Clinical Trials Browser

Breast Neoplasms

NCT02767661 2026-02-27

MECCA

Phase 3 Completed

263 enrolled

Breast

Breast Neoplasms

NCT07143682 2025-12-16

Letrozole Step up Protocol for Ovulation Induction in Infertile Women With Polycystic Ovary Syndrome

Phase 3 Completed

70 enrolled

Infertility, Polycystic Ovary Syndrome

NCT03079011 2025-11-18

PADA-1

Phase 3 Completed

1,017 enrolled

Breast

Breast Neoplasms

NCT02297438 2025-10-27

A Study Of Palbociclib (PD-0332991) + Letrozole VS. Placebo+ Letrozole For 1st Line Treatment Of Asian Postmenopausal Women With ER+/HER2- Advanced Breast Cancer [PALOMA-4]

Phase 3 Completed

340 enrolled 29 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT03778931 2025-09-15

EMERALD

Phase 3 Completed

478 enrolled 16 charts 1 FDA

Breast

Breast Neoplasms

NCT00601900 2025-05-23

Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage IIIB or Stage IV Breast Cancer

Phase 3 Completed

394 enrolled 11 charts

Breast

Breast Neoplasms

NCT00265759 2025-04-23

Exemestane, Letrozole, or Anastrozole in Treating Postmenopausal Women Who Are Undergoing Surgery for Stage II or Stage III Breast Cancer

Phase 3 Completed

622 enrolled 18 charts

Breast

Breast Neoplasms

NCT00949598 2025-02-13

Letrozole or Tamoxifen Citrate in Treating Older Postmenopausal Women Undergoing Surgery for Breast Cancer

Phase 3 Completed

177 enrolled

Breast

Breast Neoplasms

NCT01740427 2024-11-14

PALOMA-2

Phase 3 Completed

666 enrolled 22 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT03439046 2024-08-01

BioItaLEE

Phase 3 Completed

287 enrolled

Breast

Breast Neoplasms, Hereditary Sensory and Autonomic Neuropathies

NCT06486870 2024-07-05

Comparison Between Two Ovulation Induction Therapies and LOD on Clinical Outcomes in CC-Resistant PCOS Women

Phase 3 Completed

183 enrolled

Polycystic Ovary Syndrome

NCT06403488 2024-05-08

Letrozole Dose Increments in PCOS Patients Resistant to Letrozole

Phase 3 Completed

102 enrolled

Polycystic Ovary Syndrome

NCT02278120 2024-03-12

MONALEESA-7

Phase 3 Completed

672 enrolled 16 charts 1 FDA

Breast

Advanced Metastatic Breast Cancer

NCT02941926 2023-10-24

COMPLEEMENT-1

Phase 3 Completed

3,246 enrolled 11 charts

Breast

Breast Neoplasms

NCT02600923 2022-01-20

Palbociclib Plus Letrozole For Postmenopausal Women With HR(+) HER2(-) Advanced Breast Cancer For Whom Letrozole Is Deemed Appropriate

Phase 3 Completed

131 enrolled 12 charts

Breast

Breast Neoplasms

NCT03096847 2021-10-11

Study for Women and Men With Hormone-receptor Positive Locally Advanced or Metastatic Breast Cancer

Phase 3 Completed

502 enrolled 20 charts

Breast

Breast Neoplasms, Osteitis Deformans

NCT02491320 2021-06-23

PCOSAPct

Phase 3 Completed

384 enrolled

Polycystic Ovary Syndrome

NCT00073528 2021-02-24

Study Comparing Lapatinib (GW572016) And Letrozole Versus Letrozole In Subjects With Advanced Or Metastatic Breast Cancer

Phase 3 Completed

1,286 enrolled 41 charts

Breast

Breast Neoplasms

NCT02511639 2020-12-03

MAIN-A

Phase 3 Completed

110 enrolled

Breast

Breast Cancer Metastatic

NCT00003140 2020-09-16

Letrozole After Tamoxifen in Treating Women With Breast Cancer

Phase 3 Completed

5,187 enrolled

Breast

Breast Neoplasms

NCT00553410 2020-03-11

SOLE

Phase 3 Completed

4,884 enrolled 14 charts

Breast

Breast Neoplasms

NCT02995772 2019-06-19

Neoadjuvant Hormonal Therapy Compared to Neoadjuvant Chemotherapy in Stage IIIB/C and IV Breast Cancer Patients

Phase 3 Completed

122 enrolled

Breast

Breast Neoplasms

NCT00171704 2017-03-03

A Study to Evaluate the Effect of Letrozole and Tamoxifen on Bone and Lipids in Postmenopausal Women With Breast Cancer

