Clinical Trials

87 enrolled 23 charts

Breast Neoplasms

NCT01306045 2024-10-01

Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies

647 enrolled 17 charts

Thoracic

Carcinoma, Non-Small-Cell Lung, Thymoma, Small Cell Lung Carcinoma

NCT01622868 2023-10-17

Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer

143 enrolled 24 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT01711658 2023-10-17

TRYHARD

142 enrolled 22 charts

Head & Neck

Head and Neck Neoplasms

NCT00841828 2023-03-31

Trastuzumab Versus Lapatinib as Neoadjuvant Treatment for Her2+ Patients

102 enrolled 10 charts

Breast Neoplasms

NCT00436566 2022-08-05

Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

122 enrolled 22 charts

Breast Neoplasms, Breast Neoplasms, Male, Cardiotoxicity

NCT00444535 2021-10-25

Lapatinib and Bevacizumab for Metastatic Breast Cancer

52 enrolled 13 charts

Breast Neoplasms, Osteitis Deformans

NCT00206427 2021-09-29

GW

49 enrolled 7 charts

Breast Neoplasms, Neoplasms

NCT00883688 2020-08-26

Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma

24 enrolled 5 charts

CNS

Brain Neoplasms, Ependymoma, Neuroectodermal Tumors, Primitive, Glioma, Subependymal

NCT02362958 2020-07-15

A Multi-Center Study of Lapatinib in Patients With Trastuzumab-refractory Metastatic Breast Cancer

159 enrolled

HER2 Positive Breast Cancer

NCT00684983 2020-03-24

Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer

64 enrolled 13 charts

Insulin-Like Growth Factor I, Resistance To, Breast Neoplasms

NCT00574171 2019-12-18

Phase II Trial of Lapatinib & Capecitabine for Patients With Refractory Advanced Colorectal Adenocarcinoma

29 enrolled 6 charts

Colorectal Neoplasms

NCT00263588 2019-12-12

Lapatinib for Brain Metastases In ErbB2-Positive Breast Cancer

242 enrolled 19 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms, Neoplasms

NCT00820872 2019-10-21

Docetaxel, Carboplatin, Trastuzumab, and Lapatinib in Treating Patients With Early Stage Breast Cancer

30 enrolled 6 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00096447 2019-07-24

Lapatinib in Treating Patients With Recurrent or Persistent Endometrial Cancer

31 enrolled 13 charts

Gynecologic

Endometrial Neoplasms

NCT00113373 2019-07-24

Lapatinib in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Peritoneal Cancer

28 enrolled 11 charts

Gynecologic

Carcinoma, Ovarian Epithelial

NCT00826241 2019-03-22

Dose-Dense Temozolomide + Lapatinib for Recurrent Ependymoma

58 enrolled 11 charts

CNS

Brain Neoplasms, Ependymoma, Spinal Cord Neoplasms

NCT02142036 2019-03-13

MetAction

50 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT00320411 2019-01-31

GW572016 In Patients With ErbB2 Over - Expressing Advanced Or Metastatic Breast Cancer

62 enrolled 24 charts

Breast Neoplasms

NCT01973660 2018-09-19

PAMELA

151 enrolled

Breast Neoplasms

NCT00477464 2018-09-17

Lapatinib in Combination With Capecitabine in Japanese Patients With Metastatic Breast Cancer

51 enrolled 25 charts

Breast Neoplasms

NCT00777101 2018-08-09

Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancer

233 enrolled 16 charts

Breast Neoplasms, Neoplasm Metastasis

NCT01485926 2018-08-06

TCHL Phase II

120 enrolled

Breast Neoplasms

NCT00107003 2018-07-05

GW572016 to Treat Recurrent Malignant Brain Tumors

9 enrolled

CNSSarcoma

Brain Neoplasms, Glioblastoma, Glioma, Neoplasms, Gliosarcoma

NCT02015169 2018-01-17

Phase II Study of Neoadjuvant XELOX + Lapatinib in HER2(+) Gastric Cancer Patients With Liver Metastasis

32 enrolled

Stomach Neoplasms

NCT00118157 2017-12-04

Lapatinib and Tamoxifen in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous Tamoxifen

19 enrolled 6 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT02338245 2017-10-17

Study of ASLAN001 in Combination With Capecitabine in MBC That Has Failed on Prior Trastuzumab

