Clinical Trials

Phase 3 Active not recruiting

186 enrolled

Other neoplasm

Venentoclax

NCT00602641 2026-03-03

Melphalan, Prednisone, and Thalidomide or Lenalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

306 enrolled 12 charts

Multiple Myeloma

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

750 enrolled

CNS

Neuroblastoma, Ganglioneuroblastoma

NCT01208766 2026-01-06

HO95

1,503 enrolled

Phase 3 Active not recruiting

Multiple Myeloma, Neoplasms, Plasma Cell

NCT05457556 2025-12-22

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

435 enrolled

LymphoidMyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02195479 2025-08-22

A Study of Combination of Daratumumab and Velcade (Bortezomib) Melphalan-Prednisone (DVMP) Compared to Velcade Melphalan-Prednisone (VMP) in Participants With Previously Untreated Multiple Myeloma

706 enrolled 29 charts

Phase 3 Active not recruiting

Multiple Myeloma

NCT00734877 2025-06-29

TT4B

382 enrolled

Multiple Myeloma

NCT05991908 2025-02-18

Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies

MyeloidOther hematologic neoplasm

222 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT06829472 2025-02-17

Conditioning Regimen of Melphalan-busulfan and Fludarabine: a Randomized Study of Different Dose of Melphalan

Other hematologic neoplasm

120 enrolled

Leukemia, Myeloid, Acute

NCT05674539 2025-02-10

Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Phase 3 Enrolling by invitation

200 enrolled

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01093196 2024-11-07

Lenalidomide and Dexamethasone Versus Melphalan Prednisone and Lenalidomide Versus Cyclophosphamide, Prednisone and Lenalidomide in Elderly Multiple Myeloma Patients

660 enrolled

Disease, Multiple Myeloma

NCT01091831 2024-11-06

Cyclophosphamide, Lenalidomide and Dexamethasone (CRD) Versus Melphalan (200 mg/m2) Followed By Autologous Stem Cell Transplant (ASCT) In Newly Diagnosed Multiple Myeloma Subjects

389 enrolled

Phase 3 Not yet recruiting

Multiple Myeloma

NCT06613035 2024-09-25

Twice-per-weekSelinexor, 2 Days Melphalan

126 enrolled

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT00551928 2024-07-22

MPRvsMEL200

402 enrolled

Multiple Myeloma

NCT03217812 2024-04-25

A Study of VELCADE (Bortezomib) Melphalan-Prednisone (VMP) Compared to Daratumumab in Combination With VMP (D-VMP), in Participants With Previously Untreated Multiple Myeloma Who Are Ineligible for High-Dose Therapy (Asia Pacific Region)

220 enrolled

Multiple Myeloma

NCT02678572 2023-12-21

FOCUS

102 enrolled 1 FDA

Dermatologic

Uveal Melanoma

NCT05022901 2023-12-21

An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular Melanoma

MyeloidOther hematologic neoplasm

30 enrolled

Dermatologic

Uveal Melanoma

NCT01339910 2023-01-04

BMT CTN 0901

Phase 3 Terminated

272 enrolled 29 charts

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT02063022 2022-09-19

EW-1

278 enrolled

Sarcoma

Sarcoma, Ewing

NCT05466318 2022-07-25

ChiCGB vs BEAM in High-risk or R/R Lymphomas

306 enrolled

Lymphoma, T-Cell, Lymphoma, Large B-Cell, Diffuse

NCT02197221 2022-05-23

IFM2014-02

300 enrolled

Multiple Myeloma

NCT00567567 2022-04-28

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

665 enrolled 26 charts

CNS

Neuroblastoma

NCT01078454 2022-02-01

Melphalan and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Systemic Light-Chain Amyloidosis

11 enrolled 6 charts

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT00324727 2021-06-21

Hepatic Arterial Infusion With Melphalan Compared With Standard Therapy in Treating Patients With Unresectable Liver Metastases Due to Melanoma

93 enrolled

Dermatologic

Uveal Melanoma, Melanoma, Neoplasm Metastasis

NCT04799002 2021-03-16

Topotecan and Melphalan for Retinoblastoma

50 enrolled

Other solid neoplasm

Retinoblastoma

NCT01704716 2020-10-23

High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN)