Phase 3 Completed

263 enrolled 12 charts

Breast

Breast Neoplasms

NCT00329940 2017-02-24

Safety and Rheumatologic Tolerability of Letrozole in Postmenopausal Patients With Hormone Receptor Positive Breast Cancer

Phase 3 Completed

200 enrolled

Breast

Breast Neoplasms

NCT00332852 2017-02-23

Letrozole as Early Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer

Phase 3 Completed

655 enrolled

Breast

Breast Neoplasms

NCT00107263 2016-12-06

Zoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast Cancer

Phase 3 Completed

558 enrolled

Breast

Breast Neoplasms, Osteoporosis

NCT00248170 2016-04-19

FACE

Phase 3 Completed

4,172 enrolled 7 charts

Breast

Breast Neoplasms

NCT00044291 2015-07-31

Phase III Study of Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer

Phase 3 Completed

865 enrolled

Breast

Breast Neoplasms, Neoplasms, Hormone-Dependent, Carcinoma, Ductal, Breast, Carcinoma, Lobular

NCT00963729 2013-08-12

Chemotherapy or Letrozole Before Surgery in Treating Postmenopausal Women With Breast Cancer That Can Be Removed By Surgery

Phase 3 Completed

756 enrolled

Breast

Breast Neoplasms

NCT01577017 2012-06-14

The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)

Phase 3 Completed

150 enrolled

Polycystic Ovary Syndrome

NCT00171340 2012-04-16

Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.

Phase 3 Completed

1,065 enrolled 10 charts

Breast

Bone Diseases, Metabolic, Breast Neoplasms

NCT00171314 2012-04-11

The Use of Zoledronic Acid to Prevent Cancer-treatment Bone Loss in Post-menopausal Women Receiving Adjuvant Letrozole for Breast Cancer

Phase 3 Completed

527 enrolled 11 charts

Breast

Breast Neoplasms

NCT00332709 2011-11-16

Safety/Efficacy of Letrozole Monotherapy or in Combination With Zoledronic Acid as Extended Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer

Phase 3 Completed

83 enrolled 14 charts

Breast

Breast Neoplasms, Osteoporosis

Clinical Trials

MNEMOSYNE

MECCA

Letrozole Step up Protocol for Ovulation Induction in Infertile Women With Polycystic Ovary Syndrome

PADA-1

A Study Of Palbociclib (PD-0332991) + Letrozole VS. Placebo+ Letrozole For 1st Line Treatment Of Asian Postmenopausal Women With ER+/HER2- Advanced Breast Cancer [PALOMA-4]

EMERALD

Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage IIIB or Stage IV Breast Cancer

Exemestane, Letrozole, or Anastrozole in Treating Postmenopausal Women Who Are Undergoing Surgery for Stage II or Stage III Breast Cancer

Letrozole or Tamoxifen Citrate in Treating Older Postmenopausal Women Undergoing Surgery for Breast Cancer

PALOMA-2

BioItaLEE

Comparison Between Two Ovulation Induction Therapies and LOD on Clinical Outcomes in CC-Resistant PCOS Women

Letrozole Dose Increments in PCOS Patients Resistant to Letrozole

MONALEESA-7

COMPLEEMENT-1

Palbociclib Plus Letrozole For Postmenopausal Women With HR(+) HER2(-) Advanced Breast Cancer For Whom Letrozole Is Deemed Appropriate

Study for Women and Men With Hormone-receptor Positive Locally Advanced or Metastatic Breast Cancer

PCOSAPct

Study Comparing Lapatinib (GW572016) And Letrozole Versus Letrozole In Subjects With Advanced Or Metastatic Breast Cancer

MAIN-A

Letrozole After Tamoxifen in Treating Women With Breast Cancer

SOLE

Neoadjuvant Hormonal Therapy Compared to Neoadjuvant Chemotherapy in Stage IIIB/C and IV Breast Cancer Patients

A Study to Evaluate the Effect of Letrozole and Tamoxifen on Bone and Lipids in Postmenopausal Women With Breast Cancer

Safety and Rheumatologic Tolerability of Letrozole in Postmenopausal Patients With Hormone Receptor Positive Breast Cancer

Letrozole as Early Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer

Zoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast Cancer

FACE

Phase III Study of Atamestane Plus Toremifene Versus Letrozole in Advanced Breast Cancer

Chemotherapy or Letrozole Before Surgery in Treating Postmenopausal Women With Breast Cancer That Can Be Removed By Surgery

The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)

Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.

The Use of Zoledronic Acid to Prevent Cancer-treatment Bone Loss in Post-menopausal Women Receiving Adjuvant Letrozole for Breast Cancer

Safety/Efficacy of Letrozole Monotherapy or in Combination With Zoledronic Acid as Extended Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer