Clinical Trials

Phase 2 Active not recruiting

Smoldering Multiple Myeloma

NCT01351896 2025-11-20

Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

49 enrolled 34 charts

Phase 1 Active not recruiting

Leukemia, Lymphocytic, Chronic, B-Cell

NCT01955499 2025-11-10

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

39 enrolled

Lymphoid

Lymphoma, Follicular, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT02911142 2025-07-28

Lenalidomide Combined With Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-associated Large Cell Lymphoma

Phase 1/2 Active not recruiting

17 enrolled 21 charts

Lymphoid

Lymphoma, B-Cell, Lymphoma, AIDS-Related, Lymphoma, Primary Effusion

NCT03941860 2025-05-23

Testing the Addition of Ixazomib/Placebo to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma, OPTIMUM Trial

Phase 3 Completed

1 enrolled 1 chart

Multiple Myeloma

NCT01553149 2025-01-07

Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma

75 enrolled 17 charts

CNS

Astrocytoma, Neurofibromatosis 1, Optic Nerve Glioma

NCT02728102 2024-05-07

Dendritic Cell/Myeloma Fusion Vaccine for Multiple Myeloma (BMT CTN 1401)

203 enrolled 25 charts

Hematologic Diseases, Multiple Myeloma

NCT01886859 2022-09-26

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

27 enrolled

Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, B-Cell

NCT00352365 2022-02-11

Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia

Other hematologic neoplasm

41 enrolled 11 charts

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Basophilic, Acute, Leukemia, Eosinophilic, Acute, Leukemia, Myelomonocytic, Acute

NCT01057121 2022-02-08

Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma

Phase 1/2 Completed

38 enrolled 11 charts

Sarcoma

AIDS-related Kaposi sarcoma, Sarcoma, Kaposi, HIV Infections

NCT01222754 2022-01-03

Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

29 enrolled

CNS

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Brain Neoplasms, Glioma

NCT01109004 2021-12-09

BMT CTN 0702

Phase 3 Completed

758 enrolled 21 charts

Hematologic Diseases, Multiple Myeloma, Disease Progression

NCT01208051 2021-07-15

Cediranib Maleate With or Without Lenalidomide for the Treatment of Thyroid Cancer

Phase 1/2 Completed

127 enrolled 18 charts

EndocrineHead & Neck

Thyroid cancer, Hurthle cell, Thyroid Cancer, Papillary, Adenocarcinoma, Follicular

NCT02322320 2020-05-11

Continued, Long-Term Follow-Up and Lenalidomide Maintenance Therapy for Patients on BMT CTN 0702 Protocol (BMT CTN 07LT)

Phase 3 Completed

273 enrolled 16 charts

Hematologic Diseases, Multiple Myeloma, Disease Progression

NCT01629082 2019-12-17

Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

MyeloidOther hematologic neoplasm

4 enrolled

Bone Marrow Diseases, Myelodysplastic Syndromes, Neutropenia, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT01647165 2019-12-12

Phase II Study of Subcutaneous (SC) Bortezomib, Lenalidomide and Dexamethasone for Relapsed and/or Refractory Multiple Myeloma; Followed by SC Bortezomib Maintenance

Phase 2 Withdrawn

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00553644 2018-10-30

Bortezomib and Lenalidomide in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

53 enrolled 8 charts

Lymphoid

Lymphoma, Mantle-Cell

NCT00942578 2018-10-11

A Phase 2 Trial of Bevacizumab, Lenalidomide, Docetaxel, and Prednisone (ART-P) for Treatment of Metastatic Castrate-Resistant Prostate Cancer

63 enrolled 23 charts

Genitourinary

Prostatic Neoplasms

NCT01675141 2018-02-05

Lenalidomide Maintenance Therapy for Multiple Myeloma

Phase 2 Terminated

11 enrolled 7 charts

Multiple Myeloma

NCT01254578 2017-09-25

Lenalidomide After Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancers

DermatologicLymphoidOther hematologic neoplasm

17 enrolled

Burkitt Lymphoma, Immunoblastic Lymphadenopathy, Leukemia, Hairy Cell, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Acute, Lymphoma, T-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Intraocular Lymphoma

NCT00410605 2017-09-01

Bevacizumab, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Stage II or III Multiple Myeloma

39 enrolled 10 charts

Multiple Myeloma

NCT00482911 2017-03-27

Lenalidomide, Sunitinib, and Cyclophosphamide in Treating Patients With Stage IV Eye Melanoma

Phase 2 Terminated

12 enrolled 10 charts

Dermatologic

Uveal Melanoma

NCT00109005 2017-01-02

Lenalidomide (Revlimid) to Treat Advanced Ocular Melanoma

17 enrolled 11 charts

Dermatologic

Uveal Melanoma, Melanoma

NCT00522392 2015-06-26

Bortezomib and Dexamethasone With or Without Lenalidomide in Treating Patients With Multiple Myeloma Previously Treated With Dexamethasone

Phase 3 Terminated

48 enrolled 9 charts

Multiple Myeloma

NCT01271283 2015-06-04

Lenalidomide in Treating Patients With High-Risk Chronic Lymphocytic Leukemia

Phase 2 Withdrawn

Leukemia, Lymphocytic, Chronic, B-Cell

NCT00036894 2015-04-30

CC-5013 in Treating Patients With Recurrent Glioma

CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00735930 2015-04-02

Lenalidomide and Alvocidib in Treating Patients With Relapsed or Refractory B-cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Classical hematologyLymphoidOther hematologic neoplasm

39 enrolled

Anemia, Thrombocytopenia, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Prolymphocytic

NCT01132586 2014-12-23

Lenalidomide, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Other hematologic neoplasm

61 enrolled

Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute, Leukemia, Myelomonocytic, Acute

NCT00104962 2014-06-11

Lenalidomide in Treating Young Patients With Relapsed or Refractory Solid Tumors or Myelodysplastic Syndromes

24 enrolled

Classical hematology

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts

NCT00227591 2014-05-21

Lenalidomide and Prednisone in Treating Patients With Myelofibrosis

48 enrolled 7 charts

Myeloid

Polycythemia Vera, Thrombocythemia, Essential, Primary Myelofibrosis

NCT00439231 2014-01-13

Lenalidomide in Previously Treated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

33 enrolled 8 charts

Leukemia, Lymphocytic, Chronic, B-Cell

NCT01307592 2014-01-10

Gemcitabine Hydrochloride, Rituximab, Oxaliplatin, and Lenalidomide in Treating Patients With Relapsed or Refractory, Aggressive Non-Hodgkin Lymphoma

Phase 2 Unknown

70 enrolled

Burkitt Lymphoma, Lymphoma, Lymphoma, Follicular, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Peripheral, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00100880 2013-09-30

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

45 enrolled

CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00398515 2013-09-30

Lenalidomide and Temsirolimus in Treating Patients With Previously Treated Multiple Myeloma

25 enrolled

Multiple Myeloma

NCT00031941 2012-03-15

CC-5013 in Treating Patients With Cancer That Has Not Responded to Previous Therapy