Clinical Trials Browser

Phase 1 × Itraconazole × Clear all

NCT03460977 2026-03-13

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Phase 1 Recruiting

LymphoidThoracic

Lymphoma, Follicular, Recurrence, Small Cell Lung Carcinoma

NCT07402915 2026-02-11

Drug-drug Interaction Study With AZD5335 and Itraconazole in Participants With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Phase 1 Recruiting

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT05372367 2026-02-03

A Study in People With Advanced Cancer to Test Whether the Amount of BI 907828 in the Blood is Influenced by Taking an OATP Inhibitor or a CYP3 Inhibitor

Phase 1 Completed

Other solid neoplasm

Solid Tumors

NCT06084481 2026-01-20

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

Phase 1 Active not recruiting

BreastGastrointestinalHead & Neck

Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma, Biliary Tract Neoplasms, Carcinoma, Hepatocellular, Triple Negative Breast Neoplasms

NCT07186452 2026-01-16

Evaluation of the Effect of Itraconazole on the Pharmacokinetics of HS-20093 in Patients With Advanced Solid Tumors

Phase 1 Recruiting

Other solid neoplasm

Advanced Solid Tumors

NCT06400472 2026-01-14

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

Phase 1 Recruiting

BreastGastrointestinalGynecologicThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Uterine Cervical Neoplasms, Lung Neoplasms, Ovarian Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms, Endometrial Neoplasms, Triple Negative Breast Neoplasms

NCT07229560 2026-01-14

A Trial of Itraconazole Effect on HRS-8080 Pharmacokinetics in Healthy Participants

Phase 1 Completed

Breast Neoplasms

NCT07160738 2025-11-28

A Study to Learn About How the Study Medicines Called Itraconazole and Probenecid Change How the Body Processes PF-07220060

Phase 1 Recruiting

Breast Neoplasms

NCT06965881 2025-11-21

Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults

Phase 1 Terminated

Focal Cortical Dysplasia, Tuberous Sclerosis

NCT02157883 2025-11-19

Study to Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of AZD9291, in Patients With EGFR Positive Non-small Cell Lung Cancer. Patients Will be Chosen From Those Who Have Already Been Prescribed an EGFR TKI Medicine (Such as Iressa or Tarceva)

Phase 1 Completed

39 enrolled 18 charts

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT05609253 2025-08-08

Itraconazole to Prevent Recurrent Barrett's Esophagus

Phase 1 Active not recruiting

Gastrointestinal

Barrett Esophagus

NCT02875223 2025-04-20

A Safety and Efficacy Study of CC-90011 in Participants With Relapsed and/or Refractory Solid Tumors and Non-Hodgkin's Lymphomas

Phase 1 Terminated

75 enrolled 35 charts

Lymphoma, Non-Hodgkin, Neoplasms

NCT06710990 2025-03-28

Investigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast Cancer

Phase 1 Recruiting

Advanced Breast Cancer

NCT04537715 2025-02-19

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Phase 1 Completed

42 enrolled 39 charts

LymphoidOther hematologic neoplasmOther solid neoplasmSarcomaThoracic

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mesothelioma, Sarcoma, Sarcoma, Synovial, Lymphoma, Large B-Cell, Diffuse, Rhabdoid Tumor, Hematologic Neoplasms

NCT05357820 2024-11-21

A Study of AB-106 in Chinese Healthy Adult Men Evaluated the Effects of Itraconazole and Rifampicin on AB-106 PK

Phase 1 Completed

Other solid neoplasm

Solid Tumor

NCT03994211 2024-10-26

Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer

Phase 1 Completed

25 enrolled 33 charts

Other solid neoplasm

Solid Tumor

NCT05679388 2024-09-19

A Study of Extending Relugolix Dosing Intervals Through Addition of Itraconazole or Ritonavir in Prostate Cancer Patients

Phase 1 Terminated

Prostatic Neoplasms

NCT05573724 2024-06-18

Drug-drug Interaction Study With AZD5305 and Itraconazole in Patients With Advanced Solid Malignancies

