Clinical Trials

Polycystic Ovary Syndrome

NCT01864096 2024-01-24

MAST

Phase EARLY_PHASE1 Unknown

408 enrolled

Genitourinary

Neoplasms, Prostatic Neoplasms

NCT01422746 2023-10-27

Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

20 enrolled

Obesity, Polycystic Ovary Syndrome

NCT05952882 2023-10-23

Liraglutide and Metformin Combination on Weight Loss, Metabolic - Endocrine Parameters and Pregnancy Rate in Women With PCOS, Obesity and Infertility

188 enrolled

Infertility, Female, Insulin Resistance, Obesity, Polycystic Ovary Syndrome, Weight Loss

NCT04033107 2023-09-28

High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors

30 enrolled

Liver Neoplasms, Pancreatic Neoplasms, Stomach Neoplasms, Colorectal Neoplasms

NCT05445791 2023-06-27

METLUNG

312 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04792749 2023-04-13

Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer

77 enrolled

Gynecologic

Endometrial Neoplasms

NCT04508634 2023-04-12

Treating Obese PCOS Patients With LSG vs. Met

90 enrolled

Polycystic Ovary Syndrome

NCT04248998 2023-01-18

BREAKFAST

30 enrolled

Phase EARLY_PHASE1 Unknown

Triple Negative Breast Neoplasms

NCT05680662 2023-01-11

The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism

200 enrolled

Triple Negative Breast Neoplasms

NCT02874430 2022-12-15

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

27 enrolled

Breast Neoplasms

NCT05507398 2022-10-31

The Anti-tumor Effect of Metformin And Atorvastatin in Breast Cancer

Breast Cancer Female

NCT04984070 2022-10-05

PCOS

Anxiety Disorders, Bipolar Disorder, Depression, Polycystic Ovary Syndrome

NCT05519813 2022-08-29

Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.

60 enrolled

Polycystic Ovary Syndrome

NCT05463627 2022-07-19

Effects of Metformin on Metabolic and Reproductive Outcomes in Chinese PCOS Patients

Unknown

1,440 enrolled

Polycystic Ovary Syndrome

NCT05292573 2022-03-23

Longitudinal Follow-up in Women With Endometrial Hyperplasia Without Atypia

1,000 enrolled

Female

NCT05200793 2022-01-21

Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome

75 enrolled

Polycystic Ovary Syndrome

NCT00038727 2021-12-28

DPPOS

2,779 enrolled 16 charts

Diabetes Mellitus, Diabetes Mellitus, Type 2, Neoplasms, Obesity, Prediabetic State

NCT03238495 2021-12-07

HERMET

HER2-positive Breast Cancer

NCT02294006 2021-09-09

MetNET1

26 enrolled

Adenoma, Islet Cell

NCT04780854 2021-07-28

Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)

68 enrolled

Tumor-Agnostic

Neoplasms

NCT04926155 2021-06-14

The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer

234 enrolled

Genitourinary

Prostatic Neoplasms

NCT04268563 2021-03-22

Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients

Phase 1/2 Unknown

Infertility, Polycystic Ovary Syndrome

NCT02244567 2021-02-02

U-C OC IN PCOS

Phase 1 Unknown

Polycystic Ovary Syndrome

NCT04621669 2020-11-09

Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride

Phase 1 Unknown

18 enrolled

Drug-drug Interaction,SHR3680

NCT03048500 2020-10-14

Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

17 enrolled 10 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04559308 2020-09-22

The Effect of Metformin on Breast Cancer Patients

Breast Neoplasms

NCT04298684 2020-09-11

METNODTHYR

90 enrolled

Head & Neck

Diabetes Mellitus, Type 2, Insulin Resistance, Thyroid Nodule

NCT04387630 2020-06-11

Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.

Phase 2/3 Unknown

120 enrolled

Breast Neoplasms

NCT03600363 2020-03-11

A Clinical Trial of Metformin in the Maintenance of Non-Hodgkin's Lymphoma Patients

250 enrolled

Lymphoid

Lymphoma, Follicular, Lymphoma, Large B-Cell, Diffuse

NCT04001725 2019-11-13

OPTIMAL

BreastCNSDermatologicThoracic

110 enrolled

Brain Neoplasms, Breast Neoplasms, Diabetes Mellitus, Lung Neoplasms, Melanoma, Neoplasms

NCT04151459 2019-11-05

Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients

18 enrolled

Obesity, Morbid, Polycystic Ovary Syndrome

NCT02614339 2019-09-18

Effect of Adjunctive Metformin on Recurrence of Non-DM Colorectal Cancer Stage II High-risk/ III Colorectal Cancer

593 enrolled

Non-DM Stage II High-risk Colorectal Cancer

NCT02506777 2019-09-04

MBC1

96 enrolled

Breast Neoplasms

NCT02506790 2019-09-04

Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer

96 enrolled

Breast Neoplasms

NCT04029272 2019-07-23

Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients

Polycystic Ovary Syndrome

NCT03874000 2019-03-19

SMART

43 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neoplasms

NCT03833466 2019-02-15

ECMTPneo

15 enrolled

Esophageal Squamous Cell Carcinoma

NCT03684707 2018-09-26

Cancer Chemoprevention by Metformin Hydrochloride Compared to Placebo in Oral Potentially Malignant Lesions

30 enrolled

Head & Neck

Mouth Neoplasms

NCT03685409 2018-09-26

Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions

62 enrolled

Head & Neck

Mouth Neoplasms

NCT01389778 2018-08-16

Polycystic Ovary Syndrome Genetics and Treatment Response

200 enrolled

Polycystic Ovary Syndrome

NCT02198417 2018-08-16

Metformin Treatment in Polycystic Ovary Syndrome (PCOS)

20 enrolled

Acne Vulgaris, Infertility, Menstruation Disturbances, Polycystic Ovary Syndrome

NCT03486626 2018-06-26

Endometrial Thickness and Subendometrial Vascularity in Anovulatory Polycystic Ovarian Syndrome Patients Treated by Metformin

85 enrolled

Anovulation, Polycystic Ovary Syndrome

NCT03538704 2018-05-29

ECFerSp

Gynecologic

Recurrence, Endometrial Neoplasms

NCT02978547 2018-01-18

Metformin 001

20 enrolled

Resectable Pancreatic Ductal Adenocarcinoma

NCT02149459 2017-10-27

SMC 0712-13

Phase 1 Unknown

18 enrolled

CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Insulin Resistance, Ketosis

NCT01930864 2017-06-22

Metformin Plus Irinotecan for Refractory Colorectal Cancer

41 enrolled

Adenocarcinoma, Colorectal Neoplasms

NCT03137186 2017-05-02

Mansmed

120 enrolled

Genitourinary

Prostatic Neoplasms

NCT02990728 2016-12-13

Mirena® ± Metformin as Fertility-preserving Treatment for Young Asian Women With Early Endometrial Cancer