3,300 enrolled

CNS

Neuroblastoma

NCT01413178 2020-04-21

A Randomized Trial to Compare Busulfan + Melphalan 140 mg/m2 With Melphalan 200 mg/m2 as Preparative Regimen for Autologous Hematopoietic Stem Cell Transplantation for Multiple Myeloma

205 enrolled 11 charts

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00002678 2020-04-02

Combination Chemotherapy in Treating Patients With Multiple Myeloma

595 enrolled

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00689936 2019-11-20

FIRST

1,623 enrolled 56 charts

Multiple Myeloma

NCT00137995 2019-08-28

R-ICE Versus R-DHAP in Patients Aged 18-65 With Relapse Diffuse Large B-cell Lymphoma

481 enrolled

Lymphoma, Lymphoma, Large B-Cell, Diffuse

NCT01818752 2019-08-26

CLARION

955 enrolled 20 charts

Multiple Myeloma

NCT02489500 2018-09-10

VelRand

Phase 3 Terminated

3 enrolled 11 charts

Immunoglobulin Light-chain Amyloidosis

NCT01916252 2017-09-27

GEM2012MENOS65

460 enrolled

Multiple Myeloma

NCT01277016 2017-03-10

EMN-03

110 enrolled

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT00920153 2016-09-16

Three Different Therapy Regimens in Treating Patients With Previously Untreated Hodgkin Lymphoma

Phase 3 Terminated

442 enrolled

Hodgkin Disease, Lymphoma

NCT00477971 2016-05-17

Low-Dose Melphalan and Dexamethasone Compared With High-Dose Melphalan Followed By Autologous Stem Cell Transplant in Treating Patients With Primary Systemic Amyloidosis

89 enrolled 11 charts

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma, Neoplasms, Plasma Cell

NCT00892346 2016-05-10

Single Autologous Stem Cell Transplantation Followed by Maintenance Therapy as Front-line Treatment for Myeloma

Phase 3 Suspended

80 enrolled

Multiple Myeloma

NCT00083551 2015-11-23

UARK 98-026 TT II: Multiple Myeloma Evaluating Anti-Angiogenesis With Thalidomide and Post-Transplant Consolidation Chemotherapy

668 enrolled 7 charts

Multiple Myeloma, Neoplasms

NCT00217438 2015-08-21

Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple Myeloma

130 enrolled 6 charts

Multiple Myeloma

NCT00002548 2015-03-06

SWOG-9321 Melphalan, TBI, and Transplant vs Combo Chemo in Untreated Myeloma

899 enrolled

Multiple Myeloma

NCT02288741 2014-11-11

DSMM-II

549 enrolled

Multiple Myeloma

NCT00020566 2014-06-24

Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma

1,200 enrolled

Sarcoma

Sarcoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00507416 2014-05-01

UPFRONT

502 enrolled 17 charts

Multiple Myeloma

NCT00002599 2013-12-19

Combination Chemotherapy and Interferon Alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma

750 enrolled

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00002653 2013-12-19

Combination Chemotherapy With or Without Cyclophosphamide and Prednisone in Treating Older Patients With Multiple Myeloma

1,000 enrolled

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00014339 2013-12-18

Chemotherapy With or Without Wobe-Mugos E in Treating Patients With Stage II or Stage III Multiple Myeloma

Multiple Myeloma, Neoplasms, Plasma Cell

NCT01998503 2013-11-29

Bortezomib and Dexamethasone Followed by ASCT Compared With ASCT Alone in Treating Patients With AL Amyloidosis

56 enrolled

Immunoglobulin Light-chain Amyloidosis, Amyloidosis

NCT00205764 2013-11-25

Tandem High Dose Melphalan Versus Triple Intermediate Dose Melphalan and Stem Cell Transplantation in Induction Phase and Prednisolone/IFN Versus IFN in Maintenance Therapy

212 enrolled

Multiple Myeloma

NCT00003578 2013-09-20

High Dose Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Intermediate- or High-Grade Non-Hodgkin's Lymphoma

500 enrolled

Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse

NCT00003603 2013-09-20

Chemotherapy Plus Steroid Therapy in Treating Patients With Multiple Myeloma

660 enrolled