

Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

A Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal Cancer

DEBIRITUX

A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLFOX or FOLFIRI

Combination Chemotherapy and Bevacizumab Before Surgery and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer

Capecitabine + Irinotecan Followed by Combined Modality Capecitabine and Radiation in Locally Advanced Rectal Cancer

Randomized Phase 2 Study to Investigate Efficacy of ALECSAT in Patients With GBM Measured Compared to Avastin/Irinotecan