NCT02437656 2026-03-16
METCAP
Centre Oscar Lambret
Phase 2 Completed
Clinical Trials
305 trialsNCT07226453 2026-03-13
PNOC041
University of California, San Francisco
Phase 2 Recruiting
NCT07459595 2026-03-10
Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study
Combined Military Hospital Gujranwala
Phase 1 Not yet recruiting
NCT05965908 2026-03-06
Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome
Beni-Suef University
Phase 3 Completed
NCT02946996 2026-03-05
Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
Medical University of South Carolina
Phase 2 Terminated
NCT07291297 2026-03-05
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Wake Forest University Health Sciences
Phase 2 Recruiting
NCT03905941 2026-02-23
SHK002
University of Virginia
Phase EARLY_PHASE1 Withdrawn
NCT04850846 2026-02-09
Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma
Dana-Farber Cancer Institute
Phase 2 Active not recruiting
NCT05767515 2026-02-09
PCOS
Khyber Medical University Peshawar
Phase NA Completed
NCT07387900 2026-02-06
Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia
Cairo University
Phase 2 Recruiting
NCT02336087 2026-02-04
Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery
City of Hope Medical Center
Phase 1 Active not recruiting
NCT07387679 2026-02-04
Myo-inositol Versus Metformin in Patients With Polycystic Ovarian Syndrome to Treat Obesity
RESnTEC, Institute of Research
Phase NA Completed
NCT07380841 2026-02-02
PCOS-COMBO (9)
Islamabad Medical and Dental College
Phase NA Completed
NCT06763328 2026-01-22
Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy
City of Hope Medical Center
Phase 3 Recruiting
NCT06044025 2026-01-15
A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
University of Arkansas
Phase 1 Recruiting
NCT05023967 2026-01-05
Metformin and Nightly Fasting in Women With Early Breast Cancer
M.D. Anderson Cancer Center
Phase 2 Active not recruiting
NCT04414540 2025-12-19
Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients
University of Cincinnati
Phase 2 Active not recruiting
NCT04691960 2025-12-19
A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging
Weill Medical College of Cornell University
Phase 2 Active not recruiting
NCT05183204 2025-12-18
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Weill Medical College of Cornell University
Phase 2 Suspended
NCT03109847 2025-12-11
Metformin to Mitigate Sequelae of Radioactive Iodine Treatment for Thyroid Cancers
Thomas Jefferson University
Phase 2 Terminated
NCT05515978 2025-12-04
PragMet
University of Colorado, Denver
Phase EARLY_PHASE1 Recruiting
NCT05802212 2025-11-25
Effect of Metformin on Patients With Polycystic Ovary Syndrome
Peking University Third Hospital
Phase NA Completed
NCT01797523 2025-11-06
A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma
M.D. Anderson Cancer Center
Phase 2 Active not recruiting
NCT07098299 2025-11-06
Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies
Barbara Ann Karmanos Cancer Institute
Phase 1 Recruiting
NCT04742751 2025-10-31
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
St. Jude Children's Research Hospital
Phase 2 Active not recruiting
NCT03889795 2025-10-20
Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
University of Toledo
Phase 1 Active not recruiting
NCT02186847 2025-10-09
Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer
NRG Oncology
Phase 2 Completed
NCT04931017 2025-10-07
Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer
Northwestern University
Phase 2 Active not recruiting
NCT06479434 2025-10-07
Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls
Aga Khan University
Phase NA Completed
NCT05036226 2025-10-06
COAST
Medical University of South Carolina
Phase 1/2 Recruiting
NCT02755844 2025-10-02
ENDOLA
Hospices Civils de Lyon
Phase 1/2 Completed
NCT05237960 2025-09-29
Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia
University of Arizona
Phase 2 Active not recruiting
NCT05680805 2025-09-19
Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Phase 4 Active not recruiting
NCT01750567 2025-09-09
A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL
University of Michigan Rogel Cancer Center
Phase 2 Completed
NCT06728982 2025-08-01
Impact Of Metformin In Rectal Cancer Patients
Minia University
Phase 2/3 Completed
NCT04300790 2025-07-29
METALLICA
MedSIR
Phase 2 Completed
NCT05929495 2025-07-25
Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma
University of Milano Bicocca
Phase 2 Recruiting
NCT02040376 2025-07-16
Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma
The Hospital for Sick Children
Phase 3 Completed
NCT06687876 2025-07-10
MEMENTO
Amsterdam UMC, location VUmc
Phase 2 Recruiting
NCT02500147 2025-07-02
Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)
Columbia University
Phase 4 Terminated
NCT02780024 2025-06-26
Metformin, Neo-adjuvant Temozolomide and Hypo- Accelerated Radiotherapy Followed by Adjuvant TMZ in Patients With GBM
McGill University Health Centre/Research Institute of the McGill University Health Centre
Phase 2 Active not recruiting
NCT03675893 2025-06-15
RESOLVE: Abemaciclib + Letrozole +/- Metformin, Zotatifin, or Gedatolisib in Endometrial or Low-Grade Serous Ovarian Cancer
Dana-Farber Cancer Institute
Phase 2 Recruiting
NCT05966792 2025-06-11
SGLT2 Inhibitors in Treating Patients With PCOS
Shanghai 10th People's Hospital
Phase NA Enrolling by invitation
NCT02122185 2025-06-08
Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
University of Chicago
Phase 2 Active not recruiting
NCT06742710 2025-05-29
LITOP
Peking University Third Hospital
Phase 4 Recruiting
NCT02083692 2025-05-15
Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic Uncoupling
Thomas Jefferson University
Phase EARLY_PHASE1 Completed
NCT03618654 2025-05-15
Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma
Thomas Jefferson University
Phase EARLY_PHASE1 Completed
NCT05536037 2025-05-15
Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions
Thomas Jefferson University
Phase 1 Terminated
NCT06140108 2025-05-14
Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity
SINA Health Education and Welfare Trust
Phase 2/3 Completed
NCT01430351 2025-05-07
Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy
M.D. Anderson Cancer Center
Phase 1 Terminated