Phase 1 Completed

Neoplasms

NCT05602597 2024-03-06

HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI

Phase 1 Completed

Lymphoma, Recurrence

NCT03383692 2023-12-11

Study of DS-8201a for Participants With Advanced Solid Malignant Tumors

Phase 1 Completed

40 enrolled 20 charts

Neoplasm Metastasis, Neoplasms

NCT01772563 2023-09-01

Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours

Phase 1 Completed

28 enrolled 10 charts

Neoplasms

NCT05720767 2023-03-01

HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study

Phase 1 Completed

Lymphoma, Recurrence

NCT05551897 2023-01-06

A Study to Assess the Pharmacokinetics of Camizestrant (AZD9833) When Administered Alone and in Combination With Itraconazole

Phase 1 Completed

Breast Neoplasms

NCT04959266 2022-09-16

A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

Phase 1 Terminated

Other solid neoplasm

Advanced Solid Tumours

NCT04584515 2021-08-24

IMP4297 DDI (Drug-Drug Interaction)Trial in Healthy Male Volunteers

Phase 1 Completed

Other solid neoplasm

Solid Tumor

NCT03077607 2021-06-30

A Study to Evaluate the Effect of Itraconazole and Rifampin on the Pharmacokinetics of Talazoparib in Patients With Advanced Solid Tumors

Phase 1 Completed

36 enrolled 28 charts

Other solid neoplasm

Advanced Solid Tumors

NCT04712396 2021-04-09

A Study to Assess How Itraconazole Affects the Uptake and Elimination of Capivasertib in the Body

Phase 1 Completed

BreastGenitourinary

Healthy Volunteers (Intended Indication: Metastatic Patients With Triple Negative or HR+ Breast Cancer, or Hormone Sensitive Prostate Cancer)

NCT02253420 2020-12-14

COPANLISIB (BAY80-6946) Drug-drug Interaction and Cardiovascular Safety Study in Advanced Solid Tumor and Non-Hodgkin's Lymphoma Patients

Phase 1 Completed

Lymphoma, Non-Hodgkin

NCT02706535 2020-11-16

A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential

Phase 1 Completed

Neoplasms

NCT02824042 2020-07-31

Thorough ECG (Electrocardiogram) and Drug Interaction Study With Anetumab Ravtansine and Itraconazole

Phase 1 Completed

Medical Oncology

NCT02608034 2020-02-12

A Study to Investigate the Effect of Itraconazole and Rifampin on Pharmacokinetics (PK) of Vemurafenib at Steady State

Phase 1 Completed

Melanoma

NCT04121910 2020-01-23

A Study to Evaluate the Amount of Drug That Becomes Available in the Blood Circulation When Savolitinib is Administered Alone and in Combination With Itraconazole

Phase 1 Completed

Other solid neoplasm

Solid Tumour

NCT02259010 2019-09-20

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of Alisertib in Participants With Advanced Solid Tumors or Relapsed/Refractory Lymphoma

Phase 1 Completed

24 enrolled 26 charts

Lymphoma

NCT02122770 2019-01-07

Effects of Fluconazole and Itraconazole CYP3A-Mediated Inhibition on the Pharmacokinetics, Safety, and Tolerability of MLN4924 in Participants With Advanced Solid Tumors

Phase 1 Completed

51 enrolled 30 charts

Other solid neoplasm

Advanced Solid Tumors

NCT03119077 2018-05-17

Single Ascending Dose, First-in-Human Study on Safety, Tolerability and Pharmacokinetics of BAY1161116

Phase 1 Terminated

Polycystic Ovary Syndrome

NCT02401295 2017-02-23

ATRA, Celecoxib, and Itraconazole as Maintenance

Phase 1 Completed

Multiple Myeloma

NCT01900028 2016-10-17

To Assess the Effect of Itraconazole (a CYP3A4 Inhibitor) on the Pharmacokinetics of Olaparib, and the Effect of Olaparib on QT Interval Following Oral Dosing of a Tablet Formulation to Patients With Advanced Solid Tumours

Phase 1 Completed

Neoplasms

NCT02457351 2016-05-23

Roniciclib (BAY 1000394) Drug-Drug Interaction (DDI) Study

Phase 1 Completed

Medical Oncology

NCT02093728 2015-06-30

To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

Phase 1 Completed

Other solid neoplasm

Solid Tumours

NCT01409018 2013-11-19

Pharmacokinetics of Itraconazole in Pediatric Cancer Patients

Phase 1 Completed

Invasive Fungal Infections, Neoplasms