200 enrolled

Breast Neoplasms

NCT01688609 2017-09-11

Lapatinib Ditosylate, Trastuzumab, Paclitaxel, and Surgery in Treating Patients With Breast Cancer

18 enrolled 7 charts

Breast Neoplasms

NCT01275859 2017-08-29

Neo-All-In

25 enrolled

Breast Neoplasms

NCT00721630 2017-08-15

Novel Capecitabine Dosing Schedule in Combination With Lapatinib, Based on the Norton-Simon Mathematical Method in Patients With HER2 Overexpressed/Amplified, Trastuzumab (Herceptin) -Refractory, Metastatic Breast Cancer

24 enrolled 8 charts

Breast Neoplasms

NCT00246753 2017-06-28

NRR

29 enrolled 8 charts

Genitourinary

Prostatic Neoplasms

NCT00111787 2017-05-31

Study Of Lapatinib In Combination With Paclitaxel In The Treatment Of Newly Diagnosed Inflammatory Breast Cancer

49 enrolled

Breast Neoplasms

NCT01013740 2017-05-31

VITAL

112 enrolled 15 charts

Breast Neoplasms, Neoplasms

NCT00482391 2017-05-12

Doxorubicin and Cyclophosphamide Followed by Paclitaxel, Trastuzumab, and Lapatinib in Treating Patients With HER2/Neu-Overexpressed Breast Cancer

95 enrolled 7 charts

Breast Neoplasms, Breast Neoplasms, Male

NCT00089999 2017-02-28

Lapatinib In Chemotherapy-Naive Or Metastatic Breast Cancer

138 enrolled 16 charts

Breast Neoplasms

NCT02342587 2017-02-17

Safety and Clinical Activity of Lapatinib in Patients With HER2-positive Refractory Advanced Cancer

7 enrolled

HER2-positive Refractory Advanced Cancer

NCT00524303 2016-11-11

Lapatinib +/- Trastuzumab In Addition To Standard Neoadjuvant Breast Cancer Therapy.

100 enrolled 14 charts

Breast Neoplasms

NCT00422903 2016-05-12

Letrozole In Combination With Lapatinib In Neoadjuvant Treatment Of Early Breast Cancer

92 enrolled 14 charts

Breast Neoplasms

NCT00429299 2016-03-22

CHERLOB

121 enrolled 16 charts

Breast Neoplasms

NCT00973739 2016-03-22

Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

21 enrolled 8 charts

CNS

Neurilemmoma, Neuroma, Acoustic, Neurofibromatosis 2

NCT00347919 2016-02-25

Pazopanib Plus Lapatinib Compared To Lapatinib Alone In Subjects With Advanced Or Metastatic Breast Cancer

189 enrolled 15 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00526669 2016-01-29

Study For Patients With Untreated Gastric Cancer Who Will Receive Capecitabine And Lapatinib

68 enrolled 16 charts

Neoplasm Metastasis, Neoplasms, Stomach Neoplasms

NCT00769470 2016-01-22

Docetaxel, Carboplatin, and Trastuzumab and/or Lapatinib in Treating Women With Stage I, Stage II, or Stage III Breast Cancer That Can Be Removed by Surgery

18 enrolled

Breast Neoplasms

NCT01068704 2015-10-12

Efficacy and Safety of BMS-690514 in Combination With Letrozole to Treat Metastatic Breast Cancer

4 enrolled

Breast Neoplasms

NCT00105950 2015-09-28

Study Of Lapatinib In Patients With Relapsed Or Refractory Inflammatory Breast Cancer

126 enrolled

Breast Neoplasms, Inflammatory Breast Neoplasms

NCT00694252 2015-09-28

Lapatinib and Circulating Tumor Cells in Breast Cancer

20 enrolled

Breast Neoplasms

NCT00387127 2015-06-25

Lapatinib Versus Placebo Given Concurrently With Cisplatin And Radiotherapy In Patients With Unresected Head And Neck Cancer

67 enrolled 18 charts

Head & Neck

Head and Neck Neoplasms

NCT00430781 2015-05-08

Pazopanib Plus Lapatinib Compared to Lapatinib Alone and Pazopanib Alone In Subjects With Metastatic Cervical Cancer

228 enrolled 21 charts

Gynecologic

Uterine Cervical Neoplasms, Neoplasms, Recurrence

NCT00107536 2015-04-29

Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer

26 enrolled 11 charts