Clinical Trials Browser

Lymphadenopathy, Anemia, Fatigue, Fever, Lymphocytosis, Multiple Myeloma, Splenomegaly, Thrombocytopenia, Weight Loss, Leukemia, Lymphocytic, Chronic, B-Cell

NCT02244567 2021-02-02

U-C OC IN PCOS

Phase 1 Unknown

100 enrolled

Polycystic Ovary Syndrome

NCT01981525 2020-12-14

A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome

Phase 1 Completed

26 enrolled

Li-Fraumeni Syndrome

NCT04621669 2020-11-09

Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride

Phase 1 Unknown

18 enrolled

Drug-drug Interaction,SHR3680

NCT02325401 2020-06-11

Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma

Phase 1 Completed

20 enrolled 11 charts

Head & Neck

Head and Neck Neoplasms

NCT02050009 2019-02-20

Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 1 Withdrawn

Gynecologic

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms

NCT01849276 2019-01-31

Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML

Phase 1 Terminated

2 enrolled 9 charts

Other hematologic neoplasm

Congenital Abnormalities, Blast Crisis, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT03465345 2018-08-03

Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients

Phase 1 Withdrawn

Genitourinary

Prostatic Neoplasms

NCT02149459 2017-10-27

SMC 0712-13

Phase 1 Unknown

18 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Insulin Resistance, Ketosis

NCT01650506 2017-08-30

Study of Erlotinib and Metformin in Triple Negative Breast Cancer

Phase 1 Completed

8 enrolled

Breast

Breast Neoplasms

NCT01324180 2017-08-07

Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)

Phase 1 Completed

14 enrolled

LymphoidOther hematologic neoplasm

Recurrence, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01442870 2017-05-09

Evaluation of Clinical Safety of Combining Metformin With Anticancer Chemotherapy

Phase 1 Completed

105 enrolled

Tumor-Agnostic

Neoplasms

NCT00933309 2016-02-19

The Impact of Obesity and Obesity Treatments on Breast Cancer

Phase 1 Completed

25 enrolled

BreastOther

Breast Neoplasms, Obesity

NCT01816659 2015-11-18

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Phase 1 Terminated

3 enrolled

Gastrointestinal

Colorectal Neoplasms

NCT01087983 2015-11-11

Lapatinib With Sirolimus or Metformin

Phase 1 Completed

111 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT01954732 2015-07-15

Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery

Phase 1 Withdrawn

Gastrointestinal

Pancreatic Neoplasms

NCT01440127 2015-03-26

Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers

Phase 1 Terminated

9 enrolled

Gastrointestinal

Colonic Neoplasms

NCT00659568 2013-05-30

Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma

Phase 1 Completed

28 enrolled

BreastDermatologicGenitourinaryGynecologicLymphoidOther hematologic neoplasmThoracic

Breast Neoplasms, Burkitt Lymphoma, Carcinoma, Renal Cell, Hodgkin Disease, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Mycosis Fungoides, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Endometrial Neoplasms, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Small Cell Lung Carcinoma